2.4.1.316: tylactone mycaminosyltransferase
This is an abbreviated version!
For detailed information about tylactone mycaminosyltransferase, go to the full flat file.
Reaction
Synonyms
TylM2
ECTree
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Substrates Products
Substrates Products on EC 2.4.1.316 - tylactone mycaminosyltransferase
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REACTION DIAGRAM
tylactone + dTDP-D-desosaminose
dTDP + 5-O-desosaminyl-tylactone
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-
-
-
?
tylactone + dTDP-D-mycaminose
dTDP + 5-O-beta-D-mycaminosyltylactone
-
the product of gene tylM2 is the glycosyltansferase that adds mycaminose to the 5-hydroxyl group of tylactone
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-
?
dTDP + 5-O-beta-D-mycaminosyltylactone
the enzyme participates in the biosynthetic pathway of the macrolide antibiotic tylosin
-
-
?
tylactone + dTDP-alpha-D-mycaminose
dTDP + 5-O-beta-D-mycaminosyltylactone
the enzyme is flexible toward the acceptor substrate, glycosylating 16-membered tylactone and 12-membered ring macrolide
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-
?