2.4.1.134: galactosylxylosylprotein 3-beta-galactosyltransferase

This is an abbreviated version!
For detailed information about galactosylxylosylprotein 3-beta-galactosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.134

2.4.1.134

glycosyltransferases

glycans

galts

arabinogalactan-proteins

galactosyltransferases

pollen

rhamnose

glcnac

serine-rich

streptococcal

parasanguinis

lactosylceramide

mucilage

o-glycosylation

adhesin

galnact

hemolytic-uremic

leloir

bacterial-host

2.7.7.12

srrps

tetrasaccharide

sub-golgi

arabinogalactans

longum

globotriaosylceramide

silique

hbecs

alpha-galactosidase

uridylyltransferase

shiga

galactose-1-phosphate

Reaction

[protein]-3-O-(beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine

[protein]-3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine

Synonyms

B3GALT6, beta3GalT I, beta3GalT II, beta3GalT IV, beta3GalT V, beta3GalT VI, beta3GalT6, dbeta3GalTII, galactosyltransferase II, galactosyltransferase, uridine diphosphogalactose-galactosylxylose, galactosyltransferase-2, GalT2, UDPgalactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.134 galactosylxylosylprotein 3-beta-galactosyltransferase

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Results	in table
27	AA Sequence
2	CAS Registry Number
8	Cloned(Commentary)
1	Disease/ Diagnostics
1	Expression
4	General Information
2	KM Value [mM]
4	Localization
1	Metals/Ions
1	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
14	Organism
6	Pathway
1	pH Optimum
4	Protein Variants
2	Purification (Commentary)
1	Reaction
1	Reaction Type
11	Reference
13	Source Tissue
14	Specific Activity [micromol/min/mg]
1	Storage Stability
28	Substrates and Products (Substrate)
15	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
2	Temperature Stability [°C]

Reference

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Reference on EC 2.4.1.134 - galactosylxylosylprotein 3-beta-galactosyltransferase

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637184

Schwartz, N.B.; Rod�n, L.

Biosynthesis of chondroitin sulfate. Solubilization of chondroitin sulfate glycosyltransferases and partial purification of uridine diphosphate-D-galactose:D-xylose galactosyltrans

J. Biol. Chem.

250

5200-5207

1975

Gallus gallus

1150655

637185

Robinson, J.A.; Robinson, H.C.

Initiation of chondroitin sulphate synthesis by beta-D-galactosides. Substrates for galactosyltransferase II

Biochem. J.

227

805-814

1985

Gallus gallus

3924029

637186

Hwang, H.Y.; Olson, S.K.; Brown, J.R.; Esko, J.D.; Horvitz, H.R.

The Caenorhabditis elegans genes sqv-2 and sqv-6, which are required for vulval morphogenesis, encode glycosaminoglycan galactosyltransferase II and xylosyltransferase

J. Biol. Chem.

278

11735-11738

2003

Caenorhabditis elegans (Q9N491)

12584198

637187

Sun, S.; Schilling, B.; Tarantino, L.; Tullius, M.V.; Gibson, B.W.; Munson, R.S., Jr.

Cloning and characterization of the lipooligosaccharide galactosyltransferase II gene of Haemophilus ducreyi

J. Bacteriol.

182

2292-2298

2000

[Haemophilus] ducreyi

10735874

637188

Nakamura, N.; Yamakawa, N.; Sato, T.; Tojo, H.; Tachi, C.; Furukawa, K.

Differential gene expression of beta-1,4-galactosyltransferases I, II and V during mouse brain development

J. Neurochem.

29-38

2001

Mus musculus

11145975

637189

Bai, X.; Zhou, D.; Brown, J.R.; Crawford, B.E.; Hennet, T.; Esko, J.D.

Biosynthesis of the linkage region of glycosaminoglycans. Cloning and activity of galactosyltransferase II, the sixth member of the beta1,3-galactosyltransferase family (beta3GalT6)

J. Biol. Chem.

276

48189-48195

2001

Homo sapiens, Mus musculus

11551958

687791

Ueyama, M.; Takemae, H.; Ohmae, Y.; Yoshida, H.; Toyoda, H.; Ueda, R.; Nishihara, S.

Functional analysis of proteoglycan galactosyltransferase II RNA interference mutant flies

J. Biol. Chem.

283

6076-6084

2008

Drosophila sp. (in: flies)

18165227

688460

Patel, R.Y.; Balaji, P.V.

Fold-recognition and comparative modeling of human beta3GalTI, II, IV, V and VI and beta 3GalNAcT I: Prediction of residues conferring acceptor substrate specificity

J. Mol. Graph. Model.

255-268

2007

Homo sapiens, Homo sapiens (Q96L58), Homo sapiens (Q9Y5Z6)

17212986

702117

Tew, S.R.; Pothacharoen, P.; Katopodi, T.; Hardingham, T.E.

SOX9 transduction increases chondroitin sulfate synthesis in cultured human articular chondrocytes without altering glycosyltransferase and sulfotransferase transcription

Biochem. J.

414

231-236

2008

Homo sapiens

18433381

735420

Malfait,F.; Kariminejad, A.; Van Damme,T.; Gauche, C.; Syx, D.; Merhi-Soussi, F.; Gulberti, S.; Symoens, S.; Vanhauwaert, S.; Willaert, A.; Bozorgmehr, B.; Kariminejad, M.H.; Ebrahimiadib, N.; Hausser, I.; Huysseune, A.; Fournel-Gigleux, S.; De Paepe, A.

Defective initiation of glycosaminoglycan synthesis due to B3GALT6 mutations causes a pleiotropic Ehlers-Danlos-Syndrome-like connective tissue disorder

Am. J. Hum. Genet.

935-945

2013

Homo sapiens (Q96L58)

23664118