2.4.1.152: 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase
This is an abbreviated version!
For detailed information about 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase, go to the full flat file.
Word Map on EC 2.4.1.152
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2.4.1.152
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sialylated
-
fucosylated
-
selectins
-
fuc-tiii
-
n-acetyllactosamine
-
medicine
-
synthesis
-
alpha1,3-fucosylation
-
lewisx
-
fuc-ts
-
fuct-iv
-
alpha-2-l-fucosyltransferase
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analysis
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drug development
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biotechnology
- 2.4.1.152
-
sialylated
-
fucosylated
- selectins
- fuc-tiii
- n-acetyllactosamine
- medicine
- synthesis
-
alpha1,3-fucosylation
- lewisx
- fuc-ts
- fuct-iv
- alpha-2-l-fucosyltransferase
- analysis
- drug development
- biotechnology
Reaction
Synonyms
11639FucT, alpha (1,3) fucosyltransferase, alpha (1,3)-fucosyltransferase, alpha 1,3 fucosyltransferase, alpha 1,3/4 fucosyltransferase Lewis 2, alpha 3-fucosyltransferase IX, alpha(1,3)-fucosyltransferase VII, alpha(1,3)fucosyltransferase IV, alpha(1,3)fucosyltransferase VII, alpha(1-3)fucosyltransferase, alpha-(1,3)-fucosyltransferase, alpha-(1,3)-fucosyltransferase 11, alpha-(1,3)-fucosyltransferase IXa, alpha-(1,3/1,4)-fucosyltransferase, alpha-(1,3/1,4)-FucT, alpha-1,3 FucT-VII, alpha-1,3-fucosyltransferase, alpha-1,3-fucosyltransferase 3, alpha-1,3-fucosyltransferase 9D, alpha-1,3-fucosyltransferase VI, alpha-1,3-FucT3, alpha-13-fucosyltransferase VII, alpha-3-fucosyltransferase, alpha-3-L-fucosyltransferase, alpha1,3 fucosyltransferase, alpha1,3 fucosyltransferase VII, alpha1,3 FucT-VII, alpha1,3-fucosyltransferase, alpha1,3-fucosyltransferase 4, alpha1,3-fucosyltransferase 9, alpha1,3-fucosyltransferase C, alpha1,3-fucosyltransferase IX, alpha1,3-fucosyltransferase V, alpha1,3-fucosyltransferase VI, alpha1,3-fucosyltransferase-F, alpha1,3-FucT, alpha1,3-FucTIX, alpha1,3/4-fucosyltransferase, alpha1,3/4-fucosyltransferase VI, alpha1,3FT, alpha1,3fucosyltransferase-VII, alpha1-3 fucosyltransferase, alpha1-3 fucosyltransferase-VII, alpha1-3 FucT, alpha1->3fucosyltransferase, alpha3-fucosyltransferase, alpha3-fucosyltransferase IX, alpha3-fucosyltransferase VII, alpha3-fucosyltransferase-V, alpha3-fucosyltransferase-VI, alpha3/4FucT, CEFT-3, CEFT-4, FT-IV, FT-VII, Fuc-Tb, Fuc-TV, Fuc-TXI, fucosyltransferase, fucosyltransferase 11, fucosyltransferase 4, fucosyltransferase 7, fucosyltransferase IV, fucosyltransferase IX, fucosyltransferase V, fucosyltransferase VI, fucosyltransferase VII, fucosyltransferase, guanosine diphosphofucose-glucoside alpha1-->3-, fucosyltransferase-7, fucosyltransferase-VII, fucosyltransferaseIX, FucT, FucT 9, FucT IX, FucT V, FucT-IX, FucT-VI, FucT-VII, FucT-XI, FucT7, FucT9, FucTC, FucTD, FucTe, FucTVII, FUT VI, FuT-F, FUT-VI, FUT10, FUT11, FUT3, FUT4, FUT5, FUT6, FUT7, Fut9, FUT9a, FutA, FutB, galactoside 3-fucosyltransferase, galactoside 3-L-fucosyltransferase 11, GDL-L-fucose:N-acetyl-beta-D-glucosaminyl alpha-3-L-fucosyltransferase, GDP-Fuc:Galbeta1-4GlcNAc (Fuc to GlcNAc) alpha1-3 fucosyltransferase, GDP-fucose:beta-D-N-acetylglucosaminide 3-alpha-fucosyltransferase, GDP-fucose:Galbeta(1-4)GlcNAc-R alpha(1-3)fucosyltransferase, GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-galactosaminyl-R 3-L-fucosyltransferase, guanosine diphosphofucose glucoside alpha1->3fucosyltransferase, HP_0379, HP_0651, Lewis type alpha1,3-FucT, lewis-negative alpha-3-fucosyltransferase, LEwis-type alpha1,3-fucosyltransferase, Lj4g3v0598850, More, plasma alpha-3-fucosyltransferase, PylT, rat fucosyltransferase VII, rFuc-TVII, rFUT7, sFUT9, UA948FucT, WP-000487420, WP-000487428, WP-000487430, XM_016585847, zebrafisha1-3fucosyltrasferase 1, zFT1
ECTree
2.4.1.152 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferaseAdvanced search results
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Reference on EC 2.4.1.152 - 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Foster, C.S.; Gillies, D.R.B.; Glick, M.C.
