2.4.1.255: protein O-GlcNAc transferase
This is an abbreviated version!
For detailed information about protein O-GlcNAc transferase, go to the full flat file.
Word Map on EC 2.4.1.255
Reaction
Synonyms
beta-N-acetylglucosaminidase, EGF domain-specific O-GlcNAc transferase, EGF domain-specific O-linked N-acetylglucosamine transferase, EOGT, EOGT1, epidermal growth factor domain-specific O-GlcNAc transferase, glycosyltransferase OGT, Gtf1, GtfA, hOGT, HsOGT, human OGT, mammalian OGT, mOGT, More, N-acetylglucosamine transferase, N-acetylglucosamine-peptide N-acetylglucosaminyltransferase, N-acetylglucosaminyltransferase, ncOGT, nuclear cytoplasmic OGT, nucleocytoplasmic glycosyltransferase, nucleocytoplasmic OGT, O-GlcNAc protein, O-GlcNAc transferase, O-GlcNAc transferase OGT, O-GlcNAc-transferase, O-GlcNAcase, O-glycosylated protein p135, O-linked beta-N-acetylglucosamine transferase, O-linked beta-N-acetylglucosaminyltransferase, O-linked GlcNAc transferase, O-linked N-acetylglucosamine transferase, O-linked N-acetylglucosaminyltransferase, O-N-acetylglucosamine (O-GlcNAc) transferase, OGT, OGT p110, OGT protein, ogta, OGTase, OGTase protein, ogtb, p135, Protein SECRET AGENT, SEC, SECRET AGENT, sOGT, spindly, SPY, super sex combs, Sxc, Synpcc7942_0051, transferase OGT, UDP-GlcNAc: polypeptide O-N-acetylglucosaminyltransferase, UDP-GlcNAc:polypeptidyl transferase, UDP-N-acetylglucosaminyl transferase, uridine diphosphate-N-acetyl-D-glucosamine:polypeptidyltransferase, uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylaminyltransferase, uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase, XcOGT, XcOGT protein
ECTree
2.4.1.255 protein O-GlcNAc transferaseAdvanced search results
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results (IC50 Value
IC50 Value on EC 2.4.1.255 - protein O-GlcNAc transferase
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IC50 VALUE [mM] 
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.03 - 0.053
(2Z)-2-[(4-chlorophenyl)imino]-4-oxo-3-(2-tricyclo[3.3.1.1(3,7)]dec-1-ylethyl)-1,3-thiazinane-6-carboxylic acid
1.001
1-(4-acetamidophenyl)-4-(diphenylhydroxymethyl)-1H-1,2,3-triazole
Homo sapiens
pH 7.4, 37°C
0.0667
1-(4-acetamidophenyl)-4-(naphthalen-2-yl)-1H-1,2,3-triazole
Homo sapiens
pH 7.4, 37°C
0.139
1-(4-acetamidophenyl)-4-([1,1'-biphenyl]-4-yl)-1H-1,2,3-triazole
Homo sapiens
pH 7.4, 37°C
0.0893
1-(4-chloroacetamidophenyl)-4-(diphenylhydroxymethyl)-1H-1,2,3-triazole
Homo sapiens
pH 7.4, 37°C
0.0717
1-(4-chloroacetamidophenyl)-4-(naphthalen-2-yl)-1H-1,2,3-triazole
Homo sapiens
pH 7.4, 37°C
0.0912
1-(4-chloroacetamidophenyl)-4-([1,1'-biphenyl]-4-yl)-1H-1,2,3-triazole
Homo sapiens
pH 7.4, 37°C
0.018
2,4,5,6-tetraoxypyrimidine
Homo sapiens
pH and temperature not specified in the publication
0.053
3-(2-adamantanylethyl)-2-[(4-chlorophenyl)azamethylene]-4-oxo-1,3-thiazaperhydroine-6-carboxylic acid
