2.4.1.173: sterol 3beta-glucosyltransferase

This is an abbreviated version!
For detailed information about sterol 3beta-glucosyltransferase, go to the full flat file.

Reaction

Synonyms

Atg26, AtSGT, autophagy-related protein 26, CG synthetase, pUGT51, ScAtg26, SGT, SGT1, SGT2, SGT3, SGT4, SGTL1, SgtL2, SgtL4, SlSGT1, SlSGT2, SlSGT3, SlSGT4, Solyc04g051150.2.1, Solyc04g071540.2.1, Solyc06g007980.2.1, Solyc09g061860.2.1, sterol glucosyltransferase, sterol glucosyltransferase Ugt51/Paz4, sterol glycosyltransferase, sterol-beta-D-glucosyltransferase, sterol:UDPG glucosyltransferase, UDP-Glc:sterol glucosyltransferase 80B1, UDP-glucose sterol glucosyltransferase, UDP-glucose sterol glycosyltransferase, UDP-glucose-sterol beta-glucosyltransferase, UDP-glucose-sterol glucosyltransferase, UDP-glucose:sterol glucosyltransferase, UDP-glycosyltransferase 51, UDPG-SGTase, UDPG:sterol glucosyltransferase, UDPglucose:sterol glucosyltransferase, Ugt51, Ugt51/Paz4, ugt51E1, UGT713B1, UGT80A2, UGT80B1, uridine diphosphoglucose-poriferasterol glucosyltransferase, uridine diphosphoglucose-sterol glucosyltransferase, USGT80B1

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.173 sterol 3beta-glucosyltransferase

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Results	in table
48	Activating Compound
1416	AA Sequence
4	Application
2	CAS Registry Number
31	Cloned(Commentary)
1	Crystallization (Commentary)
5	Disease/ Diagnostics
5	Expression
47	General Information
8	IC50 Value
71	Inhibitors
3	kcat/KM [mM/s]
2	Ki Value [mM]
51	KM Value [mM]
53	Localization
32	Metals/Ions
15	Molecular Weight [Da]
31	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
99	Organism
2	Pathway
4	PDB ID
16	pH Optimum
2	pH Range
23	pH Stability
1	pI Value
22	Protein Variants
25	Purification (Commentary)
1	Reaction
1	Reaction Type
73	Reference
68	Source Tissue
3	Specific Activity [micromol/min/mg]
3	Storage Stability
268	Substrates and Products (Substrate)
10	Subunits
110	Synonyms
1	Systematic Name
31	Temperature Optimum [°C]
1	Temperature Range [°C]
11	Turnover Number [1/s]

KM Value

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KM Value on EC 2.4.1.173 - sterol 3beta-glucosyltransferase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.024

24-methylene cholesterol

Withania somnifera

-

for the cytosolic enzyme

672427

0.006

3-beta-hydroxy-pregna-5,16-dien-20-one

Withania somnifera

-

for the cytosolic enzyme

672427

0.017

3beta-hydroxy-16,17-alpha-epoxypregnenolene

Arabidopsis thaliana

-

-

671624

0.01

3beta-hydroxy-16,17alpha-epoxypregnenolone

Withania somnifera

Q2I015

activity is assayed radiometrically using UDP-[U-14C] glucose, at pH 8.0 and 37°C

671624

0.007

3beta-hydroxy-pregna-5,16-dien-20-one

Arabidopsis thaliana

-

-

671624

0.01

3beta-hydroxy-pregna-5,16-dien-one

Withania somnifera

Q2I015

activity is assayed radiometrically using UDP-[U-14C] glucose, at pH 8.0 and 37°C

671624

0.063

5alpha-Cholestan-3beta-ol

Arabidopsis thaliana

-

-

671624

0.005 - 0.059

beta-sitosterol

3 entries

0.0045 - 0.03

brassicasterol

2 entries

0.056 - 0.0672

cholesterol

3 entries

0.04 - 0.119

dehydroepiandrosterone

3 entries

0.002

diosgenin

Withania somnifera

-

for the cytosolic enzyme

672427

0.004 - 0.035

ergosterol

2 entries

0.0048

poriferasterol

Physarum polycephalum

-

-

637767

0.005 - 0.008

pregnenolone

3 entries

0.005 - 0.54

sitosterol

5 entries

0.003 - 0.007

solasodine

2 entries

0.00143

stigmast-5-en-3beta-ol

Solanum melongena

-

pH 7,3, 30°C

690224

0.027 - 0.125

stigmasterol

3 entries

0.8379

testosterone

Ogataea angusta

A7KAK6

pH 7.8, 30°C

736786

0.025 - 0.059

transandrosterone

2 entries

0.008 - 0.34

UDP-glucose

12 entries

0.005

beta-sitosterol

Withania somnifera

-

for the cytosolic enzyme

672427

0.04

beta-sitosterol

Withania somnifera

Q2I015

activity is assayed radiometrically using UDP-[U-14C] glucose, at pH 8.0 and 37°C