Purification and characterization of GDP-L-Fuc-N-acetyl-beta-D-glucosaminide alpha1,3 fucosyltransferase from human neuroblastoma cells. Unusual substrate specificities of the tumor enzyme
J. Biol. Chem.
266
3526-3531
1991
Homo sapiens
Sarnesto, A.; Kohlin, T.; Hindsgaul, O.; Vogele, K.; Blaszczyk-Thurin, M.; Thurin, J.
Purification of the beta-N-acetylglucosaminide alpha 1,3-fucosyltransferase from human serum
J. Biol. Chem.
267
2745-2752
1992
Homo sapiens
Murray, B.W.; Takayama, S.; Schultz, J.; Wong, C.H.
Mechanism and specificity of human alpha-1,3-fucosyltransferase V
Biochemistry
35
11183-11195
1996
Homo sapiens
DeBose-Boyd, R.A.; Nyame, A.K.; Cummings, R.D.
Schistosoma mansoni: characterization of an alpha 1-3 fucosyltransferase in adult parasites
Exp. Parasitol.
82
1-10
1996
Schistosoma mansoni
DeBose-Boyd, R.A.; Nyame, A.K.; Cummings, R.D.
Molecular cloning and characterization of an alpha1,3 fucosyltransferase, CEFT-1, from Caenorhabditis elegans
Glycobiology
8
905-917
1998
Caenorhabditis elegans
Karaivanova, V.; Mookerjea, S.; Hunt, D.; Nagpurkar, A.
Characterization and purification of fucosyltransferases from the cytosol of rat colon
Int. J. Biochem. Cell Biol.
28
165-174
1996
Rattus norvegicus
Mulder, H.; Schachter, H.; Thomas, J.R.; Halkes, K.M.; Kamerling, J.P.; Vliegenthart, J.F.
Identification of a GDP-Fuc:Gal beta 1-3GalNAc-R (Fuc to Gal) alpha 1-2 fucosyltransferase and a GDP-Fuc:Gal beta 1-4GlcNAc (Fuc to GlcNAc) alpha 1-3 fucosyltransferase in connective tissue of the snail Lymnaea stagnalis
Glycoconjugate J.
13
107-113
1996
Lymnaea stagnalis
Legault, D.J.; Kelly, R.J.; Natsuka, Y.; Lowe, J.B.
Human alpha(1,3/1,4)-fucosyltransferases discriminate between different oligosaccharide acceptor substrates through a discrete peptide fragment
J. Biol. Chem.
270
20987-20996
1995
Homo sapiens
Holmes, E.H.; Yen, T.Y.; Thomas, S.; Joshi, R.; Nguyen, A.; Long, T.; Gallet, F.; Maftah, A.; Julien, R.; Macher, B.A.
Human alpha1,3/4 fucosyltransferases. Characterization of highly conserved cysteine residues and N-linked glycosylation sites
J. Biol. Chem.
275
24237-24245
2000
Homo sapiens
Dupuy, F.; Germot, A.; Marenda, M.; Oriol, R.; Blancher, A.; Julien, R.; Maftah, A.
alpha1,4-Fucosyltransferase activity: a significant function in the primate lineage has appeared twice independently
Mol. Biol. Evol.
19
815-824
2002
Homo sapiens, Macaca mulatta
Weston, B.W.; Nair, R.P.; Larsen, R.D.; Lowe, J.B.
Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities
J. Biol. Chem.
267
4152-4160
1992
Homo sapiens (Q11128)
Vo, L.; Lee, S.; Marcinko, M.C.; Holmes, E.H.; Macher, B.A.
Human alpha1,3/4-fucosyltransferases II. A single amino acid at the COOH terminus of FucT III and V alters their kinetic properties
J. Biol. Chem.
273
25250-25255
1998
Homo sapiens
Dupuy, F.; Petit, J.M.; Mollicone, R.; Oriol, R.; Julien, R.; Maftah, A.
A single amino acid in the hypervariable stem domain of vertebrate alpha1,3/1,4-fucosyltransferases determines the type 1/type 2 transfer. Characterization of acceptor substrate specificity of the Lewis enzyme by site-directed mutagenesis
J. Biol. Chem.
274
12257-12262
1999
Bos taurus
Costache, M.; Apoil, P.A.; Cailleau, A.; Elmgren, A.; Larson, G.; Henry, S.; Blancher, A.; Iordachescu, D.; Oriol, R.; Mollicone, R.
Evolution of fucosyltransferase genes in vertebrates
J. Biol. Chem.
272
29721-29728
1997
Pan troglodytes (P56433), Pan troglodytes (P56434)
Cameron, H.S.; Szczepaniak, D.; Weston, B.W.
Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms
J. Biol. Chem.
270
20112-20122
1995
Homo sapiens (P51993), Homo sapiens (Q11128)
Johnson, P.H.; Yates, A.D.; Watkins, W.M.
Human salivary fucosyltransferases: evidence for two distinct alpha-3-L-fucosyltransferase activities one or which is associated with the Lewis blood group Le gene
Biochem. Biophys. Res. Commun.
100
1611-1618
1981
Homo sapiens
Johnson, P.H.; Watkins, W.M.
Sialyl compounds as acceptor substrates for human alpha-3- and alpha-3/4-L-fucosyltransferases
Biochem. Soc. Trans.
13
1119-1120
1985
Homo sapiens
-
Johnson, P.H.; Watkins, W.M.
Separation of an alpha3-L-fucosyltransferase from the blood-group-Le-gene specified alpha-3/4-L-fucosyltransferase in human milk
Biochem. Soc. Trans.
10
445-446
1982
Homo sapiens
-
Prieels, J.P.; Beyers, T.; Hill, R.L.
Human milk fucosyltransferase
Biochem. Soc. Trans.
5
838-839
1977
Homo sapiens
Kannagi, R.
alpha3-Fucosyltransferase-VI (FUT6)
Handbook of Glycosyltransferases and Related Genes; (Taniguchi, N. ; Honk, K. ; Fukuda, M. , eds. )
237-245
2002
Bos taurus, Homo sapiens
-
Kannagi, R.
alpha3-Fucosyltransferase-V (FUT5)
Handbook of Glycosyltransferases and Related Genes; (Taniguchi, N. ; Honk, K. ; Fukuda, M. eds.)
232-236
2002
Cricetulus griseus, Homo sapiens
-
Hood, C.M.; Kelly, V.A.; Bird, M.I.; Britten, C.J.
Measurement of alpha(1-3)fucosyltransferase activity using scintillation proximity
Anal. Biochem.
255
8-12
1998
Homo sapiens
Britten, C.J.; Bird, M.I.
Chemical modification of an alpha3-fucosyltransferase; definition of amino acid residues essential for enzyme activity
Biochim. Biophys. Acta
1334
57-64
1997
Homo sapiens
Hada, T.; Fukui, K.; Ohno, M.; Akamatsu, S.; Yazawa, S.; Enomoto, K.; Yamaguchi, K.; Matsuda, Y.; Amuro, Y.; et al.
Increased plasma alpha-(1->3)-L-fucosyltransferase activities in patients with hepatocellular carcinoma
Glycoconjugate J.
12
627-631
1995
Homo sapiens
Johnson, P.H.; Donald, A.S.; Clarke, J.L.; Watkins, W.M.
Purification, properties and possible gene assignment of an alpha 1,3-fucosyltransferase expressed in human liver
Glycoconjugate J.
12
879-893
1995
Homo sapiens
Robinson, N.E.; de Vries, T.; Davis, R.E.; Stults, C.L.M.; Watson, S.R.; van den Eijnden, D.H.; Macher, B.A.
