2.4.1.337: 1,2-diacylglycerol 3-alpha-glucosyltransferase
This is an abbreviated version!
For detailed information about 1,2-diacylglycerol 3-alpha-glucosyltransferase, go to the full flat file.
Word Map on EC 2.4.1.337
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2.4.1.337
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acholeplasma
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bilayer
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laidlawii
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curvature
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nonbilayer-prone
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nonbilayer
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phosphatidylglycerol
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phospholipids
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liposome
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phosphatidylethanolamine
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lactose
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zwitterionic
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permease
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liquid-crystalline
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synthesis
- 2.4.1.337
- acholeplasma
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bilayer
- laidlawii
-
curvature
-
nonbilayer-prone
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nonbilayer
- phosphatidylglycerol
- phospholipids
- liposome
- phosphatidylethanolamine
- lactose
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zwitterionic
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permease
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liquid-crystalline
- synthesis
Reaction
Synonyms
alpha-monoglucosyldiacylglycerol synthase, Atu2297, EC 2.4.1.157, MGlcDAG synthase, MGS, UDP-glucose-diacylglycerol glucosyltransferase, UDP-glucose:1,2-diacyl-sn-glycerol 3-D-glucosyltransferase, UDP-glucose:1,2-diacylglycerol 3-D-glucosyltransferase, UDP-glucose:1,2-diacylglycerol glucosyltransferase, UDP-glucose:diacylglycerol glucosyltransferase, UgtP, uridine diphosphoglucose-diacylglycerol glucosyltransferase
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Substrates Products
Substrates Products on EC 2.4.1.337 - 1,2-diacylglycerol 3-alpha-glucosyltransferase
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REACTION DIAGRAM
UDP-alpha-D-glucose + 1,2-dioleoyl-sn-glycerol
UDP + 1,2-dioleoyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol
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?
UDP-alpha-D-glucose + 1,2-dipalmitoyl-sn-glycerol
UDP + 1,2-dipalmitoyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol
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?
UDP-alpha-D-glucose + a 1,2-diacyl-sn-glycerol
UDP + a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol
UDP-alpha-D-glucuronic acid + a 1,2-diacyl-sn-glycerol
UDP + a 1,2-diacyl-3-O-(alpha-D-glucuronosyl)-sn-glycerol
UDP-glucose + 1,2-dioleoylglycerol
UDP + 3-D-glucosyl-1,2-dioleoylglycerol
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?
UDPglucose + 1,2-dipalmitoylglycerol
UDP + 3-D-glucosyl-1,2-dipalmitoylglycerol
twice as high enzyme activity as sn-1,2-dioleoylglycerol at all concentrations up to 2.5 mol% concentration
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?
UDP + a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol
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?
UDP-alpha-D-glucose + a 1,2-diacyl-sn-glycerol
UDP + a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol
Agrobacterium tumefaciens ATCC 33970
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?
UDP + a 1,2-diacyl-3-O-(alpha-D-glucuronosyl)-sn-glycerol
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?
UDP-alpha-D-glucuronic acid + a 1,2-diacyl-sn-glycerol
UDP + a 1,2-diacyl-3-O-(alpha-D-glucuronosyl)-sn-glycerol
Agrobacterium tumefaciens ATCC 33970
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?
UDP + 3-D-glucosyl-1,2-diacylglycerol
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UDPglucose + 1,2-diacylglycerol
UDP + 3-D-glucosyl-1,2-diacylglycerol
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UDPglucose + 1,2-diacylglycerol
UDP + 3-D-glucosyl-1,2-diacylglycerol
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UDPglucose + 1,2-diacylglycerol
UDP + 3-D-glucosyl-1,2-diacylglycerol
the enzyme synthesizes the major nonbilayer-prone lipid monoglucosyldiacylglycerol in the membrane, which is important for spontaneous curvature, and is an important site for the lipid surface charge density
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?
UDPglucose + 1,2-diacylglycerol
UDP + 3-D-glucosyl-1,2-diacylglycerol
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the enzyme synthesizes the major nonbilayer-prone lipid monoglucosyldiacylglycerol in the membrane, which is important for spontaneous curvature, and is an important site for the lipid surface charge density
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?
UDPglucose + 1,2-diacylglycerol
UDP + 3-D-glucosyl-1,2-diacylglycerol
the product monoglucosyldiacylglycerol is the first glucolipid along the glucolipid pathway, and a major nonbilayer-prone lipid in the single membrane
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enzymic activity depends on the bilayer lipid environment. The activity depends on membrane binding per se but the enzyme must also adopt a certain conformation or orientation, and activity can be substantially modulated by interaction with various charged lipids or soluble molecules
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additional information
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enzymic activity depends on the bilayer lipid environment. The activity depends on membrane binding per se but the enzyme must also adopt a certain conformation or orientation, and activity can be substantially modulated by interaction with various charged lipids or soluble molecules
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additional information
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promiscuous glycosyltransferase, usues UDP-glucose or UDP-glucuronic acid as sugar donors
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additional information
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promiscuous glycosyltransferase, usues UDP-glucose or UDP-glucuronic acid as sugar donors
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additional information
?
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Agrobacterium tumefaciens ATCC 33970
promiscuous glycosyltransferase, usues UDP-glucose or UDP-glucuronic acid as sugar donors
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?