2.4.1.265: dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase

This is an abbreviated version!
For detailed information about dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase, go to the full flat file.

Reaction

alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol

alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol

Synonyms

ALG8, Dol-P-Glc:Glc1-Man9-GlcNAc2-P-P-Dol glucosyltransferase, dolichyl-P-Glc:Glc1 Man9GlcNAc2-PP-dolichyl alpha1,3-glucosyltransferase, dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl alpha1,3-glucosyltransferase, dolichyl-P-glucose:Glc1Man9GlcNAc2-PP-dolichyl alpha3-glucosyltransferase, hALG8, hALG8p

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.265 dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
90	AA Sequence
1	Application
2	Cloned(Commentary)
4	Disease/ Diagnostics
9	General Information
2	Localization
2	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
10	Organism
5	Pathway
4	Protein Variants
1	Reaction
10	Reference
1	Substrates and Products (Substrate)
1	Subunits
12	Synonyms
1	Systematic Name

Reference

top print

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Reference on EC 2.4.1.265 - dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase

Please use the Reference Search for a specific query.

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

708964

Runge, K.W.

Robbins, P.W.: A new yeast mutation in the glucosylation steps of the asparagine-linked glycosylation pathway. Formation of a novel asparagine-linked oligosaccharide containing two glucose residues

J. Biol. Chem.

261

15582-15590

1986

Saccharomyces cerevisiae (P40351)

3536907

708978

Chantret, I.; Dancourt, J.; Dupre, T.; Delenda, C.; Bucher, S.; Vuillaumier-Barrot, S.; Ogier de Baulny, H.; Peletan, C.; Danos, O.; Seta, N.; Durand, G.; Oriol, R.; Codogno, P.; Moore, S.E.

A deficiency in dolichyl-P-glucose:Glc1Man9GlcNAc2-PP-dolichyl alpha3-glucosyltransferase defines a new subtype of congenital disorders of glycosylation

J. Biol. Chem.

278

9962-9971

2003

Homo sapiens (Q9BVK2)

12480927

709391

Vesela, K.; Honzik, T.; Hansikova, H.; Haeuptle, M.A.; Semberova, J.; Stranak, Z.; Hennet, T.; Zeman, J.

A new case of ALG8 deficiency (CDG Ih)

J. Inherit. Metab. Dis.

259�264

2009

Homo sapiens

19688606

709484

Schollen, E.; Frank, C.G.; Keldermans, L.; Reyntjens, R.; Grubenmann, C.E.; Clayton, P.T.; Winchester, B.G.; Smeitink, J.; Wevers, R.A.; Aebi, M.; Hennet, T.; Matthijs, G.

Clinical and molecular features of three patients with congenital disorders of glycosylation type Ih (CDG-Ih) (ALG8 deficiency)

J. Med. Genet.

550-556

2004

Homo sapiens (Q9BVK2)

15235028

709971

St�lting, T.; Omran, H.; Erlekotte, A.; Denecke, J.; Reunert, J.; Marquardt, T.

Novel ALG8 mutations expand the clinical spectrum of congenital disorder of glycosylation type Ih

Mol. Genet. Metab.

305-309

2009

Homo sapiens (Q9BVK2), Homo sapiens

19648040

710441

Stagljar, I.; te Heesen, S.; Aebi, M.

New phenotype of mutations deficient in glucosylation of the lipid-linked oligosaccharide: cloning of the ALG8 locus

Proc. Natl. Acad. Sci. USA

5977-5981

1994

Saccharomyces cerevisiae (P40351)

8016100

722890

Diaz-Barrera, A.; Soto, E.; Altamirano, C.

Alginate production and alg8 gene expression by Azotobacter vinelandii in continuous cultures

J. Ind. Microbiol. Biotechnol.

613-621

2012

Azotobacter vinelandii

22072437

735487

Rehman, Z.U.; Wang, Y.; Moradali, M.F.; Hay, I.D.; Rehm, B.H.

Insights into the assembly of the alginate biosynthesis machinery in Pseudomonas aeruginosa

Appl. Environ. Microbiol.

3264-3272

2013

Pseudomonas aeruginosa

23503314

736726

Fata Moradali, M.; Donati, I.; Sims, I.; Ghods, S.; Rehm, B.

Alginate polymerization and modification are linked in Pseudomonas aeruginosa

mBio

1-17

2015

Pseudomonas aeruginosa, Pseudomonas aeruginosa PDO300

25968647