Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.4.1.17: glucuronosyltransferase

This is an abbreviated version!
For detailed information about glucuronosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.17

Reaction

UDP-alpha-D-glucuronate
+
acceptor
=
UDP
+
acceptor beta-D-glucuronoside

Synonyms

1-naphthol glucuronyltransferase, 1-naphthol-UDP-glucuronosyltransferase, 17-OH steroid UDPGT, 17beta-hydroxysteroid UDP-glucuronosyltransferase, 1A10, 3,4-catechol estrogen specific UDPGTh-2, 3-OH androgenic UDPGT, 3alpha-hydroxysteroid UDP-glucuronosyltransferase, 4-hydroxybiphenyl UDP-glucuronosyltransferase, 4-methylumbelliferone UDP-glucuronosyltransferase, 4-nitrophenol UDP-glucuronosyltransferase, 4-nitrophenol UDP-glucuronyltransferase, 4-nitrophenol UDPGT, bile acid uridine 5'-diphosphoglucuronyltransferase, bilirubin glucuronyltransferase, bilirubin monoglucuronide glucuronyltransferase, bilirubin UDP-glucuronosyltransferase, bilirubin UDPglucuronosyltransferase, bilirubin UDPGT, bilirubin uridine diphosphoglucuronyltransferase, bilirubin-specific UDPGT isozyme 1, bilirubin-specific UDPGT isozyme 2, ciramadol UDP-glucuronyltransferase, DP-glucuronosyltransferase 1A3, EC 2.4.1.107, EC 2.4.1.108, EC 2.4.1.42, EC 2.4.1.59, EC 2.4.1.61, EC 2.4.1.76, EC 2.4.1.77, EC 2.4.1.84, estriol UDP-glucuronosyltransferase, estrone UDP-glucuronosyltransferase, GlcAT-P, GlcAT-S, glucuronosyltransferase, uridine diphospho-, glucuronosyltransferase, uridine diphosphoglucuronate-1,2-diacylglycerol, glucuronosyltransferase, uridine diphosphoglucuronate-4-hydroxybiphenyl, glucuronosyltransferase, uridine diphosphoglucuronate-bilirubin, glucuronosyltransferase, uridine diphosphoglucuronate-estradiol, glucuronosyltransferase, uridine diphosphoglucuronate-estriol, glucuronosyltransferase, uridine diphosphoglucuronate-estriol 16alpha-, glucuronyltransferase, glucuronyltransferase, uridine diphospho-GT, HUG-BR1, HUG-BR2, inositol phosphorylceramide glucuronosyltransferase1, IPUT1, monUGT1A6, More, morphine glucuronyltransferase, p-hydroxybiphenyl UDP glucuronyltransferase, p-nitrophenol UDP-glucuronosyltransferase, p-nitrophenol UDP-glucuronyltransferase, p-nitrophenylglucuronosyltransferase, p-phenylphenol glucuronyltransferase, phenol-metabolizing UDP-glucuronosyltransferase, phenyl-UDP-glucuronosyltransferase, PNP-UDPGT, UDP glucuronate-estradiol-glucuronosyltransferase, UDP glucuronate-estriol glucuronosyltransferase, UDP glucuronic acid transferase, UDP glucuronosyltransferase, UDP glucuronosyltransferase 1A4, UDP glucuronosyltransferase 2B10, UDP glucuronyltransferase, UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase, UDP-glucuronate-bilirubin glucuronyltransferase, UDP-glucuronosyl-transferase 1A1, UDP-glucuronosyltransferase, UDP-glucuronosyltransferase 1A, UDP-glucuronosyltransferase 1A1, UDP-glucuronosyltransferase 1A10, UDP-glucuronosyltransferase 1A3, UDP-glucuronosyltransferase 1A4, UDP-glucuronosyltransferase 1A5, UDP-glucuronosyltransferase 1A6, UDP-glucuronosyltransferase 1A7, UDP-glucuronosyltransferase 1A8, UDP-glucuronosyltransferase 1A9, UDP-glucuronosyltransferase 2, UDP-glucuronosyltransferase 2A3, UDP-glucuronosyltransferase 2B10, UDP-glucuronosyltransferase 2B15, UDP-glucuronosyltransferase 2B17, UDP-glucuronosyltransferase 2B7, UDP-glucuronosyltransferase-1A10, UDP-glucuronosyltransferases 2B15, UDP-glucuronosyltransferases 2B7, UDP-glucuronyltransferase, UDPGA transferase, UDPGA-glucuronyltransferase, UDPglucuronate beta-D-glucuronosyltransferase, UDPglucuronosyltransferase, UDPGT, UFT1A9, UGT, UGT 1A1, UGT 1A10, UGT 1A3, UGT 1A4, UGT 1A6, UGT 1A7, UGT 1A8, UGT 1A9, UGT 2B15, UGT 2B17, UGT 2B4, UGT 