2.4.1.275: neolactotriaosylceramide beta-1,4-galactosyltransferase

This is an abbreviated version!
For detailed information about neolactotriaosylceramide beta-1,4-galactosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.275

2.4.1.275

glycosphingolipids

laccer

d-pdmp

sphingolipids

glycolipids

ganglioside

d-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol

glct-1

galt-2

glucosyltransferase

hbecs

gm3

hemolytic-uremic

Reaction

N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

Synonyms

UDP-Gal:glucosylceramide beta1->4galactosyltransferase, beta-1,4-GalT IV, beta4Gal-T4, GalT-4, lactosylceramide synthase, lactotriaosylceramide:galactosyltransferase, LcOse3Cer:Gal-Tr, UDP-Gal:GLcNAcbeta1-3Galbeta1-4Glc-Cer beta1-4galactosyltransferase, UDP-Gal:Lc3 beta1-4galactosyltransferase, UDP-galactose:beta-N-acetylglucosamine beta1,4-galactosyltransferase, UDPGal:betaGlcNAc beta1,4Gal-transferase, uridine diphosphate-galactose:glucosyl ceramide, beta 1-4 galactosyltransferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.275 neolactotriaosylceramide beta-1,4-galactosyltransferase

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Results	in table
1	Activating Compound
16	AA Sequence
2	Cloned(Commentary)
2	General Information
2	General Stability
2	Inhibitors
4	KM Value [mM]
1	Localization
4	Metals/Ions
1	Natural Substrates/ Products (Substrates)
4	Organism
3	Pathway
1	pH Optimum
1	Purification (Commentary)
1	Reaction
4	Reference
13	Source Tissue
1	Specific Activity [micromol/min/mg]
18	Substrates and Products (Substrate)
13	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

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Reference on EC 2.4.1.275 - neolactotriaosylceramide beta-1,4-galactosyltransferase

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638234

Chou, D.K.H.; Jungalwala, F.B.

N-acetylglucosaminyl Transferase regulates the expression of sulfoglucuronyl glycolipids in specific cell types in cerebellum during development

J. Biol. Chem.

271

28868-28874

1996

Rattus norvegicus

8910533

715125

Guo, S.; Sato, T.; Shirane, K.; Furukawa, K.

Galactosylation of N-linked oligosaccharides by human beta-1,4-galactosyltransferases I, II, III, IV, V, and VI expressed in Sf-9 cells

Glycobiology

813-820

2001

Homo sapiens (O60513)

11588157

715137

Basu, M.; Weng, S.A.; Tang, H.; Khan, F.; Rossi, F.; Basu, S.

Biosynthesis in vitro of neolactotetraosylceramide by a galactosyltransferase from mouse T-lymphoma: purification and kinetic studies; synthesis of neolacto and polylactosamine core

Glycoconj. J.

423-432

1996

Mus musculus

8781973

715438

Schwientek, T.; Almeida, R.M., Levery, S.B.; Holmes, E.H.; Bennett, E.; Clausen, H.

Cloning of a novel member of the UDP-galactose:beta-N-acetylglucosamine beta1,4-galactosyltransferase family, beta4Gal-T4, involved in glycosphingolipid biosynthesis

J. Biol. Chem.

273

29331-29340

1998

Homo sapiens (O60513), Homo sapiens

9792633