2.4.1.40: glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase

This is an abbreviated version!
For detailed information about glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.40

2.4.1.40

acetoacetate

acetobutylicum

succinyl-coenzyme

3-oxoacids

2.8.3.5

solventogenesis

acetoacetyl-coenzyme

synthesis

Reaction

glycoprotein-alpha-L-fucosyl-(1->2)-D-galactose

glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-D-galactose

Synonyms

A transferase, A-transferase, ABO, ABO(H) blood group A glycosyltransferase, alpha-(1,3)-N-acetylgalactosaminyltransferase, alpha-3-N-acetylgalactosaminyltransferase, bacterial GTA, BgtA, blood group A glycosyltransferase, blood group A glycosyltransferase 2, blood-group substance A-dependent acetylgalactosaminyltransferase, blood-group substance alpha-acetyltransferase, cis-AB-transferase, fucosylgalactose acetylgalactosaminyltransferase, glycosyltransferases A, GTA, histo-blood group A acetylgalactosaminyltransferase, histo-blood group A glycosyltransferase (Fucalpha1-2Galalpha1-3-N-acetylgalactosaminyltransferase), histo-blood group A transferase, histo-blood group ABO system transferase, More, UDP-GalNAc:Fucalpha1-2Galalpha1-3-N-acetylgalactosaminyltransferase, UDP-N-acetyl-D-galactosamine:alpha-L-fucosyl-1,2-D-galactose 3-N-acetyl-D-galactosaminyltransferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.40 glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase

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Results	in table
34	AA Sequence
1	Application
1	CAS Registry Number
18	Cloned(Commentary)
13	Crystallization (Commentary)
74	Disease/ Diagnostics
2	General Information
3	General Stability
17	Inhibitors
3	Ki Value [mM]
36	KM Value [mM]
1	Localization
6	Metals/Ions
7	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
50	Organism
4	Pathway
119	PDB ID
9	pH Optimum
2	Posttranslational Modification
20	Protein Variants
9	Purification (Commentary)
1	Reaction
1	Reaction Type
49	Reference
50	Source Tissue
5	Specific Activity [micromol/min/mg]
8	Storage Stability
56	Substrates and Products (Substrate)
6	Subunits
33	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Stability [°C]
17	Turnover Number [1/s]

KM Value

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KM Value on EC 2.4.1.40 - glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase

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0.27 - 0.47

2'-fucosyllactose

3 entries

0.0099 - 0.4

alpha-Fuc-(1->2)-beta-D-Gal-(CH2)7CH3

6 entries

1.3

alpha-L-Fucp-(1,2)-beta-D-Galp-(1,3)-beta-DGlcNAcp-O(CH2)7CH3

Homo sapiens

P16442

37°C, pH 7.0

674703

0.49

alpha-L-Fucp-(1,2)-beta-D-Galp-(1,4)-beta-D-GlcNAcp-O-(CH2)8CO2CH3

Homo sapiens

P16442

37°C, pH 7.0

674703

0.087

alpha-L-Fucp-(1,2)-beta-D-Galp-O(CH2)7CH3

Homo sapiens

P16442

37°C, pH 7.0

674703

0.0087 - 0.167

L-fucosyl-alpha-1,2-beta-galactosyl-O(CH2)7CH3

4 entries

0.35

lacto-N-fucopentaose I

Homo sapiens

489162

0.02

octyl 3-O-methyl-alpha-L-fucopyranosyl-(1-2)-beta-D-galactopyranoside

Homo sapiens

489119

1.14

octyl 4-O-methyl-alpha-L-fucopyranosyl-(1-2)-beta-D-galactopyranoside

Homo sapiens

489119

0.208

octyl beta-D-arabinopyranosyl-(1-2)-beta-D-galactopyranoside

Homo sapiens

489119

0.0099 - 3.74

UDP-GalNAc

5 entries

0.242

UDP-GlcNAc

Homo sapiens

P16442

489114

0.0087 - 0.086

UDP-N-acetyl-alpha-D-galactosamine

7 entries

additional information

Homo sapiens

P16442

kinetics of recombinant wild-type GTA 53-354 and of GTA/GTB mutant chimeric enzymes

693025