Expression of fucosylated antigens and alpha1,3 fucosyltransferases in human leukemia cell lines
Glycobiology
4
317-326
1994
Homo sapiens
Holmes, E.H.; Xu, Z.; Sherwood, A.L.; Macher, B.A.
Structure-function analysis of human alpha1->3fucosyltransferases. A GDP-fucose-protected, N-ethylmaleimide-sensitive site in FucT-III and FucT-V corresponds to Ser178 in FucT-IV
J. Biol. Chem.
270
8145-8151
1995
Homo sapiens
Easton, E.W.; Schiphorst, W.E.; van Drunen, E.; van der Schoot, C.E.; van den Eijnden, D.H.
Human myeloid alpha 3-fucosyltransferase is involved in the expression of the sialyl-Lewis(x) determinant, a ligand for E- and P-selectin
Blood
81
2978-2986
1993
Homo sapiens
Candelier, J.J.; Mollicone, R.; Mennesson, B.; Bergemer, A.M.; Henry, S.; Coullin, P.; Oriol, R.
alpha-3-Fucosyltransferases and their glycoconjugate antigen products in the developing human kidney
Lab. Invest.
69
449-459
1993
Homo sapiens
Jezequel-Cuer, M.; N'Guyen-Cong, H.; Biou, D.; Durand, G.
Oligosaccharide specificity of normal human hepatocyte alpha1-3 fucosyltransferase
Biochim. Biophys. Acta
1157
252-258
1993
Homo sapiens
Smith, P.L.; Gersten, K.M.; Petryniak, B.; Kelly, R.J.; Rogers, C.; Natsuka, Y.; Alford, J.A., 3rd; Scheidegger, E.P.; Natsuka, S.; Lowe, J.B.
Expression of the alpha(1,3)fucosyltransferase Fuc-TVII in lymphoid aggregate high endothelial venules correlates with expression of L-selectin ligands
J. Biol. Chem.
271
8250-8259
1996
Mus musculus (Q11131)
Weston, B.W.; Smith, P.L.; Kelly, R.J.; Lowe, J.B.
Molecular cloning of a fourth member of a human alpha(1,3) fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes
J. Biol. Chem.
267
24575-24584
1992
Homo sapiens (P51993), Homo sapiens
Trottein, F.; Mollicone, R.; Fontaine, J.; de Mendonca, R.; Piller, F.; Pierce, R.; Oriol, R.; Capron, M.
Molecular cloning of a putative alpha3-fucosyltransferase from Schistosoma mansoni
Mol. Biochem. Parasitol.
107
279-287
2000
Schistosoma mansoni (Q9NJ24)
Galan, M.C.; Dodson, C.S.; Venot, A.P.; Boons, G.J.
Glycosyltransferase activity can be selectively modulated by chemical modifications of acceptor substrates
Bioorg. Med. Chem. Lett.
14
2205-2208
2004
Homo sapiens
Bryan, M.C.; Lee, L.V.; Wong, C.H.
High-throughput identification of fucosyltransferase inhibitors using carbohydrate microarrays
Bioorg. Med. Chem. Lett.
14
3185-3188
2004
Homo sapiens
Kawar, Z.S.; Haslam, S.M.; Morris, H.R.; Dell, A.; Cummings, R.D.
Novel poly-GalNAcbeta1-4GlcNAc (LacdiNAc) and fucosylated poly-LacdiNAc N-glycans from mammalian cells expressing beta1,4-N-acetylgalactosaminyltransferase and alpha1,3-fucosyltransferase
J. Biol. Chem.
280
12810-12819
2005
Homo sapiens
Miyashiro, M.; Furuya, S.; Sugita, T.
A high-throughput screening system for alpha1-3 fucosyltransferase-VII inhibitor utilizing scintillation proximity assay
Anal. Biochem.
338
168-170
2005
Homo sapiens
Niittymaki, J.; Mattila, P.; Renkonen, R.
Cloning and expression of rat fucosyltransferase VII at sites of inflammation
Apmis
113
613-620
2005
Rattus norvegicus (Q712G6)
Miyashiro, M.; Furuya, S.; Sugita, T.
Development of a sensitive separation and quantification method for sialyl Lewis X and Lewis X involving anion-exchange chromatography: biochemical characterization of alpha1-3 fucosyltransferase-VII
J. Biochem.
136
723-731
2004
Homo sapiens
Niittymaki, J.; Mattila, P.; Renkonen, R.