2B7, UGT-1A, UGT-1D, UGT-1F, UGT-1J, UGT1-01, UGT1-03, UGT1-04, UGT1-06, UGT1-10, UGT1-9, UGT1.1, UGT1.10, UGT1.3, UGT1.4, UGT1.6, UGT1.9, UGT1A, UGT1A1, UGT1A10, UGT1A10A, UGT1A10B, UGT1A11, UGT1A2, UGT1A2A, UGT1A3, UGT1A4, UGT1A5, UGT1A5A, UGT1A5B, UGT1A6, UGT1A7, UGT1A8, UGT1A9, UGT1D, UGT1E, UGT1F, UGT1J, UGT2A1, UGT2A2, UGT2A3, UGT2B1, UGT2B10, UGT2B11, UGT2B12, UGT2B15, UGT2B17, UGT2B18, UGT2B19, UGT2B2, UGT2B20, UGT2B23, UGT2B28, UGT2B3, UGT2B30, UGT2B31, UGT2B33, Ugt2b34, Ugt2b36, Ugt2b37, UGT2B39, UGT2B4, UGT2B40, UGT2B41, UGT2B42, UGT2B43, UGT2B44, UGT2B45, UGT2B46, UGT2B7, UGT2B8, UGT2B9, UGT330A3, UGT339A2, UGT341A6, UGT342B3, UGT343C3, UGT344D5, UGT344D8, UGT348A3, UGT349A3, UGT350A3, UGT3A1, UGT3A2, uridine 5'-diphospho-glucuronosyltransferase, uridine 5'-diphosphoglucuronyltransferase, uridine diphosphate glucuronosyltransferase, uridine diphosphate glucuronyltransferase, uridine diphosphate-glucuronosyltransferase, uridine diphosphate-glucuronosyltransferase 2 B15, uridine diphosphate-glucuronosyltransferase 2B10, uridine diphosphate-glucuronosyltransferase 2B11, uridine diphosphate-glucuronosyltransferase 2B15, uridine diphosphate-glucuronosyltransferase 2B17, uridine diphosphate-glucuronosyltransferase 2B4, uridine diphosphate-glucuronosyltransferase 2B7, uridine diphosphoglucuronate-bilirubin glucuronosyltransferase, uridine diphosphoglucuronosyltransferase, uridine diphosphoglucuronyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.17 glucuronosyltransferase

Cloned

Cloned on EC 2.4.1.17 - glucuronosyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
2 bilirubin UDP-glucuronyltransferases, expression in COS-1 cells
-
8 different UGT's expressed in baculovirus-infected cells as His-tagged proteins
-
co-expression of His-tagged and HA-tagged isozymes UGT1A6 and UGT1A9 in baculovrisu-infected insect cells
co-expression of isozyme UGT1A6 mutant Y485D with His-tagged isozyme UGT2B7
co-expression of isozyme UGT1A6 mutant Y485D with His-tagged isozyme UGT2B7, co-expression of isozyme UGT1A6 mutant Y485D with isozyme UGT1A4 showing high protein-protein interactions, co-expression of His-tagged and HA-tagged isozymes UGT1A6 and UGT1A9 in baculovirus-infected insect cells
co-expression of isozyme UGT1A6 mutant Y485D with isozyme UGT1A4 showing high protein-protein interactions
coexpression of isozyme UGT2B7 with either CYP3A4, CYP1A2 or CYP2C9 cytochrome P450 enzymes in COS-1 cells, coexpression alters the kinetic properties of isozyme UGT2B7
different isozymes expressed in COS-7
DNA and amino acid sequence determination and analyis of wild-type isozyme UGT1A10, expression of wild-type and mutant isozymes UGT1A10 in COS-1 cells
DNA and amino acid sequence determination and analysis, expression in chinese hamster lung fibroblast V79 cells, sequence comparison, phylogenetic analysis
-
DNA and amino acid sequence determination and analysis, screening of dog cDNA library, expression in chinese hamster lung fibroblast V79 cells, sequence comparison, phylogenetic analysis
DNA and amino acid sequence determination, realtime RT-PCR analysis
effect of female hormones progesterone, oestradiol, oestriol, or oestrone on the promoter activities of relevant UGTs in Hep-G2 cells, real-time reverse transcription-PCR analysis, transcriptional regulation of isozyme UGT1A1, overview
effect of female hormones progesterone, oestradiol, oestriol, or oestrone on the promoter activities of relevant UGTs in HepG2 cells, real-time reverse transcription-PCR analysis, overview
effect of female hormones progesterone, oestradiol, oestriol, or oestrone on the promoter activities of relevant UGTs in HepG2 cells, real-time reverse transcription-PCR analysis, transcriptional regulation of isozyme UGT2B7, overview
estriol UDPGT, isozyme with pI 7.4
-
expressed in a baculovirus-Sf9 cell system
expressed in baculovirus-infected insect cells
expressed in baculovirus-infected insect cells and human B-lymphoblastoid cells
-
expressed in Chinese hamster V-79 cells
-
expressed in COS-7 cells
-
expressed in COS-7-H25 and HP1 cells
-
expressed in Escherichia coli BL21-DE3 cells
-
expressed in HEK-293 and CHO cells
-
expressed in HEK-293 cells
-
expressed in HEK293 cells
expressed in HK293 cells
-
expressed in in Sf9 insect cells
expressed in Saccharomyces cerevisiae strain AH22
