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tetramer
mutant enzymes D159N, D162N and DELTA270-332/D162N exist as both tetrameric and dimeric species
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x * 60300, about, sequence calculation
dimer
truncation mutant enzymes DELTA270-332/D159S and DELTA270/D162S, wild-type enzyme in glycosylated and nonglycosylated form, full-length mutant enzymes D162S and D159S exists as more than 95% dimer. Mutant enzymes D159N, D162N and DELTA270-332/D162N exist as both tetrameric and dimeric species
dimer
2 * 34000, non-glycosylated truncated protein, 0.02 mM enzyme solution
dimer
2 * 38000, native enzyme
monomer
1 * 34000, non-glycosylated truncated protein, 0.0005 mM enzyme solution
monomer
1 * 38000, native enzyme, 50-70% of the activity of the dimer
additional information
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in muscle a glycogen beta-particle is bound to glycogenin in a 1:1 ratio, the enzyme/glycogen ratio in liver is lower
additional information
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enzyme forms the protein part of proteoglycogen
additional information
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glycogenin is a member of the GT8 family of glycosyltransferases with a GT-A architecture containing an N-terminal catalytic domain with a single Rossmann fold that operates as an obligate dimer. The core catalytic domain is followed by a C-terminal extension of variable length and undefined structure. Oligomerization of glycogenin and glycogen synthase from Caenorhabditis elegans enhances binding through an avidity effect
additional information
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enzyme forms the protein part of proteoglycogen
additional information
hGYG1 ccurs in two distinct states, the ground state and the active state, the two states are interchangeable during catalysis and involve conformational rearrangements in three regions that influence active site accessibility, overview
additional information
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hGYG1 ccurs in two distinct states, the ground state and the active state, the two states are interchangeable during catalysis and involve conformational rearrangements in three regions that influence active site accessibility, overview
additional information
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enzyme forms the protein part of proteoglycogen
additional information
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in muscle a glycogen beta-particle is bound to glycogenin in a 1:1 ratio, the enzyme/glycogen ratio in liver is lower
additional information
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enzyme forms the protein part of proteoglycogen
additional information
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enzyme forms the protein part of proteoglycogen
additional information
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glycogenin glucosyltransferase, MW 38 kDa, represents the smaller subunit of glycogen synthase, both enzyme form a heterodimeric complex of molar ratio 1:1
additional information
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glycogenin glucosyltransferase, MW 38 kDa, represents the smaller subunit of glycogen synthase, both enzyme form a heterodimeric complex of molar ratio 1:1
additional information
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glycogenin glucosyltransferase, MW 38 kDa, represents the smaller subunit of glycogen synthase, both enzyme form a heterodimeric complex of molar ratio 1:1
additional information
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purified glycogenin associates as a dimer in absence of SDS, MW 64 kDa, glycerol density gradient centrifugation
additional information
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in muscle a glycogen beta-particle is bound to glycogenin in a 1:1 ratio, the enzyme/glycogen ratio in liver is lower
additional information
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enzyme forms the protein part of proteoglycogen
additional information
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glycogenin glucosyltransferase, MW 38 kDa, represents the smaller subunit of glycogen synthase, both enzyme form a heterodimeric complex of molar ratio 1:1