2.4.1.288: galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferase

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For detailed information about galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.288

2.4.1.288

galactan

mycobacterial

tuberculosis

galf

polysaccharide

udp-galf

udp-galactofuranose

glycosyltransferases

arabinogalactan

glycoconjugate

mycolic

trisaccharide

tetrasaccharide

mycolyl-arabinogalactan-peptidoglycan

galactosyltransferase

polymerizing

l-arabinofuranose

galactomannans

anti-tuberculosis

fungal-type

Reaction

28 UDP-alpha-D-galactofuranose +

beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol

= 28 UDP +

[beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol

Synonyms

galactofuranosyl transferase 2, galactofuranosyltransferase, galactosyl transferase, GalTr, GlfT, GlfT2, LmjF.25.0010, LMJF_25_0010, LPG1, LPG1G, LPG1G2, LPG1L, Rv3808c

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.288 galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferase

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Results	in table
239	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
1	Crystallization (Commentary)
9	General Information
2	IC50 Value
13	Inhibitors
21	kcat/KM [mM/s]
1	Ki Value [mM]
30	KM Value [mM]
3	Metals/Ions
2	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
425	Organism
3	Pathway
17	Protein Variants
3	Purification (Commentary)
1	Reaction
25	Reference
13	Specific Activity [micromol/min/mg]
2	Storage Stability
65	Substrates and Products (Substrate)
4	Subunits
36	Synonyms
1	Systematic Name
30	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 2.4.1.288 - galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferase

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0.18

(2R,3R,4R,5R)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl hydrogen ((E)-((3R,4R,5S)-5-((R)-1,2-dihydroxyethyl)-3,4-dihydroxydihydrofuran-2(3H)-ylidene)fluoromethyl)phosphonate

Mycobacterium tuberculosis

O53585

pH not specified in the publication, temperature not specified in the publication

735959

0.55

(2R,3R,4R,5R)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl hydrogen ((Z)-((3R,4R,5S)-5-((R)-1,2-dihydroxyethyl)-3,4-dihydroxydihydrofuran-2(3H)-ylidene)fluoromethyl)phosphonate

Mycobacterium tuberculosis

O53585

pH not specified in the publication, temperature not specified in the publication

735959