expressed in yeast AH22 cells
-
expression in baculovirus-infected insect cells
-
expression in Cos-1 cells
expression in COS7 cells
expression in HEK cells
expression in HEK-293 cell
expression in HEK-293 cells
expression in insect cell
expression in yeast strain AH22
expression of diverse isozymes in a lymphoblast expression system, overview
expression of His-tagged enzyme in baculovirus-infected Sf9 insect cells
expression of His-tagged isozymes UGT1A10 or UGT1A7, and of mutant constructurs in COS-1 cells
expression of isoform UGT1A4 in HEK-293 cell
-
expression of isozyme UGT1A1 in baculovirus-infected insect cells
expression of isozyme UGT1A1 in insect cells using the baculovirus infection system
expression of isozyme UGT1A10 as HA-tagged or CFP-fusion protein in COS cells
expression of isozyme UGT1A10 in insect cells using the baculovirus infection system
expression of isozyme UGT1A3 in insect cells using the baculovirus infection system
expression of isozyme UGT1A4 in insect cells using the baculovirus infection system
expression of isozyme UGT1A4 in Spodoptera frugiperda Sf9 cell microsomal membranes, expression analysis, overview
expression of isozyme UGT1A6 in insect cells using the baculovirus infection system
expression of isozyme UGT1A7 in insect cells using the baculovirus infection system
expression of isozyme UGT1A8 in baculovirus-infected insect cells
expression of isozyme UGT1A8 in insect cells using the baculovirus infection system
expression of isozyme UGT1A9 in insect cells using the baculovirus infection system
expression of isozyme UGT1A9 lacking 45 residues of the C-terminus including the trans-membrane helix, enzyme mutant is His6-tagged at the shortened C-terminus, detergent-free expression as soluble protein in insect cells
expression of isozyme UGT2B10 in Spodoptera frugiperda Sf9 cell microsomal membranes, expression analysis, overview
expression of isozyme UGT2B15 in insect cells using the baculovirus infection system
expression of isozyme UGT2B17 in insect cells using the baculovirus infection system
expression of isozyme UGT2B4 in insect cells using the baculovirus infection system
expression of isozyme UGT2B7 as a His-tagged protein in baculovirus-infected insect cells
-
expression of isozyme UGT2B7 in insect cells using the baculovirus infection system
expression of isozymes in COS-1 cells
expression of isozymes in COS-1 cells, DNA sequence determination and analysis of isozyme UGT1A9
expression of isozymes UGT1A1, UGT1A6, and UGT1A9 in HEK-293 cells
expression of several human isozymes in Spodoptera frugiperda Sf9 cells using the baculovirus transfection method
-
expression of theUGT 1 locus in transgenic mice provides only a unique opportunity to examine the regulatory properties that control the tissue-specific and xenobiotic receptor-elicited expression patterns of the individual UGT1A genes and also enriches an understanding of how the UGT1 locus may be regulated at times where changes are apparent in the physiological levels of circulating hormones
expression of theUGT1 locus in transgenic mice provides only a unique opportunity to examine the regulatory properties that control the tissue-specific and xenobiotic receptor-elicited expression patterns of the individual UGT1A genes and also enriches an understanding of how the UGT1 locus may be regulated at times where changes are apparent in the physiological levels of circulating hormones
expression of UGT isozymes in COS-1 cells with co-localization of isozyme UGT1A7His and PKCepsilon and of isoyzme UGT1A10His andPKCalpha orPKCgamma
-
expression of UGT1A and UGT2B isozymes in HEK293 cells
-
expression of UGT1A1 isozyme as HA-tagged or CFP-fusion protein in COS cells
expression of UGT1A10 in baculovirus-infected Sf9 insect cells as His-tagged protein
expression of UGT1A3 as HA-tagged or CFP-fusion protein in COS cells
expression of UGT1A4 as HA-tagged or CFP-fusion protein in COS cells
expression of UGT1A6 as HA-tagged or CFP-fusion protein in COS cells