Differential gene expression of GDP-L-fucose-synthesizing enzymes, GDP-fucose transporter and fucosyltransferase VII
APMIS
114
539-548
2006
Mus musculus, Rattus norvegicus
Satoh, T.; Kanai, Y.; Wu, M.; Yokozeki, H.; Kannagi, R.; Lowe, J.B.; Nishioka, K.
Synthesis of alpha(1,3) fucosyltransferases IV- and VII-dependent eosinophil selectin ligand and recruitment to the skin
Am. J. Pathol.
167
787-796
2005
Homo sapiens, Mus musculus (Q11127), Mus musculus (Q11131)
Rendic, D.; Klaudiny, J.; Stemmer, U.; Schmidt, J.; Paschinger, K.; Wilson, I.B.
Towards abolition of immunogenic structures in insect cells: characterization of a honey-bee (Apis mellifera) multi-gene family reveals both an allergy-related core alpha1,3-fucosyltransferase and the first insect Lewis-histo-blood-group-related antigen-s [erratum: Biochem. J., 402; 603 (2007)]
Biochem. J.
402
105-115
2007
Apis mellifera (Q05GU1)
Rendic, D.; Klaudiny, J.; Stemmer, U.; Schmidt, J.; Paschinger, K.; Wilson, I.B.
Towards abolition of immunogenic structures in insect cells: characterization of a honey-bee (Apis mellifera) multi-gene family reveals both an allergy-related core alpha1,3-fucosyltransferase and the first insect Lewis-histo-blood-group-related antigen-synthesizing enzyme
Biochem. J.
402
603
2007
Apis mellifera (Q05GU1)
Azuma, Y.; Kurusu, Y.; Sato, H.; Higai, K.; Matsumoto, K.
Increased expression of Lewis X and Y antigens on the cell surface and FUT 4 mRNA during granzyme B-induced Jurkat cell apoptosis
Biol. Pharm. Bull.
30
655-660
2007
Homo sapiens
Laeubli, H.; Stevenson, J.L.; Varki, A.; Varki, N.M.; Borsig, L.
L-selectin facilitation of metastasis involves temporal induction of Fut7-dependent ligands at sites of tumor cell arrest
Cancer Res.
66
1536-1542
2006
Mus musculus
Salo, H.; Sievi, E.; Suntio, T.; Mecklin, M.; Mattila, P.; Renkonen, R.; Makarow, M.
Co-expression of two mammalian glycosyltransferases in the yeast cell wall allows synthesis of sLex
FEMS Yeast Res.
5
341-350
2005
Homo sapiens
Hiraoka, N.; Petryniak, B.; Kawashima, H.; Mitoma, J.; Akama, T.O.; Fukuda, M.N.; Lowe, J.B.; Fukuda, M.
Significant decrease in alpha1,3-linked fucose in association with increase in 6-sulfated N-acetylglucosamine in peripheral lymph node addressin of FucT-VII-deficient mice exhibiting diminished lymphocyte homing
Glycobiology
17
277-293
2007
Mus musculus
Piccio, L.; Rossi, B.; Colantonio, L.; Grenningloh, R.; Gho, A.; Ottoboni, L.; Homeister, J.W.; Scarpini, E.; Martinello, M.; Laudanna, C.; DAmbrosio, D.; Lowe, J.B.; Constantin, G.
Efficient recruitment of lymphocytes in inflamed brain venules requires expression of cutaneous lymphocyte antigen and fucosyltransferase-VII
J. Immunol.
174
5805-5813
2005
Mus musculus
Ma, B.; Audette, G.F.; Lin, S.; Palcic, M.M.; Hazes, B.; Taylor, D.E.
Purification, kinetic characterization, and mapping of the minimal catalytic domain and the key polar goups of Helicobacter pylori alpha-(1,3/1,4)-fucosyltransferases
J. Biol. Chem.
281
6385-6394
2006
Helicobacter pylori, Helicobacter pylori NCTC11639, Helicobacter pylori UA948
Münster, J.; Ziegelmüller, P.; Spillner, E.; Bredehorst, R.
High level expression of monomeric and dimeric human alpha1,3-fucosyltransferase V
J. Biotechnol.
121
448-457
2006
Homo sapiens
Petit, D.; Maftah, A.; Julien, R.; Petit, J.M.
