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2.4.1.214: glycoprotein 3-alpha-L-fucosyltransferase

This is an abbreviated version!
For detailed information about glycoprotein 3-alpha-L-fucosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.214

Reaction

GDP-beta-L-fucose
+
N4-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc]-L-asparaginyl-[protein]
=
GDP
 +
N4-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc]-L-asparaginyl-[protein]

Synonyms

alpha 1,3-fucosyltransferase VI, alpha(1,3)-fucosyltransferase VII, alpha(1,3)-fucosyltransferase-IV, alpha(1,3)-fucosyltransferase-VII, alpha(1,3)fucosyltransferase, alpha-1,3-fucosyltransferase-VII, alpha1,3-fucosyltransferase, alpha1,3-fucosyltransferase 10, alpha1,3-fucosyltransferase 7, alpha1,3-fucosyltransferase 9, alpha1,3-fucosyltransferase IX, alpha1,3FTs, alpha1-3 fucosyltransferase-VII, alpha3-fucosyltransferase, alpha3-FucT VII, AtFUT11, CEFT-1, CEFT-2, CEFT-3, CEFT-4, CEFT-5, CEFT3, core alpha-(1,3)-fucosyltransferase, core alpha1,3-fucosyltransferase, Fuc-T C3, Fuc-TVII, fucosyltransferase A, fucosyltransferase VII, FucT, FucT 115, FucT 45, FucT VI, FucT VII, FucT-IV, FucT-VII, FucT1, FucTA, FucTB, FucTC, FUT-1, FUT-6, FUT10, FUT11, FUT7, Fut9, GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fuca1-6GlcNAc)-Asn-peptide) alpha1-3-fucosyltransferase, GDP-L-fuc:Asn-linked GlcNAc alpha1,3-fucosyltransferase, GDP-L-fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase, LOC107797347, LOC107830046, NM_001324945, XM_016620229, XM_016657530

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.214 glycoprotein 3-alpha-L-fucosyltransferase

Specific Activity

Specific Activity on EC 2.4.1.214 - glycoprotein 3-alpha-L-fucosyltransferase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.000001
-
LEC12 mutant, substrate: alpha1-acid glycoprotein
0.000002
-
LEC11 mutant with transferrin as substrate and LEC12 mutant with fetuin as substrate
0.000003
-
LEC12 mutant, substrate: transferrin
0.000007
-
LEC11 mutant, substrate: asialotransferrin
0.000013
-
LEC11 mutant, substrate: asialofetuin
0.000014
-
LEC11 mutant with fetuin as substrate and LEC12 mutant with asialofetuin as substrate
0.000015
-
LEC11 mutant, substrate: alpha1-acid glycoprotein
0.000016
-
LEC12 mutant, substrate: asialo-alpha1-acid glycoprotein or asialotransferrin
0.000019
-
LEC11 mutant, substrate: asialo-alpha1-acid glycoprotein
0.071
-
-
0.38
deletion mutant FTdelta115 with 115 residues deleted from the C-terminus, substrate LacNAc
1.6
-
purified recombinant soluble enzyme
2.52
deletion mutant FTdelta23 with 23 residues deleted from the C-terminus, substrate LacNAc
4.84
deletion mutant FTdelta28 with 28 residues deleted from the C-terminus, substrate LacNAc
43.35
-
-
5.04
deletion mutant FTdelta38 with 38 residues deleted from the C-terminus, substrate LacNAc
5.2
deletion mutant FTdelta80 with 80 residues deleted from the C-terminus, substrate LacNAc
5.72
deletion mutant FTdelta45 with 45 residues deleted from the C-terminus, substrate LacNAc
5.82
deletion mutant FTdelta66 with 66 residues deleted from the C-terminus, substrate LacNAc
additional information