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2.4.2.12: nicotinamide phosphoribosyltransferase

This is an abbreviated version!
For detailed information about nicotinamide phosphoribosyltransferase, go to the full flat file.

Word Map on EC 2.4.2.12

Reaction

nicotinamide D-ribonucleotide
+
diphosphate
=
nicotinamide
+
5-phospho-alpha-D-ribose 1-diphosphate

Synonyms

eNAMPT, extracellular nicotinamide phosphoribosyltrasferase, iNAMPT, Nam phosphoribosyltransferase, NAmPRTase, Nampt, Nampt/PBEF/Visfatin, Nampt/visfatin, NAMPTA, NAMPTB, NAPRT, nicotinamide mononucleotide pyrophosphorylase, nicotinamide mononucleotide synthetase, nicotinamide phosphoribosyl transferase, nicotinamide phosphoribosyltransferase, nicotinamide phosphoribosyltransferase/Visfatin, NMN pyrophosphorylase, NMN synthetase, NMPRTase, PBEF, phosphoribosyltransferase, nicotinamide, pre-B cell colony enhancing factor, pre-B cell colony enhancing factor(PBEF), pre-B cell colony-enhancing factor, pre-B cell colony-enhancing factor (PBEF), pre-B cell colony-enhancing factor 1, pre-B colony enhancing factor, pre-B-cell colony enhancing factor, pre-B-cell colony-enhancing factor, Visfatin

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.12 nicotinamide phosphoribosyltransferase

pH Optimum

pH Optimum on EC 2.4.2.12 - nicotinamide phosphoribosyltransferase

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.8 - 7.6
-
-
7.4
assay at
7.5
for both, NMN synthesis and ATP hydrolysis activity
8.5 - 9
-
assay at pH 8.8. where NAD glycohydrolase is not active
8.8
-
assay at