expression of UGT1A7 as HA-tagged or CFP-fusion protein in COS cells
expression of UGT1A8 as HA-tagged or CFP-fusion protein in COS cells
expression of UGT1A9 isozyme as HA-tagged or CFP-fusion protein in COS cells
expression of wild-type and mutant D256N enzymes in COS-1 cells
expression of wild-type and mutant isozymes as C-terminal Histagged fusion proteins in baculovirus-infected insect cells, expression levels, overview
-
expression of wild-type and mutant isozymes in Pichia pastoris
expression of wild-type isozyme UGR2B15, and of chimeric mutants in HEK-293 cells
expression of wild-type isozyme UGT1A10 in insect cells, overview
expression of wild-type isozyme UGT1A7 in insect cells, overview
expression of wild-type isozyme UGT1A8 in insect cells, overview
expression of wild-type isozyme UGT1A9 and mutants in HEK-293 cells, expression of wild-type isozyme UGT1A9 in insect cells, expression levels, overview
expression of wild-type isozyme UGT2B7, and of chimeric mutants in HEK-293 cells
functional expression of FLAG-tagged enzymes GlcAT-P and GlcAT-S in Escherichia coli strain BL21 as soluble proteins
-
gene IPUT1, functional enzyme overexpression in Saccharomyces cerevisiae, coexpression with a human UDP-GlcA transporter, GIPCs from Saccharomyces cerevisiae do not contain GlcA. Production of GlcA-IPC in yeast
gene UGT1A1, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As
gene UGT1A1, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As
gene UGT1A1, expression analysis and mRNA levels in healthy and hepatitis B virus-positive liver microsomes, overview
gene UGT1A10, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As
gene UGT1A10, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As
gene UGT1A11, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As
gene UGT1A2, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As
gene UGT1A3, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As
gene UGT1A3, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As
gene UGT1A3, recombinant expression of His-tagged enzyme in Spodoptera frugiperda Sf9 cells via baculovirus transfection
gene UGT1A4, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As
gene UGT1A4, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As
gene UGT1A4, expression analysis and mRNA levels in healthy and hepatitis B virus-positive liver microsomes, overview
gene UGT1A4, recombinant expression of His-tagged enzyme in Spodoptera frugiperda Sf9 cells via baculovirus transfection
gene UGT1A5, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As
gene UGT1A6, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As
gene UGT1A6, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As
gene UGT1A7, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As
gene UGT1A7, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As
gene UGT1A8, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As
gene UGT1A8, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As
gene UGT1A9, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As
gene UGT1A9, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As
gene UGT1A9, expression analysis and mRNA levels in healthy and hepatitis B virus-positive liver microsomes, overview
gene UGT2A1, recombinant expression of C-terminally His-tagged enzyme in Spodoptera frugiperda Sf9 cells via baculovirus transfection
Q6UWM9, Q9Y4X1
gene UGT2A3, located on chromosome 4q13, DNA and amino acid sequence determination and analysis, the UGT2A3 proximal promoter contains putative HNF1alpha, CDX2, PXR, and GR consensus elements, sequence comparisons, expression of UGT2A3 in Spodoptera frugiperda SF21 cells using the baculovirus transfection system
gene UGT2B10, recombinant expressin in HEK-293T cells
gene UGT2B10, recombinant expression of His-tagged enzyme in Spodoptera frugiperda Sf9 cells via baculovirus transfection
