2.4.1.46: monogalactosyldiacylglycerol synthase
This is an abbreviated version!
For detailed information about monogalactosyldiacylglycerol synthase, go to the full flat file.
Word Map on EC 2.4.1.46
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2.4.1.46
-
chloroplast
-
galactolipids
-
digalactosyldiacylglycerol
-
thylakoid
-
plastid
-
phosphatidylglycerol
-
glycerolipids
-
type-b
-
extraplastidial
-
sulfoquinovosyldiacylglycerols
-
monotopic
-
monoglucosyldiacylglycerol
-
protochlorophyllide
-
de-epoxidase
- 2.4.1.46
- chloroplast
- galactolipids
- digalactosyldiacylglycerol
-
thylakoid
-
plastid
- phosphatidylglycerol
- glycerolipids
-
type-b
-
extraplastidial
- sulfoquinovosyldiacylglycerols
-
monotopic
- monoglucosyldiacylglycerol
- protochlorophyllide
-
de-epoxidase
Reaction
Synonyms
1,2-diacylglycerol 3-beta-galactosyltransferase, atMGD1, atMGD2, atMGD3, galactosyltransferase, uridine diphosphogalactose-1,2-diacylglycerol, LOC_Os02g55910, MGD, MGD1, MGD2, MGD3, MgdA, MGDG synthase, MGDG synthase 1, MGS, monogalactosyldiacylglycerol synthase, monogalactosyldiacylglycerol synthase 1, monogalactosyldiacylglycerol synthase A, monogalactosyldiacylglycerol synthase MGD1, monogalactosyldiacylglycerol synthase1, monoglucosyldiacylglycerol synthase, Os02g0802700, Sll1377, type A monogalactosyldiacylglycerol synthase, type B monogalactosyldiacylglycerol synthase, UDP galactose-1,2-diacylglycerol galactosyltransferase, UDP-galactose-diacylglyceride galactosyltransferase, UDP-galactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase, UDP-galactose:diacylglycerol galactosyltransferase, uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase
ECTree
2.4.1.46 monogalactosyldiacylglycerol synthaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 2.4.1.46 - monogalactosyldiacylglycerol synthase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
UDP-alpha-D-galactose + 1,2-dilinoleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dilinoleoylglycerol
-
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol
-
-
-
-
?
UDP-galactose + 1,2-dicaproylglycerol
UDP + 3-beta-D-galactosyl-1,2-dicaproylglycerol
-
-
-
?
UDP-galactose + 1,2-didecanoylglycerol
UDP + 3-beta-D-galactosyl-1,2-didecanoylglycerol
-
-
-
?
UDP-galactose + 1,2-dilauroylglycerol
UDP + 3-beta-D-galactosyl-1,2-dilauroylglycerol
-
-
-
?
UDP-galactose + 1,2-myristoylglycerol
UDP + 3-beta-D-galactosyl-1,2-myristoylglycerol
-
-
-
?
UDP-galactose + sn-1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoyl-sn-glycerol
-
-
-
?
UDP-galactose + sn-1-oleoyl-sn-2-palmitoyl-glycerol
UDP + 3-beta-D-galactosyl-sn-1-oleoyl-sn-2-palmitoyl-glycerol
-
-
-
?
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
-
?
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
-
ir
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
?
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
?
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
?
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
-
?
UDP-galactose + 1,2-diacyl-sn-glycerol
UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol
-
type B MGDG synthases may have roles during pollen germination and pollen tube growth and may be acting primarily to supply MGDG as a precursor for DGDG synthesis. Expression of atMGD2 and atMGD3, but not atMGD1, is strongly induced during phosphate starvation, particularly in roots
-
-
?
UDP-galactose + 1,2-diacyl-sn-glycerol
UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol
type B MGDG synthases may have roles during pollen germination and pollen tube growth and may be acting primarily to supply MGDG as a precursor for DGDG synthesis. Expression of atMGD2 and atMGD3, but not atMGD1, is strongly induced during phosphate starvation, particularly in roots
-
-
?
