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2.4.1.40: glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase

This is an abbreviated version!
For detailed information about glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.40

Reaction

UDP-N-acetyl-alpha-D-galactosamine
+
glycoprotein-alpha-L-fucosyl-(1->2)-D-galactose
=
UDP
 +
glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-D-galactose

Synonyms

A transferase, A-transferase, ABO, ABO(H) blood group A glycosyltransferase, alpha-(1,3)-N-acetylgalactosaminyltransferase, alpha-3-N-acetylgalactosaminyltransferase, bacterial GTA, BgtA, blood group A glycosyltransferase, blood group A glycosyltransferase 2, blood-group substance A-dependent acetylgalactosaminyltransferase, blood-group substance alpha-acetyltransferase, cis-AB-transferase, fucosylgalactose acetylgalactosaminyltransferase, glycosyltransferases A, GTA, histo-blood group A acetylgalactosaminyltransferase, histo-blood group A glycosyltransferase (Fucalpha1-2Galalpha1-3-N-acetylgalactosaminyltransferase), histo-blood group A transferase, histo-blood group ABO system transferase, More, UDP-GalNAc:Fucalpha1-2Galalpha1-3-N-acetylgalactosaminyltransferase, UDP-N-acetyl-D-galactosamine:alpha-L-fucosyl-1,2-D-galactose 3-N-acetyl-D-galactosaminyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.40 glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase

Disease

topprint

Disease on EC 2.4.1.40 - glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Breast Neoplasms
A sequencing strategy for the localization of O-glycosylation sites of MUC1 tandem repeats by PSD-MALDI mass spectrometry.
Carcinogenesis
UDP-GalNAc:Fuc alpha 1-2Gal alpha 1-3GalNAc transferase activity in hamster pancreatic cancers and in normal hamster alimentary tissues.
Carcinoma, Hepatocellular
Acetoacetate coenzyme A transferase activity in rat hepatomas.
Regulation of succinyl coenzyme A:acetoacetyl coenzyme A transferase in rat hepatoma cell lines.
Subcellular localization of acetoacetate coenzyme A transferase in rat hepatomas.
Galactosemias
Transferase-deficiency galactosemia: evidence for the lack of a transferase protein in galactosemic red cells.
glycoprotein-fucosylgalactoside alpha-n-acetylgalactosaminyltransferase deficiency
Prenatal diagnosis of succinyl-coenzyme A:3-ketoacid coenzyme A transferase deficiency.
Infections
Two glycosylation alterations of mouse intestinal mucins due to infection caused by the parasite Nippostrongylus brasiliensis.
Leukemia, Myeloid, Acute
Acute leukemia during pregnancy. Association with immune-mediated thrombocytopenia in mother and infant.
[A transient change in the blood group accompanied by the decreased activity of A transferase in a case of acute myeloid leukemia]
Lung Neoplasms
m6 A transferase METTL3-induced lncRNA ABHD11-AS1 promotes the Warburg effect of non-small-cell lung cancer.
Measles
Expression of ABO or related antigenic carbohydrates on viral envelopes leads to neutralization in the presence of serum containing specific natural antibodies and complement.
Migraine Disorders
Association of genetic loci for migraine susceptibility in the she people of China.
Myocardial Ischemia
Effect of chronic myocardial ischemia on the activity of carnitine palmitylcoenzyme A transferase of isolated canine heart mitochondria.
Neoplasms
3-Oxo acid coenzyme A transferase activity in brain and tumors of the nervous system.
ABH blood group antigen expression, synthesis, and degradation in human colonic adenocarcinoma cell lines.
Deletion of A-antigen in a human cancer cell line is associated with reduced promoter activity of CBF/NF-Y binding region, and possibly with enhanced DNA methylation of A transferase promoter.
Incompatible A antigen expressed in tumors of blood group O individuals: immunochemical, immunohistologic, and enzymatic characterization.
Loss of acetoacetate coenzyme A transferase activity in tumours of peripheral tissues.
Targeted breast cancer therapy by harnessing the inherent blood group antigen immune system.
UDP-GalNAc:Fuc alpha 1-2Gal alpha 1-3GalNAc transferase activity in hamster pancreatic cancers and in normal hamster alimentary tissues.
Nervous System Neoplasms
3-Oxo acid coenzyme A transferase activity in brain and tumors of the nervous system.
Pancreatic Neoplasms
UDP-GalNAc:Fuc alpha 1-2Gal alpha 1-3GalNAc transferase activity in hamster pancreatic cancers and in normal hamster alimentary tissues.
Parasitic Diseases
Blood group A glycosyltransferase occurring as alleles with high sequence difference is transiently induced during a Nippostrongylus brasiliensis parasite infection.
Phenylketonurias
When one disease is not enough: succinyl-CoA: 3-oxoacid coenzyme A transferase (SCOT) deficiency due to a novel mutation in OXCT1 in an infant with known phenylketonuria.
Stomach Neoplasms
Expression of human histo-blood group ABO genes is dependent upon DNA methylation of the promoter region.
m6 A transferase KIAA1429-stabilized LINC00958 accelerates gastric cancer aerobic glycolysis through targeting GLUT1.
Transcription starting from an alternative promoter leads to the expression of the human ABO histo-blood group antigen.
Tremor
Cryopreservation of spermatozoa from closed colonies, and inbred, spontaneous mutant, and transgenic strains of rats.
Tuberculosis
Potential mechanism of action of meso-dihydroguaiaretic acid on Mycobacterium tuberculosis H37Rv.