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2.4.1.289: N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase

This is an abbreviated version!
For detailed information about N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase, go to the full flat file.

Reaction

dTDP-6-deoxy-beta-L-mannose
+
N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
=
dTDP
+
alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol

Synonyms

cell wall rhamnosyltransferase, Cj1125c, dTDP-Rha:alpha-D-GlcNAc-pyrophosphate polyprenol, alpha-3-L-rhamnosyltransferase, lmo1080, PglA, RmlT, WbbL

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.289 N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase

Systematic Name

Systematic Name on EC 2.4.1.289 - N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase

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SYSTEMATIC NAME
IUBMB Comments
dTDP-6-deoxy-beta-L-mannose:N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol 3-alpha-L-rhamnosyltransferase
Requires Mn2+ or Mg2+. Isolated from Mycobacterium smegmatis [1] and Mycobacterium tuberculosis [2]. The enzyme catalyses the addition of a rhamnosyl unit to N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol, completing the synthesis of the linkage unit that attaches the arabinogalactan moiety to the peptidoglycan moiety in Mycobacterial cell wall.