2.4.1.144: beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

This is an abbreviated version!
For detailed information about beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.144

2.4.1.144

bisect

n-glycans

glycosyltransferases

n-acetylglucosamine

fucosyltransferase

gnt-iv

beta-linked

xenoantigens

tetraantennary

e4-pha

medicine

alpha-galactosylation

antennary

glcnac-tiii

trimannosyl

erythroagglutinating

alpha-gal

diagnostics

synthesis

Reaction

beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein]

beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-[beta-D-GlcNAc-(1->4)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein]

Synonyms

(GnT)-III, acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-glycopeptide beta4-, III, beta(1,4)-N-acetylglucosaminyltransferase III, beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, beta-1,4-N-acetylglucosaminyltransferase III, beta-D-mannoside beta-1,4-N-acetylglucosaminyltransferase, beta1,4-N-acetylglucosaminyltransferase III, EC 2.4.1.51, GlcNAc-transferase-III, GlcNAcTase-III, GnT-III, GnTIII, Golgi beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase III, MGAT3, N-acetyl-glucosaminyltransferase III, N-acetylglucosaminyltransferase III, N-acetylglucosaminyltransferase-III, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III, uridine diphosphate (UDP)-N-acetylglucosamin/beta-D-mannoside beta-1,4-N-acetylglucosaminyltransferase III, uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase III

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.144 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

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Results	in table
18	Activating Compound
67	AA Sequence
11	Application
1	CAS Registry Number
38	Cloned(Commentary)
385	Disease/ Diagnostics
14	Expression
28	General Information
23	Inhibitors
7	Ki Value [mM]
23	KM Value [mM]
29	Localization
14	Metals/Ions
16	Molecular Weight [Da]
48	Natural Substrates/ Products (Substrates)
71	Organism
3	Pathway
10	pH Optimum
6	Posttranslational Modification
23	Protein Variants
8	Purification (Commentary)
2	Reaction
1	Reaction Type
68	Reference
120	Source Tissue
23	Specific Activity [micromol/min/mg]
1	Storage Stability
124	Substrates and Products (Substrate)
8	Subunits
104	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]

Organism

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Organism on EC 2.4.1.144 - beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

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forming normal prion protein PrPC and pathogenic prion protein PrPSc

638221

Mus musculus

638223, 674546, 688812, 705381, 722755

no activity in Mus musculus

lung melanoma cell line B16-hm

638220

Rattus norvegicus

7 entries