2.4.1.66: procollagen glucosyltransferase

This is an abbreviated version!
For detailed information about procollagen glucosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.66

2.4.1.66

prolyl

gg

4-hydroxylase

galactosyltransferase

propeptide

soleus

aminoterminal

hyp

tibialis

4-hydroxyproline

chick-embryo

Reaction

[procollagen]-(5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysine

[procollagen]-(5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysine

Synonyms

collagen glucosyltransferase, collagen hydroxylysyl glucosyltransferase, galactosylhydroxylysine glucosyltransferase, galactosylhydroxylysyl glucosyltransferase, GGT, glucosyltransferase, uridine diphosphoglucose-collagen, LH3, LH3/PLOD3, lysyl hydroxylase, lysyl hydroxylase 3, More, multifunctional procollagen lysine hydroxylase and glycosyltransferase, PLOD3, UDP-glucose-collagen glucosyltransferase, UDP-glucose:galactosylhydroxylysine-collagen glucosyltransferase, uridine diphosphoglucose-collagen glucosyltransferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.66 procollagen glucosyltransferase

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Results	in table
5	Activating Compound
7	AA Sequence
1	CAS Registry Number
13	Cloned(Commentary)
2	Crystallization (Commentary)
131	Disease/ Diagnostics
4	Expression
11	General Information
12	General Stability
30	Inhibitors
2	Ki Value [mM]
30	KM Value [mM]
35	Localization
96	Metals/Ions
13	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
44	Organism
2	Pathway
7	PDB ID
12	pH Optimum
2	pH Range
1	pI Value
4	Posttranslational Modification
48	Protein Variants
45	Purification (Commentary)
6	Reaction
1	Reaction Type
44	Reference
97	Source Tissue
17	Specific Activity [micromol/min/mg]
10	Storage Stability
143	Substrates and Products (Substrate)
8	Subunits
42	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
2	Temperature Stability [°C]
1	Turnover Number [1/s]

General Stability

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General Stability on EC 2.4.1.66 - procollagen glucosyltransferase

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bovine serum albumin, final concentration of 0.1%, enhances stability

Homo sapiens

636786

chromatography on Biogel A-1.5M decreases stability

Homo sapiens

636787

concentrated enzyme, above 0.2 mg/ml, loses most of the activity

Gallus gallus

439149, 636783

extremely stable to freezing, -40°C, and thawing cycles, soluble enzyme

Homo sapiens

636787

loses activity during purification mostly due to inactivation

Gallus gallus

636780

stable in crude tissue extracts

5 entries

stable to repeated thawing and freezing, human liver or serum enzyme

Homo sapiens

439149