2.4.2.2: pyrimidine-nucleoside phosphorylase

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For detailed information about pyrimidine-nucleoside phosphorylase, go to the full flat file.

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Synonyms

AmPyNP, BbPyNP, BfPyNP, BsPyNP, deoA, EC 2.4.2.23, GsPyNP, GtPyNP, LpPyNP, nucleoside phosphorylase, PDP, phosphorylase, pyrimidine nucleoside, Py-NPase, PYNP, pynpase, pyrimidine nucleoside phosphorylase, pyrimidine ribonucleoside phosphorylase, pyrimidine-nucleoside phosphorylase, pyrimidine/purine nucleoside phosphorylase, TTHA1771, TtPyNP, udp, UPase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.2 pyrimidine-nucleoside phosphorylase

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Results	in table
1	Activating Compound
13423	AA Sequence
8	Application
1	CAS Registry Number
18	Cloned(Commentary)
6	Crystallization (Commentary)
85	Disease/ Diagnostics
1	Expression
9	General Information
3	General Stability
10	IC50 Value
7	Inhibitors
12	kcat/KM [mM/s]
2	Ki Value [mM]
50	KM Value [mM]
7	Molecular Weight [Da]
71	Natural Substrates/ Products (Substrates)
136	Organism
1	Oxidation Stability
5	Pathway
10	PDB ID
19	pH Optimum
3	pH Range
2	pH Stability
6	Protein Variants
11	Purification (Commentary)
4	Reaction
5	Reaction Type
45	Reference
1	Renatured (Commentary)
2	Source Tissue
15	Specific Activity [micromol/min/mg]
2	Storage Stability
194	Substrates and Products (Substrate)
11	Subunits
62	Synonyms
1	Systematic Name
15	Temperature Optimum [°C]
5	Temperature Range [°C]
19	Temperature Stability [°C]
20	Turnover Number [1/s]

Source Tissue

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Source Tissue on EC 2.4.2.2 - pyrimidine-nucleoside phosphorylase

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SOURCE TISSUE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

SOURCE

colorectal cancer cell

Homo sapiens

-

PyNPase level quantified by sandwich ELISA using monoclonal anti-human thimidine phosphorylase antibodies 104B and 232-2, no association between PyNPase level and recurrence, disease-free survival at year 2.2 better with low PyNPase levels and high PyNPase-to-dihydropyrimidine dihydrogenase ratio

692551

brenda

colorectum

Homo sapiens

-

PyNPase level quantified by sandwich ELISA using monoclonal anti-human thimidine phosphorylase antibodies 104B and 232-2

692551

brenda