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2.4.1.304: UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,4-galactosyltransferase

This is an abbreviated version!
For detailed information about UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,4-galactosyltransferase, go to the full flat file.

Reaction

UDP-alpha-D-galactose
+
N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
=
UDP
+
beta-D-Gal-(1->4)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol

Synonyms

UDP-Gal:GlcNAc-pyrophosphate-lipid beta-1,4-galactosyltransferase, UDP-Gal:GlcNAc-R 1,4-Gal-transferase, WfeD

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.304 UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,4-galactosyltransferase

Inhibitors

Inhibitors on EC 2.4.1.304 - UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,4-galactosyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4-hydroxyphenylglyoxal
-
0.2 mM, 50% inhibition
5,5'-dithio-bis-2-nitrobenzoic acid
-
0.2 mM, 85% inhibition
diethyl dicarbonate
-
0.2 mM 31% inhibition
Triton X-100
-
as the concentration of Triton X-100 increases from 0 to 0.5% in the reaction mixture, the activity of the enzyme decreases but is maintained at about 60% of the original activity, up to 6% Triton X-100