2.4.1.145: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

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For detailed information about alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.145

2.4.1.145

n-glycans

glcnacs

gnt-iii

glycomic

complex-type

bisecting

fucosyltransferase

tetra-antennary

antennary

hydatidiform

tri-antennary

medicine

synthesis

Reaction

beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein]

beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein]

Synonyms

(GnT)-IVa, (GnT)-IVb, alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase, alpha1,3-mannosyl-beta1,4-N-acetylglucosaminyltransferase IV, beta-acetylglucosaminyltransferase IV, EC 2.4.1.51, GlcNAcTase-IV, GnT IV, GnT-IV, GnT-IVa, GnT-IVb, GnTIVa, Mgat4a, Mgat4b, N-acetylglucosaminyltransferase IV, N-acetylglucosaminyltransferase IVa, N-acetylglucosaminyltransferase-IV, N-acetylglucosaminyltransferase-IVa, N-acetylglucosaminyltransferase-IVb, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV, uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase IV

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.145 alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

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Results	in table
1	Activating Compound
47	AA Sequence
3	Application
1	CAS Registry Number
8	Cloned(Commentary)
63	Disease/ Diagnostics
2	Expression
8	General Information
5	Inhibitors
14	KM Value [mM]
2	Localization
5	Metals/Ions
4	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
26	Organism
4	Pathway
2	PDB ID
3	pH Optimum
2	pH Range
2	Posttranslational Modification
2	Protein Variants
4	Purification (Commentary)
1	Reaction
1	Reaction Type
24	Reference
63	Source Tissue
6	Specific Activity [micromol/min/mg]
1	Storage Stability
29	Substrates and Products (Substrate)
1	Subunits
42	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

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medicine

2 entries

synthesis

Homo sapiens

it is necessary to select appropriate host cell lines according to their glycosyltransferases activity balance to produce glycoproteins with an objective sugar chain structure. The descibed method of grouping cell lines according to their glycosyltransferases activity balance is useful to select appropriate host cells

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