2.4.1.228: lactosylceramide 4-alpha-galactosyltransferase

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For detailed information about lactosylceramide 4-alpha-galactosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.228

2.4.1.228

glycosphingolipids

sphingolipids

gangliosides

lysosomal

gaucher

sphingomyelin

glycolipids

multidrug

glccer

sphingomyelinase

sphingosine

p-glycoprotein

gm3

d-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol

glucocerebrosidase

eliglustat

d-pdmp

niemann-pick

ceramide-induced

iminosugars

fabry

ceramidase

glucosylceramidase

shiga

nb-dnj

c6-ceramide

fumonisin

globo-series

dihydroceramide

1-phenyl-2-decanoylamino-3-morpholino-1-propanol

n-butyldeoxynojirimycin

gd1a

verotoxins

neuronopathic

medicine

Reaction

beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

Synonyms

A4GalT, alpha 1-4 galactosyltransferase, alpha1,4-galactosyltransferase, alpha1,4Gal-T, blood group P1 synthase, Gal-beta1-4Glcbeta1-Cer alpha1,4-galactosyltransferase, galactosyltransferase, uridine diphosphogalactose-lactosylceramide, galactosyltransferase, uridine diphosphogalactose-lactosylceramide alpha1-4-, Gb3 galactosyltransferase, GB3 synthase, Gb3/CD77 synthase, Gb3Cer synthase, Gb3S, GCS, globotetraosyl ceramide synthase, globotriaosylceramide synthase, globotriaosylceramide/CD77 synthase, glucosylceramide synthase, histo-blood group Pk antigen synthase, histo-blood group Pk UDP-galactose, lactosylceramide 4-alpha-galactosyltransferase, lactosylceramide alpha1,4-galactosyltransferase, lactosylceramide alpha1,4galactosyltransferase, Pk synthase, UDP-galactose-lactosylceramide galactosyltransferase, UDP-galactose:beta-D-galactosyl-beta-1-R 4-alpha-D-galactosyltransferase, UDP-galactose:lactosylceramide alpha-galactosyltransferase, UDP-galactose:lactosylceramide alpha1-4-galactosyltransferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.228 lactosylceramide 4-alpha-galactosyltransferase

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Results	in table
4	Activating Compound
29	AA Sequence
2	Application
1	CAS Registry Number
8	Cloned(Commentary)
652	Disease/ Diagnostics
2	Expression
14	General Information
5	Inhibitors
7	KM Value [mM]
8	Localization
10	Metals/Ions
4	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
24	Organism
4	Pathway
4	pH Optimum
1	pH Range
3	Protein Variants
3	Purification (Commentary)
1	Reaction
3	Reaction Type
24	Reference
38	Source Tissue
8	Specific Activity [micromol/min/mg]
4	Storage Stability
32	Substrates and Products (Substrate)
2	Subunits
50	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]

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Source Tissue on EC 2.4.1.228 - lactosylceramide 4-alpha-galactosyltransferase

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brain

Mus musculus

low, but definite, levels of Gb3/CD77 are expressed in the microvascular endothelial cells of the brain cortex

674524