Homo sapiens
pH and temperature not specified in the publication
0.06
3-(4-cyanobenzylthio)-1-(thiophen-2-yl)-5,6,7,8-tetrahydroisoquinoline-4-carboxylic acid
Homo sapiens
-
sOGT
0.01
4-methoxyphenyl 6-acetyl-2-oxobenzo[d]oxazole-3(2H)-carboxylate
Homo sapiens
pH and temperature not specified in the publication
2.218
5'-O-(hydroxy[3-[(2R,3R)-3-hydroxypyrrolidin-2-yl]propyl]phosphoryl)uridine
Homo sapiens
pH and temperature not specified in the publication
1.814
5'-O-(hydroxy[3-[(2R,3R,4S,5R)-3,4,5-trihydroxypyrrolidin-2-yl]propyl]phosphoryl)uridine
Homo sapiens
pH and temperature not specified in the publication
0.102
5'-O-(hydroxy[3-[(2R,3R,4S,5R)-3,4,5-tris(benzyloxy)pyrrolidin-2-yl]propyl]phosphoryl)uridine
Homo sapiens
pH and temperature not specified in the publication
0.589
5'-O-[[(2-(N-acetyl-akoga-D-glucosaminopyranosyl)-2,3-dihydro-1H-1,2,3-triazol-4-yl)methyl](hydroxy)phosphoryl]uridine
Homo sapiens
pH and temperature not specified in the publication
0.231
5'-O-[[(2-(N-acetyl-beta-D-glucosaminopyranosyl)-2,3-dihydro-1H-1,2,3-triazol-4-yl)methyl](hydroxy)phosphoryl]uridine
Homo sapiens
pH and temperature not specified in the publication
1.048
5'-O-[[(2-alpha-D-glucopyranosyl-2,3-dihydro-1H-1,2,3-triazol-4-yl)methyl](hydroxy)phosphoryl]uridine
Homo sapiens
pH and temperature not specified in the publication
1.439
5'-O-[[(2-beta-D-glucopyranosyl-2,3-dihydro-1H-1,2,3-triazol-4-yl)methyl](hydroxy)phosphoryl]uridine
Homo sapiens
pH and temperature not specified in the publication
4.769
5'-O-[[3-(N-acetyl-alpha-D-glucosaminopyranosyl)propyl](hydroxy)phosphoryl]uridine
Homo sapiens
pH and temperature not specified in the publication
0.718
5'-O-[[3-[(2R,3R)-3-(benzyloxy)pyrrolidin-2-yl]propyl](hydroxy)phosphoryl]uridine
Homo sapiens
pH and temperature not specified in the publication
1.14
5'-O-[[3-[(2R,3S,4S)-3,4-bis(benzyloxy)pyrrolidin-2-yl]propyl](hydroxy)phosphoryl]uridine
Homo sapiens
pH and temperature not specified in the publication
1.804
5'-O-[[3-[(2R,3S,4S)-3,4-dihydroxypyrrolidin-2-yl]propyl](hydroxy)phosphoryl]uridine
Homo sapiens
pH and temperature not specified in the publication
5.452
5'-O-[[3-[(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]propyl](hydroxy)phosphoryl]uridine
Homo sapiens
pH and temperature not specified in the publication
additional information
3-(4-cyanobenzylthio)-1-(thiophen-2-yl)-5,6,7,8-tetrahydroisoquinoline-4-carboxylic acid
Homo sapiens
-
for ncOGT IC50 value is about 100-150 microM
0.03
(2Z)-2-[(4-chlorophenyl)imino]-4-oxo-3-(2-tricyclo[3.3.1.1(3,7)]dec-1-ylethyl)-1,3-thiazinane-6-carboxylic acid
Homo sapiens
-
sOGT
0.053
(2Z)-2-[(4-chlorophenyl)imino]-4-oxo-3-(2-tricyclo[3.3.1.1(3,7)]dec-1-ylethyl)-1,3-thiazinane-6-carboxylic acid
Homo sapiens
-
ncOGT
0.0683
UDP-S-GlcNAc
Drosophila melanogaster
pH 7.5, temperature not specified in the publication
