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2.4.1.13: sucrose synthase

This is an abbreviated version!
For detailed information about sucrose synthase, go to the full flat file.

Word Map on EC 2.4.1.13

Reaction

NDP-alpha-D-glucose
+
D-fructose
=
NDP
 +
sucrose

Synonyms

AcSuSy, CaSUS1, CaSUS2, CsSUS3, glucosyltransferase, uridine diphosphoglucose-fructose, GmSuSy, LjSUS3, Msus1, MtSucS1, mtSUS, PsnSuSy2, RSuS3, SBSS1, SBSS2, SH1, SS1, SS2, StSUS4, sucrose synthase, sucrose synthase 1, sucrose synthase 2, sucrose synthase 3, sucrose synthase 4, sucrose synthetase, sucrose-UDP glucosyltransferase, sucrose-uridine diphosphate glucosyltransferase, Sus, SUS-SH1, SUS1, SUS2, SUS3, sus4, SUS5, SUS6, SuSy, SuSy1, SuSy2, SuSy3, SuSy4, SuSy5, SuSy6, SuSyAc, SuSyDa, SuSyI, SuSyII, SuSyMr, SuSyNe, UDP-D-Glc:D-Fru 2-alpha-glucosyltransferase, UDP-glucose-fructose glucosyltransferase, UDP-glucose:D-fructose 2-alpha-D-glucosyltransferase, uridine diphosphoglucose-fructose glucosyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.13 sucrose synthase

Inhibitors

Inhibitors on EC 2.4.1.13 - sucrose synthase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,5-dihydroxymethyl-(3S,4R)-dihydroxypyrrolidine
5-deoxy-beta-D-fructose
-
competitive to D-fructose
5-deoxy-D-fructose
10% inhibition
6-Dimethylaminopurine
sucrose-induced activity of sucrose synthase is strongly inhibited by okadaic acid and less by 6-dimethylaminopurine at early stages of regeneration, but not at the stages preceding DNA replication or mitotic activities
actin
-
0.001 mM, 17% inhibition of SuSy1
Ag+
-
at 0.4 mM
arbutin
-
no enzyme activity at 5 mM
Co2+
-
0.05 mM, 20% loss of activity
D-fructose
D-glucose 6-phosphate
Fe2+
-
no activity at 1 mM
Fe3+
-
0.4 mM
fructose
GDP
substrate inhibition occurs in the presence of GDP at concentrations above 10 mM
glucose
GTP
-
sucrose cleavage
imidazole
-
-
iodoacetic acid
N-ethylmaleimide
okadaic acid
sucrose-induced activity of sucrose synthase is strongly inhibited by okadaic acid and less by 6-dimethylaminopurine at early stages of regeneration, but not at the stages preceding DNA replication or mitotic activities
p-hydroxymercuribenzoate
quercetin
the enzyme is tolerant to quercetin up to a concentration of 1.5 mM
Salicine
-
kinetics
sucrose
trehalose 6-phosphate
-
more than 90% inhibition at 1 mM
UDP-glucose
UDPglucose
additional information
-