2.4.1.278: 3-alpha-mycarosylerythronolide B desosaminyl transferase

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For detailed information about 3-alpha-mycarosylerythronolide B desosaminyl transferase, go to the full flat file.

Word Map on EC 2.4.1.278

2.4.1.278

erythromycin

saccharopolyspora

macrolide

erythraea

polyketide

glycosyltransferases

deoxysugars

d-desosamine

erythromycin-producing

macrolactone

peucetius

6-deoxyerythronolide

medicine

spinosyns

interspecies

14-membered

antibioticus

auxiliary

aglycone

Reaction

Synonyms

DesVII, EryCIII, glycosyltransferase EryCIII

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.278 3-alpha-mycarosylerythronolide B desosaminyl transferase

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Results	in table
97	AA Sequence
2	Application
2	Cloned(Commentary)
2	Cofactor
2	General Information
1	kcat/KM [mM/s]
1	KM Value [mM]
1	Natural Substrates/ Products (Substrates)
3	Organism
6	Pathway
1	pH Optimum
2	Purification (Commentary)
1	Reaction
3	Reference
1	Storage Stability
5	Substrates and Products (Substrate)
4	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
3	Turnover Number [1/s]

Turnover Number

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Turnover Number on EC 2.4.1.278 - 3-alpha-mycarosylerythronolide B desosaminyl transferase

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0.017 - 1.7

3-alpha-mycarosylerythronolide B

2 entries

1.7

dTDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose

Saccharopolyspora erythraea

pH 8.0, 25°C, in the presence og 0.001 mM EryC and 1 mM of each substrate, more than 300 turnovers are observed in 2.5 min, indicating that the kcat must be greater than 100/min. This is one of the highest turnover numbers reported for an antibiotic glycosyl transferase

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