671624

0.059

beta-sitosterol

Arabidopsis thaliana

-

-

671624

0.0045

brassicasterol

Withania somnifera

Q2I015

activity is assayed radiometrically using UDP-[U-14C] glucose, at pH 8.0 and 37°C

671624

0.03

brassicasterol

Arabidopsis thaliana

-

-

671624

0.056

cholesterol

Arabidopsis thaliana

-

-

671624

0.0659

cholesterol

Kluyveromyces lactis

Q6CUV2

pH 7.8, 30°C

736786

0.0672

cholesterol

Ogataea angusta

A7KAK6

pH 7.8, 30°C

736786

0.04

dehydroepiandrosterone

Withania somnifera

Q2I015

activity is assayed radiometrically using UDP-[U-14C] glucose, at pH 8.0 and 37°C

671624

0.043

dehydroepiandrosterone

Arabidopsis thaliana

-

-

671624

0.119

dehydroepiandrosterone

Withania somnifera

-

for the cytosolic enzyme

672427

0.004

ergosterol

Withania somnifera

Q2I015

activity is assayed radiometrically using UDP-[U-14C] glucose, at pH 8.0 and 37°C

671624

0.035

ergosterol

Arabidopsis thaliana

-

-

671624

0.005

pregnenolone

Withania somnifera

-

for the cytosolic enzyme

672427

0.006

pregnenolone

Withania somnifera

Q2I015

activity is assayed radiometrically using UDP-[U-14C] glucose, at pH 8.0 and 37°C

671624

0.008

pregnenolone

Arabidopsis thaliana

-

-

671624

0.005

sitosterol

Sinapis alba

-

-

637771

0.0056

sitosterol

Physarum polycephalum

-

-

637766

0.2

sitosterol

Zea mays

-

-

637781

0.2

sitosterol

Zea mays

-

strongly lowered by phosphatidylcholine and phosphatidylglycerol

637768

0.24 - 0.54

sitosterol

Avena sativa

-

-

637782

0.003

solasodine

Arabidopsis thaliana

-

-

671624

0.007

solasodine

Withania somnifera

Q2I015

activity is assayed radiometrically using UDP-[U-14C] glucose, at pH 8.0 and 37°C

671624

0.027

stigmasterol

Withania somnifera

Q2I015

activity is assayed radiometrically using UDP-[U-14C] glucose, at pH 8.0 and 37°C

671624

0.043

stigmasterol

Arabidopsis thaliana

-

-

671624

0.125

stigmasterol

Withania somnifera

-

for the cytosolic enzyme

672427

0.025

transandrosterone

Withania somnifera

Q2I015

activity is assayed radiometrically using UDP-[U-14C] glucose, at pH 8.0 and 37°C

671624

0.059

transandrosterone

Arabidopsis thaliana

-

-

671624

0.008

UDP-glucose

Withania somnifera

Q2I015

activity is assayed radiometrically using UDP-[U-14C] glucose, at pH 8.0 and 37°C

671624

0.014

UDP-glucose

Withania somnifera

-

for the cytosolic enzyme

672427

0.01429

UDP-glucose

Solanum melongena

-

pH 7.3, 30°C

690224

0.023

UDP-glucose

Gossypium hirsutum

-

lecithin causes a 2fold increase in Km

637777

0.025

UDP-glucose

Zea mays

-

-

637780

0.025

UDP-glucose

Arabidopsis thaliana

-

-

671624

0.04

UDP-glucose

Zea mays

-

-

637781

0.04

UDP-glucose

Zea mays

-

slightly lowered by phosphatidylcholine and phosphatidylglycerol

637768

0.08

UDP-glucose

Sinapis alba

-

-

637771

0.12

UDP-glucose

Physarum polycephalum

-

-

637767

0.18

UDP-glucose

Physarum polycephalum

-

-

637766

0.34

UDP-glucose

Avena sativa

-

-

637782