2.4.1.179: lactosylceramide beta-1,3-galactosyltransferase

This is an abbreviated version!
For detailed information about lactosylceramide beta-1,3-galactosyltransferase, go to the full flat file.

Reaction

beta-D-galactosyl-(1->4)-beta-D-glucosyl-R

beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R

Synonyms

galactosyltransferase, uridine diphosphogalactose-lactosylceramide beta1-3-, GalT2, UDP-Gal:GA2/GM2/GD2 beta-1,3-galactosyltransferase, UDP-galactose:lactose beta1,3-galactosyltransferase, uridine diphosphogalactose-lactosylceramide beta1-3-galactosyltransferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.179 lactosylceramide beta-1,3-galactosyltransferase

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Results	in table
10	Activating Compound
1	CAS Registry Number
2	Cloned(Commentary)
2	General Stability
4	Inhibitors
6	KM Value [mM]
8	Localization
10	Metals/Ions
6	Natural Substrates/ Products (Substrates)
8	Organism
6	pH Optimum
3	pH Range
3	Purification (Commentary)
2	Reaction
1	Reaction Type
8	Reference
13	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
45	Substrates and Products (Substrate)
5	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
2	Temperature Stability [°C]

Activating Compound

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Activating Compound on EC 2.4.1.179 - lactosylceramide beta-1,3-galactosyltransferase

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Bovine liver non-specific transfer proteins

Homo sapiens

activation

638380

CHAPSO

Homo sapiens

5 to 7fold less effective compared to Triton CF-54

638380

deoxycholate

Homo sapiens

5 to 7fold less effective compared to Triton CF-54

638380

glycerol

Homo sapiens

requirement, above 20% w/v

638376

phosphatidylethanolamine

Homo sapiens

activation, less efficient than Triton CF-54

638380

taurodeoxycholate

Homo sapiens

5 to 7fold less effective compared to Triton CF-54

638380

Triton CF-54

2 entries

Triton X-100

Homo sapiens

activation, can replace Triton CF-54 with 75% less efficiency

638380

additional information

Homo sapiens

little or no activation by phosphatidylcholine, phosphatidylglycerol, phosphatidylserine, phosphatidylinositol or cardiolipin, Brij-58, Empigen BB or detergent G-3634-A

638380