2.4.1.274: glucosylceramide beta-1,4-galactosyltransferase
This is an abbreviated version!
For detailed information about glucosylceramide beta-1,4-galactosyltransferase, go to the full flat file.
Word Map on EC 2.4.1.274
Reaction
Synonyms
B4GalT5, B4GalT6, beta-1,4-galactosyltransferase V, beta-1,4-GalT-V, beta4-galactosyltransferase 5, beta4GalT5, Lac-Cer synthase, LacCer synthase, lactosylceramide synthase, UDP-Ga1:glucosylceramide beta1->4galactosyltransferase, UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase, UDP-galactose:GlcCer, beta1-4 galactosyltransferase, UDPgalactose:glucosylceramide beta1->4-galactosyltransferase
ECTree
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Reference on EC 2.4.1.274 - glucosylceramide beta-1,4-galactosyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Trinchera, M.; Fiorilli, A.; Ghidoni, R.
Localization in the Golgi apparatus of rat liver UDP-Gal:glucosylceramide beta1-4galactosyltransferase
Biochemistry
30
2719-2724
1991
Rattus norvegicus
Takizawa, M.; Nomura, T.; Wakisaka, E.; Yoshizuka, N.; Aoki, J.; Arai, H.; Inoue, K.; Hattori, M.; Matsuo, N.
cDNA cloning and expression of human lactosylceramide synthase
Biochim. Biophys. Acta
1438
301-304
1999
Homo sapiens (Q9UBX8)
Chatterjee, S.; Castiglione, E.
UDPgalactose:glucosylceramide beta1->4-galactosyltransferase activity in human proximal tubular cells from normal and familial hypercholesterolemic homozygotes
Biochim. Biophys. Acta
923
136-142
1987
Homo sapiens
Chatterjee, S.; Ghosh, N.; Khurana, S.
Purification of uridine diphosphate-galactose:glucosyl ceramide, beta1-4 galactosyltransferase from human kidney
J. Biol. Chem.
267
7148-7153
1992
Homo sapiens
Nomura, T.; Takizawa, M.; Aoki, J.; Arai, H.; Inoue, K.; Wakisaka, E.; Yoshizuka, N.; Imokawa, G., Dohmae, N.; Takio, K.; Hattori, M.; Matsuo, N.
Purification, cDNA cloning, and expression of UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase from rat brain
J. Biol. Chem.
273
13570-13577
1998
Rattus norvegicus
Kumagai, T.; Sato, T.; Natsuka, S.; Kobayashi, Y.; Zhou, D.; Shinkai, T.; Hayakawa, S.; Furukawa, K.
Involvement of murine beta-1,4-galactosyltransferase V in lactosylceramide biosynthesis
Glycoconj. J.
27
685-695
2010
Mus musculus
Tokuda, N.; Numata, S.; Li, X.; Nomura, T.; Takizawa, M.; Kondo, Y.; Yamashita, Y.; Hashimoto, N.; Kiyono, T.; Urano, T.; Furukawa, K.; Furukawa, K.
beta4GalT6 is involved in the synthesis of lactosylceramide with less intensity than beta4GalT5
Glycobiology
23
1175-1183
2013
Mus musculus, Mus musculus (Q9JMK0)
Shirane, K.; Kuji, R.; Tareyanagi, C.; Sato, T.; Kobayashi, Y.; Furukawa, S.; Murata, T.; Kubota, S.; Ishikawa, Y.; Segawa, K.; Furukawa, K.
Gene expression levels of beta4-galactosyltransferase 5 correlate with the tumorigenic potentials of B16-F10 mouse melanoma cells
Glycobiology
24
532-541
2014
Mus musculus (Q9JMK0)
Chatterjee, S.B.; Hou, J.; Bandaru, V.V.R.; Pezhouh, M.K.; Syed Rifat Mannan, A.A.; Sharma, R.
Lactosylceramide synthase beta-1,4-GalT-V A novel target for the diagnosis and therapy of human colorectal cancer
Biochem. Biophys. Res. Commun.
508
380-386
2019
Homo sapiens (O43286)
Yoshihara, T.; Satake, H.; Nishie, T.; Okino, N.; Hatta, T.; Otani, H.; Naruse, C.; Suzuki, H.; Sugihara, K.; Kamimura, E.; Tokuda, N.; Furukawa, K.; Fururkawa, K.; Ito, M.; Asano, M.
Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice
PLoS Genet.
14
e1007545
2018
Mus musculus (Q9JMK0), Mus musculus (Q9WVK5)
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