2.4.1.165: N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase
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For detailed information about N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase, go to the full flat file.
Reaction
Synonyms
acetylgalactosaminyltransferase, uridine diphosphoacetylgalactosamine-acetylneuraminyl(alpha2-->3)galactosyl(beta1-->4)glucosyl beta1-->4-, beta-1,4-N-acetylgalactosyltransferase II, beta4GalNAc-T, beta4GalNAcT-II, CT GalNAc transferase, cytotoxic T cell GalNAc transferase, Galgt2, More, Sd(alpha) beta4GalNAcT-II, Sda-beta-1,4-N-acetylgalactosaminyltransferase, Sda-beta-GalNAc-transferase, UDP-GalNAc:beta1,4-N-acetylgalactosaminyltransferase
ECTree
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Source Tissue
Source Tissue on EC 2.4.1.165 - N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase
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additional information
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enzymic activity correlates with the degree of enterocytic differentiation
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colon mucosa or colon carcinoma cell line CaCo-2, not in cell lines SW-948, SW-948FL, SW-480, SW-48, SW-1417, COLO-205, LOVO or HT-29
detected in various amounts in all cell types studied
additional information
other cell lines than differentiated Caco2 cells or normal colonic mucosa show low level of enzyme
additional information
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other cell lines than differentiated Caco2 cells or normal colonic mucosa show low level of enzyme