2.4.2.10: orotate phosphoribosyltransferase

This is an abbreviated version!
For detailed information about orotate phosphoribosyltransferase, go to the full flat file.

Word Map on EC 2.4.2.10

2.4.2.10

pyrimidine

5-fluorouracil

thymidylate

dihydropyrimidine

uridine

thymidine

uracil

colorectal

dihydroorotase

pyre

fluoropyrimidine

4.1.1.23

orotidine-5'-monophosphate

5-fluoroorotic

transcarbamoylase

5-fu-based

leucovorin

phosphoribosylpyrophosphate

5-fluorouracil-based

5-fu-related

prototrophy

tegafur

odcase

dihydrouracil

succinate-grown

5-phosphoribosyl

fdump

5-fu-resistant

podospora

phosphoribosyltransferases

5-fluoro-2'-deoxyuridine

fluoropyrimidine-based

ompdc

5-phosphoribosyl-1-pyrophosphate

anserina

1-pyrophosphate

5-fluorouridine

pyrophosphorolysis

medicine

diagnostics

Reaction

Synonyms

More, OMP synthase, OPRT, OPRTase, orotate phosphoribosyl pyrophosphate transferase, orotate phosphoribosyl transferase, orotate phosphoribosyltransferase, orotate PRTase, orotic acid phosphoribosyltransferase, orotidine 5'-monophosphate pyrophosphorylase, orotidine 5'-phosphate pyrophosphorylase, orotidine monophosphate pyrophosphorylase, orotidine phosphoribosyltransferase, orotidine-5'-phosphate pyrophosphorylase, orotidylate phosphoribosyltransferase, orotidylate pyrophosphorylase, orotidylic acid phosphorylase, orotidylic acid pyrophosphorylase, orotidylic phosphorylase, orotidylic pyrophosphorylase, phosphoribosyltransferase, orotate, Pyr5, PyrE, rv0382c, type I phosphoribosyltransferase, ura5

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.2 Pentosyltransferases

2.4.2.10 orotate phosphoribosyltransferase

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Results	in table
1	Activating Compound
44599	AA Sequence
10	Application
1	CAS Registry Number
28	Cloned(Commentary)
9	Crystallization (Commentary)
1113	Disease/ Diagnostics
6	Expression
4	General Information
9	General Stability
136	Inhibitors
18	kcat/KM [mM/s]
93	Ki Value [mM]
93	KM Value [mM]
12	Localization
40	Metals/Ions
35	Molecular Weight [Da]
36	Natural Substrates/ Products (Substrates)
94	Organism
8	Pathway
108	PDB ID
15	pH Optimum
4	pH Range
2	pH Stability
2	pI Value
12	Protein Variants
31	Purification (Commentary)
8	Reaction
1	Reaction Type
91	Reference
52	Source Tissue
30	Specific Activity [micromol/min/mg]
11	Storage Stability
103	Substrates and Products (Substrate)
28	Subunits
98	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]
3	Temperature Stability [°C]
29	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 2.4.2.10 - orotate phosphoribosyltransferase

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6 - 380000

5-phospho-alpha-D-ribose 1-diphosphate

5 entries

diphosphate

Mycobacterium tuberculosis

P9WHK9

ping-pong mechanism, pH 8.0, 25°C

723161

60 - 358072

Orotate

5 entries

0.26 - 0.44

Orotidine

2 entries

4.8 - 530

orotidine 5'-phosphate

5 entries