2.4.1.86: N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase

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For detailed information about N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase, go to the full flat file.

Reaction

Synonyms

beta1,4GalT-4, galactosyltransferase, uridine diphosphogalactose-acetyl-glucosaminylgalactosylglucosylceramide, GalT-4, glucosaminylgalactosylglucosylceramide beta-galactosyltransferase, LcOseCer:GT, N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferaselceramide beta-galactosyltransferase, paragloboside synthase, UDP-Gal:LcOse3Cer beta1,4-galactosyltransferase, UDP-galactose:N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide 3-beta-D-galactosyltransferase, UDPgalactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.86 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase

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Results	in table
2	Activating Compound
13	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
1	General Stability
2	Inhibitors
7	KM Value [mM]
2	Localization
8	Metals/Ions
3	Natural Substrates/ Products (Substrates)
6	Organism
6	Pathway
3	pH Optimum
4	Purification (Commentary)
1	Reaction
1	Reaction Type
6	Reference
8	Source Tissue
1	Specific Activity [micromol/min/mg]
10	Substrates and Products (Substrate)
11	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 2.4.1.86 - N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase

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SYSTEMATIC NAME

IUBMB Comments

UDP-alpha-D-galactose:N-acetyl-beta-D-glucosaminyl-R 3-beta-D-galactosyltransferase

The enzyme transfers galactose from UDP-alpha-D-galactose to the 3-position of substrates with a non-reducing terminal N-acetyl-beta-D-glucosamine (beta-GlcNAc) residue. It can act on both glycolipids and glycoproteins, generating a structure known as the type 1 histo-blood group antigen precursor.