2.4.1.38: beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase

This is an abbreviated version!
For detailed information about beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.38

2.4.1.38

galts

galactosylate

synthesis

alpha-lactalbumin

p34cdc2-related

beta4galts

drug development

pharmacology

medicine

Reaction

N-acetyl-beta-D-glucosaminylglycopeptide

beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide

Synonyms

(alpha4Gal-T1), 4betaGalT, acetyllactosamine synthetase, alpha-1,4-galactosyltransferase I, B4GALT1, beta 1, 4-GalT-I, beta 1,4-galactosyltransferase 1, beta 1,4-GalT-I, beta 1,4GalT V, beta(1,4)-galactosyltransferase, beta(1,4)-GalT, beta(1,4)-GT, beta-1,4 galactosyltransferase I, beta-1,4 galactosyltransferase V, beta-1,4-galactosyltransferase, beta-1,4-galactosyltransferase 1, beta-1,4-galactosyltransferase I, beta-1,4-galactosyltransferase IV, beta-1,4-galactosyltransferase-I, beta-1,4-GalT, beta-1,4-GalT I, beta-1,4-GalT V, beta-1,4-GalT-I, beta-1,4-GalT5, beta-1,4-GalT6, beta-1,4-GalT7, beta-1,4-GT-IV, beta-N-acetyl-beta1-4-galactosyltransferase, beta-N-acetylglucosaminide beta1-4-galactosyltransferase, beta1,4-Gal-transferase T1, beta1,4-galactosyltransferase, beta1,4-galactosyltransferase 1, beta1,4-galactosyltransferase 7, beta1,4-galactosyltransferase I, beta1,4-galactosyltransferase II, beta1,4-galactosyltransferase V, beta1,4-galactosyltransferase-1, beta1,4-galactosyltransferase-I, beta1,4-galactosyltransferase1, beta1,4-GalT1, beta1,4-GalT7, beta1,4-GT, beta1,4-GT 1, beta1,4GalT II, beta1,4GT1, beta1-4-galactosyltransferase, beta1-4GalT, beta1-4GalT1, beta4 Gal-transferase, beta4-GalT-I, beta4-GalT-II, beta4-GalT-III, beta4-GalT-IV, beta4-GalT-V, beta4Gal-T1, beta4GalT, beta4GalT-II, beta4GalT1, beta4GalT7, betaGalT, betaGalT-1, betaGALT1, betaGT, EC 2.4.1.98, Gal-T, Gal-T1, galactosyltransferase 7, galactosyltransferase, uridine diphosphogalactose-acetylglucosamine, GalNAcT2, GALT, GalT I, GalT V, GalT1, GalTase, GalTI, glycoprotein 4-beta-galactosyl-transferase, glycoprotein beta-galactosyltransferase, HP0826, lactosamine synthase, lactosamine synthetase, lactose synthetase A protein, LgtB, LgtB-A, LgtB-B, LgtH, More, N-acetylglucosamine beta1,4 galactosyltransferase, N-acetyllactosamine synthetase, NAL synthetase, thyroid galactosyltransferase, thyroid glycoprotein beta-galactosyltransferase, UDP-beta-1,4-galactosyltransferase, UDP-Gal:betaGlcNAc beta-1,4-galactosyltransferase, polypeptide 1, UDP-Gal:N-acetylglucosamine beta1-4-galactosyltransferase, UDP-galactose N-acetylglucosamine beta-4-galactosyltransferase, UDP-galactose-acetylglucosamine galactosyltransferase, UDP-galactose-N-acetylglucosamine beta-1,4-galactosyltransferase, UDP-galactose-N-acetylglucosamine galactosyltransferase, UDP-galactose:N-acetylglucosaminide beta1-4-galactosyltransferase, UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase 2, UDPgalactose-glycoprotein galactosyltransferase, UDPgalactose-N-acetylglucosamine beta-D-galactosyltransferase, UDPgalactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase, UDPgalactose:N-acetylglucosaminyl(beta1-4)galactosyltransferase, uridine diphosphogalactose-acetylglucosamine galactosyltransferase, uridine diphosphogalactose-glycoprotein galactosyltransferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.38 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase

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Results	in table
37	Activating Compound
37	AA Sequence
9	Application
2	CAS Registry Number
44	Cloned(Commentary)
10	Crystallization (Commentary)
47	Disease/ Diagnostics
13	Expression
21	General Information
6	General Stability
4	IC50 Value
74	Inhibitors
23	kcat/KM [mM/s]
9	Ki Value [mM]
133	KM Value [mM]
76	Localization
68	Metals/Ions
23	Molecular Weight [Da]
55	Natural Substrates/ Products (Substrates)
149	Organism
10	Pathway
53	PDB ID
24	pH Optimum
2	pH Range
1	pH Stability
5	Posttranslational Modification
60	Protein Variants
35	Purification (Commentary)
7	Reaction
1	Reaction Type
145	Reference
3	Renatured (Commentary)
145	Source Tissue
17	Specific Activity [micromol/min/mg]
12	Storage Stability
271	Substrates and Products (Substrate)
24	Subunits
205	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]
51	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 2.4.1.38 - beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase

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106000

Homo sapiens

calculation from light-scattering experiments

29000

SDS-PAGE

38000

x * 38000, SDS-PAGE

42200

x * 42200, SDS-PAGE

42960

calculation from gene sequence, short form, transmembrane enzyme

43000

x * 43000, SDS-PAGE

440000

gel filtration

44420

long form with NH2-terminal extension of 13 amino acids, calculation from gene sequence

489498

44880

Bos taurus

unglycosylated enzyme, calculation from gene sequence

489505

47000

Homo sapiens

x * 47000, deglycosylated enzyme form, SDS-PAGE

489508

48000

Homo sapiens

x * 48000, glycosylated enzyme form

51000

x * 51000, SDS-PAGE

53000

x * 53000, SDS-PAGE

54000

x * 54000, enzyme from milk, SDS-PAGE

55000

2 * 55000, SDS-PAGE

57000

sucrose density gradient centrifugation

59000

gel filtration

70000

74000

1 * 74000, SDS-PAGE

85000 - 90000

gel filtration

additional information

Mus musculus

two related forms of enzyme of 399 and 386 amino acids are synthesized as a consequence of alternative translation initiation. The long enzyme form has a NH2-terminal extension of 13 amino acids

489498