2.4.1.264: D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphosphoundecaprenol 2-beta-glucuronosyltransferase
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For detailed information about D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphosphoundecaprenol 2-beta-glucuronosyltransferase, go to the full flat file.
Reaction
Synonyms
gumK
ECTree
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Engineering
Engineering on EC 2.4.1.264 - D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphosphoundecaprenol 2-beta-glucuronosyltransferase
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D207A
mutation in UDP binding site, kcat/Km for UDP-glucuronate is identical to wild-type value
D234A
mutation in UDP binding site, kcat/Km for UDP-glucuronate is identical to wild-type value
E192A
mutation in UDP binding site, kcat/Km for UDP-glucuronate is identical to wild-type value
E272A
mutation in UDP binding site, kcat/KM is 4.6fold lower than wild-type value
E272D
mutation in UDP binding site, kcat/KM is 2fold lower than wild-type value
K307A
mutation in UDP binding site, kcat/KM is 560fold lower than wild-type value
M231A
mutation in UDP binding site, kcat/Km for UDP-glucuronate is similar to wild-type value
Q310A
mutation in UDP binding site, kcat/KM is 22.2fold lower than wild-type value
Y292A
mutation in UDP binding site, kcat/KM is 14.7fold lower than wild-type value