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2.4.1.39: steroid N-acetylglucosaminyltransferase

This is an abbreviated version!
For detailed information about steroid N-acetylglucosaminyltransferase, go to the full flat file.

Reaction

UDP-N-acetyl-alpha-D-glucosamine
+
estradiol-17alpha 3-D-glucuronoside
=
UDP
+
17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside

Synonyms

acetylglucosaminyltransferase, hydroxy steroid, hydroxy steroid acetylglucosaminyltransferase, steroid acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-steroid acetylglucosaminyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.39 steroid N-acetylglucosaminyltransferase

Substrates Products

Substrates Products on EC 2.4.1.39 - steroid N-acetylglucosaminyltransferase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
16,17-epiestriol-3-D-glucuronoside + UDP-N-acetylglucosamine
?
show the reaction diagram
-
-
-
-
?
16-epiestriol-3-D-glucuronoside + UDP-N-acetylglucosamine
UDP + 16-(N-acetyl-D-glucosaminyl)-epiestriol 3-D-glucuronoside
show the reaction diagram
-
-
-
?
17alpha-estradiol-3-D-glucuronoside + UDP-N-acetylglucosamine
UDP + 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside
show the reaction diagram
17alpha-estradiol-3-glucuronoside + UDP-N-acetylglucosamine
UDP + 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside
show the reaction diagram
-
-
-
?
additional information
?
-
-
high specificity for the 17alpha-hydroxyl group on phenolic steroids which are already attached through position 3 to glucosiduronic acid, overview
-
-
?