UDP-galactose + 1,2-diacyl-sn-glycerol
UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol
-
MGD activity is reversibly regulated by reduction and oxidation in vitro
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
requires the 1,2-isomer of the diglyceride substrate and prefers diglycerides with long-chain-saturated fatty acid constituents
i.e. 1,2-di-O-acyl-(beta-D-galactopyranosyl)-sn-glycerol
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
?
UDP-galactose + 1,2-dilinoleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dilinoleoylglycerol
-
-
?
UDP-galactose + 1,2-dilinoleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dilinoleoylglycerol
preferred substrate
-
?
UDP-galactose + 1,2-dilinoleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dilinoleoylglycerol
-
-
-
?
UDP-galactose + 1,2-dilinoleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dilinoleoylglycerol
-
-
-
?
UDP-galactose + 1,2-dilinoleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dilinoleoylglycerol
-
best substrate
-
?
UDP-galactose + 1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoylglycerol
-
-
?
UDP-galactose + 1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoylglycerol
-
-
-
?
UDP-galactose + 1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoylglycerol
-
-
-
?
UDP-galactose + 1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoylglycerol
-
-
-
?
UDP-galactose + 1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoylglycerol
-
-
-
?
UDP-galactose + 1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoylglycerol
-
-
-
-
?
UDP-galactose + 1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoylglycerol
-
-
-
?
UDP-galactose + 1,2-dipalmitoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dipalmitoylglycerol
-
-
-
?
UDP-galactose + 1,2-dipalmitoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dipalmitoylglycerol
-
-
-
?
UDP-galactose + 1,2-distearoylglycerol
UDP + 3-beta-D-galactosyl-1,2-distearoylglycerol
-
-
-
?
UDP-galactose + 1,2-distearoylglycerol
UDP + 3-beta-D-galactosyl-1,2-distearoylglycerol
-
-
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
last step in monogalactosyldiacylglycerol biosynthesis
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
last step in monogalactosyldiacylglycerol biosynthesis
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
last step in monogalactosyldiacylglycerol biosynthesis
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
enzyme is responsible for the biosynthesis of monogalactosyl diglyceride in brain and may function significantly in myelination
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
involved in biosynthesis of monogalactosyldiacylglycerol
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
last step in monogalactosyldiacylglycerol biosynthesis
-
?
additional information
?
-
-
MGDG synthase catalyzes the final step in thylakoid membrane lipid monogalactosyldiacylglycerol, MGDG, biosynthesis in the plastid envelope
-
-
?
additional information
?
-
-
mono- and digalactosyldiacylglycerol constitute the bulk of membrane lipids in plant chloroplasts and are essential for chloroplast biogenesis and photoautotrophic growth. Type B monogalactosyldiacylglycerol synthases are involved in phosphate starvation-induced lipid remodeling and are crucial for low-phosphate adaptation, overview
-
-
?
additional information
?
-
-
regulation of MGDGsynthesis by phosphatidic acid, which is a general precursor in the synthesis of all glycerolipids and is also a signaling molecule in plants
-
-
?
additional information
?
-
-
binding site for UDP-Gal lays in the cleft separating the two Rossmann folds involving residues of a conserved UDP-sugar binding pocket in the C-domain
-
-
?
additional information
?
-
reaction is proposed to to occur in a single displacement SN2 mechanism, with formation of an oxocarbenium ion transition state assisted by a catalytic base, H155. Phosphatidylglycerol binds to the active site where it is stabilized by interactions involving residues P189 and H155, creating an acid-base charge-relay system
-
-
-
additional information
?
-
-
in etiolated seedlings white light induces a transient increase in MGD mRNA, followed by a subsequent increase in enzyme activity. When cotyledons were detached from seedlings, these light-induced changes diminished
-
-
?