En bloc duplications, mutation rates, and densities of amino acid changes clarify the evolution of vertebrate alpha-1,3/4-fucosyltransferases
J. Mol. Evol.
63
353-364
2006
Takifugu rubripes (Q2KQ71), Takifugu rubripes (Q70AG8), Takifugu rubripes (Q70AG9), Takifugu rubripes (Q70AH0), Takifugu rubripes (Q70AH1), Takifugu rubripes (Q70AH2), Takifugu rubripes (Q70AH3), Takifugu rubripes (Q70AH4), Danio rerio (Q2VU44), Danio rerio (Q32WF4), Homo sapiens (Q495W5), Ambystoma tigrinum (Q49ME5), Xenopus tropicalis (Q49ME6), Xenopus laevis (Q6WNG3), Gallus gallus (Q8UVZ3)
Brito, C.; Gouveia, R.; Costa, J.
Stable expression of an active soluble recombinant form of human fucosyltransferase IX in Spodoptera frugiperda Sf9 cells
Biotechnol. Lett.
29
1623-1630
2007
Homo sapiens
Nguyen, K.; van Die, I.; Grundahl, K.M.; Kawar, Z.S.; Cummings, R.D.
Molecular cloning and characterization of the Caenorhabditis elegans alpha1,3-fucosyltransferase family
Glycobiology
17
586-599
2007
Caenorhabditis elegans
Yang, X.; Zhang, Z.; Jia, S.; Liu, Y.; Wang, X.; Yan, Q.
Overexpression of fucosyltransferase IV in A431 cell line increases cell proliferation
Int. J. Biochem. Cell Biol.
39
1722-1730
2007
Homo sapiens (P22083)
Moriguchi, K.; Takemoto, T.; Aoki, T.; Nakakita, S.; Natsuka, S.; Hase, S.
Free oligosaccharides with Lewis x structure expressed in the segmentation period of zebrafish embryo
J. Biochem.
142
213-227
2007
Danio rerio
Brito, C.; Escrevente, C.; Reis, C.A.; Lee, V.M.; Trojanowski, J.Q.; Costa, J.
Increased levels of fucosyltransferase IX and carbohydrate Lewis(x) adhesion determinant in human NT2N neurons
J. Neurosci. Res.
85
1260-1270
2007
Homo sapiens (Q5Q0U2), Homo sapiens
Ahsen, O.; Voigtmann, U.; Klotz, M.; Nifantiev, N.; Schottelius, A.; Ernst, A.; Mueller-Tiemann, B.; Parczyk, K.
A miniaturized high-throughput screening assay for fucosyltransferase VII
Anal. Biochem.
372
96-105
2008
Homo sapiens
Groux-Degroote, S.; Krzewinski-Recchi, M.A.; Cazet, A.; Vincent, A.; Lehoux, S.; Lafitte, J.J.; Van Seuningen, I.; Delannoy, P.
IL-6 and IL-8 increase the expression of glycosyltransferases and sulfotransferases involved in the biosynthesis of sialylated and/or sulfated Lewisx epitopes in the human bronchial mucosa
Biochem. J.
410
213-223
2008
Homo sapiens
Brito, C.; Kandzia, S.; Graca, T.; Conradt, H.S.; Costa, J.
Human fucosyltransferase IX: specificity towards N-linked glycoproteins and relevance of the cytoplasmic domain in intra-Golgi localization
Biochimie
90
1279-1290
2008
Homo sapiens (Q5Q0U2), Homo sapiens
Maeda, T.; Nishimura, S.
FRET-based direct and continuous monitoring of human fucosyltransferases activity: an efficient synthesis of versatile GDP-L-fucose derivatives from abundant D-galactose
Chemistry
14
478-487
2008
Homo sapiens
Wang, H.; Wang, Q.Y.; Zhang, Y.; Shen, Z.H.; Chen, H.L.
Alpha1,3 Fucosyltransferase-VII modifies the susceptibility of apoptosis induced by ultraviolet and retinoic acid in human hepatocarcinoma cells
Glycoconj. J.
24
207-220
2007
Homo sapiens
Lin, C.H.; Lin, C.W.; Khoo, K.H.
