2.4.1.88: globoside alpha-N-acetylgalactosaminyltransferase

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For detailed information about globoside alpha-N-acetylgalactosaminyltransferase, go to the full flat file.

Reaction

Synonyms

acetylgalactosaminyltransferase, uridine diphosphoacetylgalactosamine-globoside alpha-, cis-AB-transferase, Forss-S, Forssman synthase, Forssman synthetase, Forssmann glycolipid synthetase, FS, GBGT1, globoside acetylgalactosaminyltransferase, globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, glycosyltransferase 6 (GT6) family member, GT6m5, GT6m6, GT6m7, histo-blood group ABO system transferase, More, uridine diphosphoacetylgalactosamine-globoside alpha-acetylgalactosaminyltransferase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.88 globoside alpha-N-acetylgalactosaminyltransferase

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Results	in table
15	Activating Compound
9	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
1	Crystallization (Commentary)
10	Disease/ Diagnostics
2	Expression
4	General Information
4	General Stability
34	Inhibitors
1	Ki Value [mM]
6	KM Value [mM]
8	Localization
16	Metals/Ions
7	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
19	Organism
3	Pathway
6	pH Optimum
1	pH Range
2	Protein Variants
2	Purification (Commentary)
2	Reaction
1	Reaction Type
16	Reference
24	Source Tissue
5	Specific Activity [micromol/min/mg]
3	Storage Stability
24	Substrates and Products (Substrate)
2	Subunits
30	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]

Disease

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Disease on EC 2.4.1.88 - globoside alpha-N-acetylgalactosaminyltransferase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Aggressive Periodontitis

Molecular Evolution of the Glycosyltransferase 6 Gene Family in Primates.

28044107

Celiac Disease

Exome sequencing in a family segregating for celiac disease.

21627641

Colitis, Ulcerative

Mucosal genome-wide methylation changes in inflammatory bowel disease.

22419656

Crohn Disease

Mucosal genome-wide methylation changes in inflammatory bowel disease.

22419656

Ovarian Neoplasms

Expression of GBGT1 is epigenetically regulated by DNA methylation in ovarian cancer cells.

25294702

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