2.4.2.16: urate-ribonucleoside phosphorylase

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For detailed information about urate-ribonucleoside phosphorylase, go to the full flat file.

Reaction

Synonyms

phosphorylase, urate ribonucleotide, UAR phosphorylase, urate ribonucleotide phosphorylase, urate-ribonucleotide:orthophosphate D-ribosyltransferase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.16 urate-ribonucleoside phosphorylase

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Results	in table
1	CAS Registry Number
13	Inhibitors
2	Ki Value [mM]
4	Natural Substrates/ Products (Substrates)
4	Organism
2	Pathway
1	pH Optimum
1	pH Range
1	pH Stability
1	Purification (Commentary)
1	Reaction
1	Reaction Type
4	Reference
16	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
8	Substrates and Products (Substrate)
4	Synonyms
1	Systematic Name
4	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 2.4.2.16 - urate-ribonucleoside phosphorylase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

1-Ribosyluracil

Canis lupus familiaris

-

1 mM, about 85% inhibition

639636

2-thio-6-oxopurine

Canis lupus familiaris

-

1 mM, 73% inhibition

639636

2-Thiouracil

Canis lupus familiaris

-

1 mM, 96% inhibition

639636

4-amino-5-imidazolecarboxamide

Canis lupus familiaris

-

1 mM, about 15% inhibition

639636

5-methyluracil

Canis lupus familiaris

-

1 mM, about 90% inhibition

639636

5-methyluridine

Canis lupus familiaris

-

1 mM, about 95% inhibition

639636

Colchicine

Canis lupus familiaris

-

1 mM, 43% inhibition, competitive

639636

guanosine

Canis lupus familiaris

-

1 mM, about 20% inhibition

639636

Inosine

Canis lupus familiaris

-

1 mM, about 25% inhibition

639636

p-chloromercuribenzoate

Canis lupus familiaris

-

reversed by cysteine

639636

Phenylbutazone

Canis lupus familiaris

-

1 mM, 30% inhibition, competitive

639636

Uracil

Canis lupus familiaris

-

1 mM, about 85% inhibition

639636

xanthine

Canis lupus familiaris

-

1 mM, 35% inhibition

639636