Proteomic identification of specific glycosyltransferases functionally implicated for the biosynthesis of a targeted glyco-epitope
Proteomics
8
475-483
2008
Homo sapiens
Gitlin, J.M.; Homeister, J.W.; Bulgrien, J.; Counselman, J.; Curtiss, L.K.; Lowe, J.B.; Boisvert, W.A.
Disruption of tissue-specific fucosyltransferase VII, an enzyme necessary for selectin ligand synthesis, suppresses atherosclerosis in mice
Am. J. Pathol.
174
343-350
2009
Mus musculus
Rouwendal, G.J.; Florack, D.E.; Hesselink, T.; Cordewener, J.H.; Helsper, J.P.; Bosch, D.
Synthesis of Lewis X epitopes on plant N-glycans
Carbohydr. Res.
344
1487-1493
2009
Tetraodon nigroviridis (Q6EV15)
Stacke, C.; Ziegelmueller, P.; Hahn, U.
Comparison of expression systems for human fucosyltransferase IX
Eur. J. Cell Biol.
89
35-38
2010
Homo sapiens
Norden, R.; Nystroem, K.; Olofsson, S.
Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) in virus-infected cells
Glycobiology
19
776-788
2009
Homo sapiens
Wang, Q.Y.; Zhang, Y.; Shen, Z.H.; Chen, H.L.
alpha1,3 fucosyltransferase-VII up-regulates the mRNA of alpha5 integrin and its biological function
J. Cell. Biochem.
104
2078-2090
2008
Homo sapiens
Wang, W.; Hu, T.; Frantom, P.A.; Zheng, T.; Gerwe, B.; Del Amo, D.S.; Garret, S.; Seidel, R.D.; Wu, P.
Chemoenzymatic synthesis of GDP-L-fucose and the Lewis X glycan derivatives
Proc. Natl. Acad. Sci. USA
106
16096-16101
2009
Helicobacter pylori (O25366)
Ponnampalam, A.P.; Rogers, P.A.
Expression and regulation of fucosyltransferase 4 in human endometrium
Reproduction
136
117-123
2008
Homo sapiens
Guo, Q.; Guo, B.; Wang, Y.; Wu, J.; Jiang, W.; Zhao, S.; Qiao, S.; Wu, Y.
Functional analysis of alpha1,3/4-fucosyltransferase VI in human hepatocellular carcinoma cells
Biochem. Biophys. Res. Commun.
417
311-317
2012
Homo sapiens
Laporte, B.; Petit, D.; Rocha, D.; Boussaha, M.; Grohs, C.; Maftah, A.; Petit, J.
Characterization of bovine FUT7 furthers understanding of FUT7 evolution in mammals
BMC Genet.
13
74
2012
Bos taurus (A1XCQ0), Bos taurus
Seelhorst, K.; Stacke, C.; Ziegelmueller, P.; Hahn, U.
N-Glycosylations of human alpha1,3-fucosyltransferase IX are required for full enzyme activity
Glycobiology
23
559-567
2013
Homo sapiens
Li, W.; Zhang, W.; Luo, J.; Cao, A.; Zhang, Y.; Huang, D.; Sheng, W.; Cai, S.; Li, J.
Alpha1,3 Fucosyltransferase VII plays a role in colorectal carcinoma metastases by promoting the carbohydration of glycoprotein CD24
Oncol. Rep.
23
1609-1617
2010
Homo sapiens
Choi, Y.H.; Kim, J.H.; Park, B.S.; Kim, B.G.
Solubilization and iterative saturation mutagenesis of alpha1,3-fucosyltransferase from Helicobacter pylori to enhance its catalytic efficiency
Biotechnol. Bioeng.
113
1666-1675
2016
Helicobacter pylori
Lee, J.; Pandey, R.; Kim, D.; Sohng, J.
Cloning and functional characterization of an alpha-1,3-fucosyltransferase from Bacteroides fragilis
Biotechnol. Bioprocess Eng.
18
843-849
2013
Bacteroides fragilis, Bacteroides fragilis NCTC 9343
-
Yang, X.; Liu, S.; Yan, Q.
Role of fucosyltransferase IV in epithelial-mesenchymal transition in breast cancer cells
Cell Death Dis.
4
e735
2013
Homo sapiens (P22083)
Mickum, M.L.; Rojsajjakul, T.; Yu, Y.; Cummings, R.D.
