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2.4.1.327: aclacinomycin-T 2-deoxy-L-fucose transferase

This is an abbreviated version!
For detailed information about aclacinomycin-T 2-deoxy-L-fucose transferase, go to the full flat file.

Reaction

dTDP-2-deoxy-beta-L-fucose
+
aclacinomycin T
=
dTDP
+
aclacinomycin S

Synonyms

AknK, L-2-deoxyfucosyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.327 aclacinomycin-T 2-deoxy-L-fucose transferase

Systematic Name

Systematic Name on EC 2.4.1.327 - aclacinomycin-T 2-deoxy-L-fucose transferase

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SYSTEMATIC NAME
IUBMB Comments
dTDP-2-deoxy-beta-L-fucose:7-(alpha-L-rhodosaminyl)aklavinone 2-deoxy-alpha-L-fucosyltransferase
The enzyme, isolated from the bacterium Streptomyces galilaeus, is involved in the biosynthesis of other aclacinomycins. Also acts on idarubicin. It will slowly add a second 2-deoxy-L-fucose unit to aclacinomycin S in vitro.