2.4.1.237: flavonol 7-O-beta-glucosyltransferase

This is an abbreviated version!
For detailed information about flavonol 7-O-beta-glucosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.237

2.4.1.237

thiolactomycin

flavonols

glucosylation

beta-ketoacyl-acp

mycolic

petals

condensing

flavanones

coumarins

7-hydroxyl

Reaction

Synonyms

F 7 GT, F7GT, flavonol 7-O-glucosyltransferase, GT2, NTGT2, Q7OGT, quercetin 7OGT, quercetin-7-O-GT, UDP-glucose:flavonoid 7-O-glucosyltransferase, UDP-glucose:flavonol 7-O-glucosyltransferase, UDPG:flavonol 7-O-glucosyltransferase, UGT71F1, UGT73A4

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.237 flavonol 7-O-beta-glucosyltransferase

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Results	in table
5	Activating Compound
31	AA Sequence
1	CAS Registry Number
4	Cloned(Commentary)
40	Inhibitors
20	KM Value [mM]
7	Metals/Ions
4	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
8	Organism
5	Pathway
14	pH Optimum
4	pI Value
5	Purification (Commentary)
2	Reaction
1	Reaction Type
8	Reference
16	Source Tissue
5	Specific Activity [micromol/min/mg]
4	Storage Stability
87	Substrates and Products (Substrate)
3	Subunits
17	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 2.4.1.237 - flavonol 7-O-beta-glucosyltransferase

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4,4'-diisothiocyanostilbene-2,2'-disulfonic acid

Beta vulgaris

0.01 mM, UGT71F1; 0.01 mM, UGT73A4

Ca2+

Co2+

Cu2+

diethyldicarbonate

5 mM, 98% inhibition with quercetin or gossypetin as substrate

dithioerythritol

EDTA

Fe2+

1 mM, 98% inhibition with quercetin as substrate

657428

Hg2+

Glebionis segetum

1 mM, 99% inhibition with quercetin as substrate

iodoacetamide

iodoacetate

KCl

Mg2+

Mn2+

N-ethylmaleimide

p-chloromercuribenzene sulfonic acid

Beta vulgaris

UGT71F1, 0.01mM, 22% inhibition; UGT73A4 activity is completely inhibited at 0.01mM

676370

p-chloromercuribenzoate

2 entries

p-hydroxymercuribenzoate

Glebionis segetum

strong, 0.1 mM, 99.3% inhibition with quercetin as substrate, 14 mM 2-mercaptoethanol protects and addition after 15 min also reduces the inhibitory effect

657428

Phenylmercuriacetate

2 entries

Zn2+

2 entries

additional information

Glebionis segetum

not inhibited by EDTA

657428