Schistosoma mansoni alpha1,3-fucosyltransferase-F generates the Lewis X antigen
Glycobiology
26
270-285
2016
Schistosoma mansoni
Kumar, A.; Torii, T.; Ishino, Y.; Muraoka, D.; Yoshimura, T.; Togayachi, A.; Narimatsu, H.; Ikenaka, K.; Hitoshi, S.
The Lewis X-related alpha1,3-fucosyltransferase, Fut10, is required for the maintenance of stem cell populations
J. Biol. Chem.
288
28859-28868
2013
Mus musculus
Ebel, M.E.; Kansas, G.S.
Defining the functional boundaries of the murine alpha1,3-fucosyltransferase Fut7 reveals a remarkably compact locus
J. Biol. Chem.
289
6341-6349
2014
Mus musculus
Choi, Y.H.; Kim, J.H.; Park, B.S.; Kim, B.G.
Solubilization and Iterative Saturation Mutagenesis of alpha1,3-fucosyltransferase from Helicobacter pylori to enhance its catalytic efficiency
Biotechnol. Bioeng.
113
1666-1675
2016
Helicobacter pylori (O25142), Helicobacter pylori 26695 (O25142)
Jung, S.; Park, Y.; Seo, J.
Production of 3-fucosyllactose in engineered Escherichia coli with alpha-1,3-fucosyltransferase from Helicobacter pylori
Biotechnol. J.
14
1800498
2019
Helicobacter pylori (O30511)
Bai, J.; Wu, Z.; Sugiarto, G.; Gadi, M.R.; Yu, H.; Li, Y.; Xiao, C.; Ngo, A.; Zhao, B.; Chen, X.; Guan, W.
Biochemical characterization of Helicobacter pylori alpha1-3-fucosyltransferase and its application in the synthesis of fucosylated human milk oligosaccharides
Carbohydr. Res.
480
1-6
2019
Helicobacter pylori (O30511)
Seelhorst, K.; Pahnke, K.; Meier, C.; Hahn, U.
Tagging glycoproteins with fluorescently labeled GDP-fucoses by Using alpha1,3-fucosyltransferases
ChemBioChem
16
1919-1924
2015
Helicobacter pylori (O30511), Homo sapiens (Q11130), Homo sapiens (Q9Y231)
Mercx, S.; Smargiasso, N.; Chaumont, F.; De Pauw, E.; Boutry, M.; Navarre, C.
Inactivation of the beta(1,2)-xylosyltransferase and the alpha(1,3)-fucosyltransferase genes in Nicotiana tabacum BY-2 cells by a Multiplex CRISPR/Cas9 strategy results in glycoproteins without plant-specific glycans
Front. Plant Sci.
8
403
2017
Nicotiana tabacum
Li, D.; Sun, H.; Bai, G.; Wang, W.; Liu, M.; Bao, Z.; Li, J.; Liu, H.
alpha-1,3-Fucosyltransferase-VII siRNA inhibits the expression of SLex and hepatocarcinoma cell proliferation
Int. J. Mol. Med.
42
2700-2708
2018
Homo sapiens
Zhang, J.; Ju, N.; Yang, X; Chen, L.; Yu, C.
The alpha1,3-fucosyltransferase FUT7 regulates IL-1beta-induced monocyte-endothelial adhesion via fucosylation of endomucin
Life Sci.
192
231-237
2018
Homo sapiens
Yu, J.; Shin, J.; Park, M.; Seydametova, E.; Jung, S.M.; Seo, J.H.; Kweon, D.H.
Engineering of alpha-1,3-fucosyltransferases for production of 3-fucosyllactose in Escherichia coli
Metab. Eng.
48
269-278
2018
Helicobacter pylori (J0U361), Helicobacter pylori (O25142), Helicobacter pylori (O25366), Helicobacter pylori ATCC 43504 (J0U361), Helicobacter pylori ATCC 700392 (O25142), Helicobacter pylori ATCC 700392 (O25366)
Pedersen, C.T.; Loke, I.; Lorentzen, A.; Wolf, S.; Kamble, M.; Kristensen, S.K.; Munch, D.; Radutoiu, S.; Spillner, E.; Roepstorff, P.; Thaysen-Andersen, M.; Stougaard, J.; Dam, S.
N-glycan maturation mutants in Lotus japonicus for basic and applied glycoprotein research
Plant J.
91
394-407
2017
Lotus japonicus
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