2.4.1.146: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase

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For detailed information about beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.146

2.4.1.146

bisecting

l-selectin

hematologic

lymphocyte

glycosyltransferases

osteogenic

sialyl

survivors

n-acetylglucosaminyltransferase-i

o-glycans

synthesis

Reaction

3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl/threonyl-[protein]

3-O-{N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl/threonyl-[protein]

Synonyms

acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-mucin beta(1-3)- (elongating), beta1,3-N-acetylglucosaminyltransferase 3, beta3GlcNAc-T (elongation), core 1 extension beta1,3-N-acetylglucosaminyltransferase, core 1 extension enzyme, core1-beta3GlcNAcT, elongation 3beta-GalNAc transferase, elongation 3beta-GalNAc-transferase, elongation beta3 Gn-T, extended C1 beta3GnT3, GlcNAcT-II, O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II, uridine diphosphoacetylglucosamine-mucin beta(1-3)- (elongating) acetylglucosaminyltransferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.146 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase

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1	General Information
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4	KM Value [mM]
4	Localization
4	Metals/Ions
5	Natural Substrates/ Products (Substrates)
13	Organism
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4	pH Optimum
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Application on EC 2.4.1.146 - beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase

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synthesis

Homo sapiens

Q9Y2A9

use of the recombinant enzyme for construction of the 6-sulfo sialyl Lewis x on extended core1 O-glycans

638301