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2.4.2.18: anthranilate phosphoribosyltransferase

This is an abbreviated version!
For detailed information about anthranilate phosphoribosyltransferase, go to the full flat file.

Word Map on EC 2.4.2.18

Reaction

N-(5-phospho-D-ribosyl)-anthranilate
+
diphosphate
=
anthranilate
 +
5-phospho-alpha-D-ribose 1-diphosphate

Synonyms

AnPRT, anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase, anthranilate phosphoribosyl transferase, anthranilate phosphoribosylpyrophosphate phosphoribosyltransferase, anthranilate phosphoribosyltransferase, anthranilate PRT, anthranilate-5-phosphoribosylphosphate phosphoribosyltransferase, anthranilate-PP-ribose-P phosphoribosyltransferase, More, Pat, phosphoribosyl-anthranilate pyrophosphorylase, phosphoribosylanthranilate pyrophosphorylase, phosphoribosylanthranilate transferase, phosphoribosyltransferase, anthranilate, PR transferase, PRT, sAnPRT, ssAnPRT, SSO0890, ssTrpD, strpD, Trp D, TrpD, TTC1491

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.18 anthranilate phosphoribosyltransferase

Molecular Weight

Molecular Weight on EC 2.4.2.18 - anthranilate phosphoribosyltransferase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
150000
-
and 70000, disc gel electrophoresis
170000
-
sucrose density gradient sedimentation, complex with anthranilate synthase activity
220000
-
and larger than 1000000, strain trpAB1653trpR782, gel filtration
320000
-
strain TAX6trpR782, gel filtration
32400
double mutant M47D/I36E, analytical-gel filtration chromatography
34100
double mutant M47D/I36E, analytical ultracentrifugation (sedimentation equilibrium)
37000
-
2 * 37000, SDS-PAGE
38800
calculated for monomeric wild-type and mutants
40000
-
2 * 40000, SDS-PAGE
42000
-
2 * 42000, SDS-PAGE
43000
-
1 * 43000, SDS-PAGE
45000
60100
mutant M47D, analytical ultracentrifugation (sedimentation equilibrium)
61700
mutant M47D, analytical gel filtration chromatography
63400
mutant I36E, analytical gel filtration chromatography
64500
wild-type, analytical gel filtration chromatography
66000
mutant I36E, analytical ultracentrifugation (sedimentation equilibrium)
67000
70000
72000
-
x * 72000, strain trpAB1653trpR782, SDS-PAGE
72200
wild-type, analytical ultracentrifugation (sedimentation equilibrium)
75000
-
calculated from amino acid sequence
77700
calculated for the dimeric wild-type and mutants
78200
-
calculated from amino acid sequence
78700
-
calculated from amino acid sequence
79200
calculated from amino acid sequence
83000
-
sedimentation equilibrium
83700
-
calculated from amino acid sequence
90000
-
tryptophan auxotroph with no anthranilate synthase activity, sucrose density gradient sedimentation