2.4.1.231: alpha,alpha-trehalose phosphorylase (configuration-retaining)
This is an abbreviated version!
For detailed information about alpha,alpha-trehalose phosphorylase (configuration-retaining), go to the full flat file.
Reaction
Synonyms
PoTPase, ScTPase, TP2, TP3, trehalose phosphorylase
ECTree
2.4.1.231 alpha,alpha-trehalose phosphorylase (configuration-retaining)Advanced search results
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results (Substrates Products
Substrates Products on EC 2.4.1.231 - alpha,alpha-trehalose phosphorylase (configuration-retaining)
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-dehydro-D-glucose + alpha-D-glucose 1-phosphate
? + phosphate
-
-
-
-
?
2-deoxy-D-glucose + alpha-D-glucose 1-phosphate
?
-
8% of the activity with alpha-D-glucose
-
-
r
2-fluoro-D-glucose + alpha-D-glucose 1-phosphate
?
-
15% of the activity with alpha-D-glucose
-
-
r
2-keto-D-glucose + alpha-D-glucose 1-phosphate
?
-
50% of the activity with alpha-D-glucose
-
-
r
alpha,alpha-trehalose + arsenate
alpha-D-glucose + alpha-D-glucose 1-arsenate
-
-
-
-
r
D-mannose + alpha-D-glucose 1-phosphate
?
-
3% of the activity with alpha-D-glucose
-
-
r
alpha,alpha-trehalose + arsenate
alpha-D-glucose 1-arsenate + alpha-D-glucose
-
30% of the activity with phosphate
-
-
?
alpha,alpha-trehalose + arsenate
alpha-D-glucose 1-arsenate + alpha-D-glucose
-
-
-
-
r
alpha,alpha-trehalose + arsenate
alpha-D-glucose 1-arsenate + alpha-D-glucose
-
-
alpha-D-glucose 1-arsenate is unstable, therefore the net reaction gives two mol of alpha-D-glucose
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
key role in trehalose metabolism
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
key role in trehalose metabolism
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
?
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
-
?
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
-
?
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
?
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
?
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
-
?
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
-
r
alpha,alpha-trehalose + phosphate
alpha-D-glucose + alpha-D-glucose 1-phosphate
-
-
reverse reaction only utilizes the alpha-anomers of D-glucose-1-phosphate and D-glucose and gives exclusively the alpha,alpha-product
r
alpha-D-glucose + alpha-D-glucose 1-phosphate
alpha,alpha-trehalose + phosphate
-
-
-
r
alpha-D-glucose + alpha-D-glucose 1-phosphate
alpha,alpha-trehalose + phosphate
-
beta-D-glucose 1-phosphate is not turned over by the enzyme
-
-
r
alpha-D-glucose + alpha-D-glucose 1-phosphate
alpha,alpha-trehalose + phosphate
-
-
-
r
alpha-D-glucose + alpha-D-glucose 1-phosphate
alpha,alpha-trehalose + phosphate
ratio of phosphorolysis to hydrolysis is 46000
-
-
r
alpha-D-glucose + alpha-D-glucose 1-phosphate
alpha,alpha-trehalose + phosphate
ratio of phosphorolysis to hydrolysis is 46000
-
-
r
alpha-D-glucose 1-fluoride + phosphate
alpha-D-glucose 1-phosphate + fluoride
-
-
-
-
?
alpha-D-glucose 1-fluoride + phosphate
alpha-D-glucose 1-phosphate + fluoride
-
poor substrate, alpha-D-glucose 1-fluoride is recognized as a substrate analogue of alpha,alpha-trehalose but not of alpha-D-glucose 1-phosphate
-
-
?
additional information
?
-
-
the enzyme is involved in trehalose catabolism
-
-
?
additional information
?
-
-
the maltose phosphorylase loop 3 variants TP2 and TP3 are capable of phosphorolysing trehalose (alpha, alpha1) as well as maltose (alpha-1,4),but show no activity towards kojibiose (alpha-1,2), nigerose (alpha-1,3) or isomaltose (alpha-1,6). The catalytic efficiency of TP3 towards trehalose is 19fold higher than of TP2
-
-
?
additional information
?
-
-
the maltose phosphorylase loop 3 variants TP2 and TP3 are capable of phosphorolysing trehalose (alpha, alpha1) as well as maltose (alpha-1,4),but show no activity towards kojibiose (alpha-1,2), nigerose (alpha-1,3) or isomaltose (alpha-1,6). The catalytic efficiency of TP3 towards trehalose is 19fold higher than of TP2
-
-
?
additional information
?
-
-
no measurable activity is found with D-arabinose, D-fructose, D-fucose, D-galactose, D-lyxose, D-mannoheptaose, D-ribose and D-xylose
-
-
?
additional information
?
-
during heat stress, trehalose phosphorylase shows reversible activity
-
-
-
