2.4.2.19: nicotinate-nucleotide diphosphorylase (carboxylating)
This is an abbreviated version!
For detailed information about nicotinate-nucleotide diphosphorylase (carboxylating), go to the full flat file.
Word Map on EC 2.4.2.19
Reaction
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Synonyms
BNA6, general stress protein 70 , GSP70 , Hp-QAPRTase, hQPRTase, M6_Spy1061, NAD pyrophosphorylase, NadC, nicotinate mononucleotide pyrophosphorylase (carboxylating) (EC 2.4.2.19), nicotinate-nucleotide pyrophosphorylase (carboxylating), nicotinate-nucleotide:pyrophosphate phospho-alpha-D-ribosyltransferase (decarboxylating), pyrophosphorylase, nicotinate mononucleotide (carboxylating), QAPRTase, QPRT, QPRTase, QPRTase , QPT, QPT1, QPT2, quinolate phosphoribosyltransferase, quinolinate phosphoribosyl transferase, quinolinate phosphoribosyltansferase, quinolinate phosphoribosyltransferase, quinolinate phosphoribosyltransferase (decarboxylating), quinolinate phosphoribosyltransferase 1, quinolinate phosphoribosyltransferase 2, quinolinate phosphoribosyltransferase [decarboxylating] , quinolinic acid phosphoribosyl transferase, quinolinic acid phosphoribosyltransferase, quinolinic phosphoribosyltransferase, sp.NadC, spNadC, TM1645, type II quinolic acid phosphoribosyltransferase, type II quinolinic acid phosphoribosyltransferase
ECTree
KCat KM Value
KCat KM Value on EC 2.4.2.19 - nicotinate-nucleotide diphosphorylase (carboxylating)
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0.00004 - 18
5-phospho-alpha-D-ribose 1-diphosphate
0.32
nicotinic acid
-
mutant K185A, at 25°C
0.0011 - 52
quinolinic acid
0.00004
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant E214A
0.000049
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant E214D
0.000064
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant R118A, at 25°C
0.0007
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant K284A
0.00073
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant K185A, at 25°C
0.035
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant R152A, at 25°C
1.8
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant H188A, at 25°C
3.9
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant E214Q
12
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant D235A
18
5-phospho-alpha-D-ribose 1-diphosphate
-
wild-type
18
5-phospho-alpha-D-ribose 1-diphosphate
-
wild-type, at 25°C
0.0011
quinolinic acid
-
mutant K185A, at 25°C
0.0015
quinolinic acid
-
mutant R118A, at 25°C
0.0019
quinolinic acid
-
mutant E214A
0.0019
quinolinic acid
-
mutant E214D
0.023
quinolinic acid
-
mutant K284A
0.1
quinolinic acid
-
mutant R152A, at 25°C
12
quinolinic acid
-
mutant E214Q
16
quinolinic acid
-
mutant H188A, at 25°C
37
quinolinic acid
-
wild-type
37
quinolinic acid
-
wild-type, at 25°C
52
quinolinic acid
-
mutant D235A