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2.4.2.21: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

This is an abbreviated version!
For detailed information about nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, go to the full flat file.

Word Map on EC 2.4.2.21

Reaction

beta-nicotinate D-ribonucleotide
+
5,6-Dimethylbenzimidazole
=
nicotinate
 +
alpha-ribazole 5'-phosphate
 +
H+

Synonyms

5,6-dimethylbenzimidazole phosphoribosyltransferase, ArsAB, CblT, CobT, CobT2, N(1)-alpha-phosphoribosyltransferase, N1-alpha-phosphoribosyltransferase, NaMN:DMB phosphoribosyltransferase, nicotinate mononucleotide-dimethylbenzimidazole phosphoribosyltransferase, nicotinate mononucleotide:5,6-dimethylbenzimidazolyl phosphoribosyltransferase, nicotinate ribonucleotide:benzimidazole (adenine) phosphoribosyltransferase, NN:DBI PRT, phosphoribosyltransferase, nicotinate mononucleotide-dimethylbenzimidazole, SoArsAB

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.21 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

Specific Activity

Specific Activity on EC 2.4.2.21 - nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0000007
substrate p-cresol, pH 9.0, 37°C, mutant M87Q/I321S
0.0000024
substrate 5,6-dimethylbenzimidazole, pH 9.0, 37°C, mutant M87Q/I321S
0.0000083
substrate p-cresol, pH 9.0, 37°C, mutant I321S
0.0000142
substrate p-cresol, pH 9.0, 37°C, mutant M87Q
0.0000167
substrate 5,6-dimethylbenzimidazole, pH 9.0, 37°C, mutant I321S
0.0000376
substrate p-cresol, pH 9.0, 37°C, wild-type
0.00016
substrate 5,6-dimethylbenzimidazole, pH 9.0, 37°C, wild-type
0.000192
substrate 5,6-dimethylbenzimidazole, pH 9.0, 37°C, mutant M87Q
0.0025
-
cell extract, substrate NAD+
0.035
-
cell extract, substrate beta-nicotinate D-riboadenosine
0.1
mutant G257D, at 37°C
0.2
mutant G320D, at 37°C
0.5
mutant G171D, at 37°C
11
mutant G257A, at 37°C
25
mutant C160A, at 37°C
30
wild-type, at 37°C
additional information