2.4.1.180: lipopolysaccharide N-acetylmannosaminouronosyltransferase
This is an abbreviated version!
For detailed information about lipopolysaccharide N-acetylmannosaminouronosyltransferase, go to the full flat file.
Reaction
Synonyms
ManNAcA transferase, ManNAcA-transferase, teichuronic acid synthetase, TUAS, uridine diphosphoacetylmannosaminuronate-acetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminuronosyltransferase
ECTree
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General Information
General Information on EC 2.4.1.180 - lipopolysaccharide N-acetylmannosaminouronosyltransferase
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additional information
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the 440 kDa enzyme complex, named teichuronic acid synthetase, TUAS, is an octomer composed of two kinds of glycosyltransferases, glucosyltransferase, and ManNAcA-transferase, which is capable of catalyzing the transfer of disaccharide glycosyl residues containing both glucose and the N-acetylmannosaminuronic acid residues. TUAS is a bifunctional glycosyltransferase capable of transferring both the component sugars, glucose and ManNAcA, for the TUA polymer. The purified TUAS contains carotinoids and lipids. TUAS serves as a multitasking polysaccharide assembling station on the bacterial membrane