2.4.1.37: fucosylgalactoside 3-alpha-galactosyltransferase

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For detailed information about fucosylgalactoside 3-alpha-galactosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.37

2.4.1.37

serological

udp-galnac

trisaccharide

abo-incompatible

galalpha1-3galbeta1-4glcnac-r

Reaction

alpha-D-galactosyl-(1->3)-[alpha-L-fucosyl(1->2)]-D-galactosyl-R

Synonyms

ABO(H) blood group B alpha-(1->3)-galactosyltransferase, ABO(H) blood group B alpha-1,3-galactosyltransferase, ABO(H) blood group B glycosyltransferase, ABO(H) blood-group glycosyltransferase B, alpha(1-3)galactosyltransferase, alpha-(1,3)-galactosyltransferase, alpha-(1-3)-galactosyltransferase, alpha-(1->3)-galactosyltransferase, alphaGal-T1, B glycosyltransferase, B transferase, blood group alpha-(1-3)-galactosyltransferase, blood group B alpha-(1,3)-galactosyltransferase, blood group B galactosyltransferase, blood group B glycosyltransferase, blood group B glycosyltransferase GTB, blood group B-glycosyltransferase, blood-group substance B-dependent galactosyltransferase, cis-AB-transferase, glycoprotein-fucosylgalactoside alpha-galactosyltransferase, glycosyltransferases B, GTB, histo-blood group ABO system transferase, histo-blood group B enzyme, histo-blood group B transferase, histo-blood substance B-dependent galactosyltransferase, More, UDP-galactose:fucoside alpha1,3-galactosyltransferase, UDP-galactose:O-alpha-L-fucosyl(1-2)D-galactose alpha-D-galactosyltransferase, UDPgalactose:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-alpha-D-galactosyltransferase, [blood group substance] alpha-galactosyltransferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.37 fucosylgalactoside 3-alpha-galactosyltransferase

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Results	in table
3	Activating Compound
87	AA Sequence
1	CAS Registry Number
24	Cloned(Commentary)
17	Crystallization (Commentary)
12	Disease/ Diagnostics
3	General Information
1	General Stability
12	IC50 Value
33	Inhibitors
7	Ki Value [mM]
91	KM Value [mM]
8	Localization
25	Metals/Ions
3	Molecular Weight [Da]
20	Natural Substrates/ Products (Substrates)
73	Organism
4	Pathway
121	PDB ID
16	pH Optimum
1	pI Value
50	Protein Variants
10	Purification (Commentary)
1	Reaction
1	Reaction Type
67	Reference
29	Source Tissue
11	Specific Activity [micromol/min/mg]
1	Storage Stability
112	Substrates and Products (Substrate)
5	Subunits
69	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
1	Temperature Stability [°C]
52	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 2.4.1.37 - fucosylgalactoside 3-alpha-galactosyltransferase

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2.11

1-(1-benzothiophen-3-yl)methanamine

Homo sapiens

pH 6.7, 37°C

719571

2.72

1-(2-chloro-6-fluorobenzyl)piperazine

Homo sapiens

pH 6.7, 37°C

719571

1.28

1-(3-methoxyphenyl)piperazine

Homo sapiens

pH 6.7, 37°C

719571

1.04

1-(3-phenyl-1,2,4-thiadiazol-5-yl)-1,4-diazepane

Homo sapiens

pH 6.7, 37°C

719571

0.79

1-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine

Homo sapiens

pH 6.7, 37°C

719571

2.16

1-methyl-1H-benzotriazole-5-carboxylic acid

Homo sapiens

pH 6.7, 37°C

719571

1.56

2,3-dimethylquinoxaline-6-carboxylic acid

Homo sapiens

pH 6.7, 37°C

719571

0.97

7-aminothieno[2,3-b]pyrazine-6-carboxylic acid

Homo sapiens

pH 6.7, 37°C

719571

1.9

9-(D-1-deoxy-arabinit-1-yl)-1,3,7-trihydropurine-2,6,8-trione

Homo sapiens

pH 7.0, 37°C

719291

1.2

9-D-ribityl-1,3,7-trihydropurine-2,6,8-trione

Homo sapiens

pH 7.0, 37°C

719291

2.61

N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine

Homo sapiens

pH 6.7, 37°C

719571

1.61

N-methyl-1-[3-(pyridin-4-yl)phenyl]methanamine

Homo sapiens

pH 6.7, 37°C

719571