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2.4.2.19: nicotinate-nucleotide diphosphorylase (carboxylating)

This is an abbreviated version!
For detailed information about nicotinate-nucleotide diphosphorylase (carboxylating), go to the full flat file.

Word Map on EC 2.4.2.19

Reaction

beta-nicotinate D-ribonucleotide
+
diphosphate
+
CO2
=
pyridine-2,3-dicarboxylate
+
5-phospho-alpha-D-ribose 1-diphosphate

Synonyms

BNA6, general stress protein 70 , GSP70 , Hp-QAPRTase, hQPRTase, M6_Spy1061, NAD pyrophosphorylase, NadC, nicotinate mononucleotide pyrophosphorylase (carboxylating) (EC 2.4.2.19), nicotinate-nucleotide pyrophosphorylase (carboxylating), nicotinate-nucleotide:pyrophosphate phospho-alpha-D-ribosyltransferase (decarboxylating), pyrophosphorylase, nicotinate mononucleotide (carboxylating), QAPRTase, QPRT, QPRTase, QPRTase , QPT, QPT1, QPT2, quinolate phosphoribosyltransferase, quinolinate phosphoribosyl transferase, quinolinate phosphoribosyltansferase, quinolinate phosphoribosyltransferase, quinolinate phosphoribosyltransferase (decarboxylating), quinolinate phosphoribosyltransferase 1, quinolinate phosphoribosyltransferase 2, quinolinate phosphoribosyltransferase [decarboxylating] , quinolinic acid phosphoribosyl transferase, quinolinic acid phosphoribosyltransferase, quinolinic phosphoribosyltransferase, sp.NadC, spNadC, TM1645, type II quinolic acid phosphoribosyltransferase, type II quinolinic acid phosphoribosyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.19 nicotinate-nucleotide diphosphorylase (carboxylating)

Substrates Products

Substrates Products on EC 2.4.2.19 - nicotinate-nucleotide diphosphorylase (carboxylating)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
beta-nicotinate D-ribonucleotide + diphosphate + CO2
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
show the reaction diagram
M1KCW7
-
-
-
?
nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O
beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate
show the reaction diagram
phosphoribosyl diphosphate + quinolinic acid
nicotinate mononucleotide + diphosphate + CO2
show the reaction diagram
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
beta-nicotinate D-ribonucleotide + diphosphate + CO2
show the reaction diagram
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
show the reaction diagram
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate + H+
beta-nicotinate D-ribonucleotide + diphosphate + CO2
show the reaction diagram
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
show the reaction diagram
additional information
?
-