gene UGT2B7, DNA and amino acid sequence determination and analysis, genotyping, three non-synonymous single nucleotide polymorphisms are identified, expression of CFP-tagged, YFP-tagged and HA-tagged UGT2B7 wild-type and mutant allozymes in Spodoptera frugiperda Sf9 cells via baculovirus transfection
gene UGT2B7, expression analysis and mRNA levels in healthy and hepatitis B virus-positive liver microsomes, overview
gene UGT3A1, functional recombinant overexpression of His-tagged isozyme in HEK-293 cells, subcloning in Escherichia coli TOP10 cells
gene UGT3A2, recombinant overexpression in HEK-293 cells
heterologous expression in insect Sf9 cells
heterologously expression in Saccharomyces cerevisiae
IPUT1 overexpression in Saccharomyces Nicotiana benthamiana using the Agrobacterium tumefaciens strain C58-1 transfection method, coexpression with a glucuronosyltransferase, GUX1. Total glucosylceramide levels decrease slightly compared with the p19 control, while levels of GlcN-GlcA-IPC increase
-
isoform UGT1A, expression in HEK-293T cell
-
isoform UGT1A10, expression in insect cell
-
isoform UGT1A6, expression in insect cell
-
isozyme UGT1A10, realtime expression analysis in healthy and malignant breast tissue samples from African American and Caucasian women, overview
isozyme UGT1A3, DNA and amino acid sequence determination and analysis, overexpression of isozyme UGT1A3 in HEK-293 cells
isozyme UGT1A3, DNA and amino acid sequence determination and analysis, overexpression of isozymes UGT1A3 and UGT1A8 in HEK-293 cells
isozyme UGT1A4, DNA and amino acid sequence determination and analysis, expression of isozyme UGT1A4 in COS-7 cells, analysis of polymorphisms naturally occuring in a Japanese population
isozyme UGT2B15, sequence comparisons, realtime PCR expression analysis
isozyme UGT2B17, sequence comparisons, realtime PCR expression analysis
isozyme UGT2B7, realtime expression analysis in healthy and malignant breast tissue samples from African American and Caucasian women, overview
overexpression of isozyme UGT1A8 in HEK-293 cells
phylogenetic tree of the 18 human UDP-glucuronosyltransferases
realtime RT-PCR analysis
-
recombinant UGT1A5, expressed in baculovirusinfected insect cells
rhesus UGT1A1 expressed in HK-293 cells
-
several UGT cloned. Persistently increased expression of phenol-UGT in rat hepatocyte nodules, hepatoma H4IIE cells and various rat liver epithelial cell lines. Expressed in human lung carcinoma A549 cells and human breast cancer MCF7 cells
-
stable expression in HEK293 cells, 2 allelic variants UGT2B7H268 and UGT2B7Y268
stable expression of isozyme UGT2B7 Tyr268 variant in HEK-293 cells
stable expression of isozymes UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A7, UGT1A8, UGT1A9, UGT1A10, UGT2B4, UGT2B7, UGT2B15, UGT2B17, and UGT2B28 in HEK-293 cells
-
stable expression of isozymes UGT1A1, UGT1A3, UGT1A6, UGT1A8, UGT1A9, UGT1A10, and UGT2B7 in HEK 293 cells, isozymes UGT2B4, UGT2B7, UGT2B10, and UGT2B15 are inactivated during cell lysis for microsome preparation
-
stable HEK293 cell lines overexpressing either the UGT1A10139Glu or UGT1A10139Lys isoforms are created
the largest subfamily UGT2B is encoded by genes clustered on chromosome 4, most isozymes show genetic polymorphisms
transiently expressed in COS-7 cells and stably expressed in V-79 Chinese hamster lung fibroblasts. 7 human liver UDG-GT cDNA clones isolated
-
UGT1 gene locus, exon organization, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression in HEK-293 cells, overview
Ugt1a enzymes expression analysis in blastocysts, overview
UGT1A1 expressed in HK-293 cells
-
UGT1A1 expressed in HK293 cells
-
UGT1A1 that contains the Y486D mutation (1A1 numbering) is expressed as His-tagged protein in thebaculovirus-infected insect cells
UGT1A3 expressed in COS-7 cells
-
UGT1A6 that contains the Y485D is expressed as His-tagged protein in thebaculovirus-infected insect cells
UGT1A71, UGT1a6 and UGT1A4 expressed in COS-1 cells
-
UGT2B7 expressed in COS-1 and COS-7 cells. UGT from both UGT1A and UGT1B families expressed in colon carcinoma cells Caco-2
-