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evolution
Nitrosomonas europaea sucrose synthase shares the same fold as the GT-B family of the retaining glycosyltransferases
evolution
the enzyme belongs to family 4 of the glycosyltransferases (GT4) and contains an E-X7-E motif that is conserved in members of GT4 and two other GT families, sequence comparisons, overview
malfunction
antisense suppression of Cucumis sativus sucrose synthase 3 reduces hypoxic stress tolerance
malfunction
mutants defective in sucrose synthase display a conditional phenotype in terms of low-oxygen tolerance
malfunction
mutants defective in sucrose synthase display a conditional phenotype in terms of low-oxygen tolerance, lower tolerance of the sus1/sus4 mutant for hypoxia compared to wild-type
malfunction
systemically affected sugar levels and enzyme activities in the shoots of the enzyme mutants, suggesting changes in the source-sink relationship. In sink tissues, sucrose is cleaved to make glucose and fructose available for energy-gaining reactions, macromolecule and amino acid biosynthesis. Heterodera schachtii root infection affects systemic sucrose processing
malfunction
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downregulation of enzyme transcripts significantly delayes fruit ripening
malfunction
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antisense suppression of Cucumis sativus sucrose synthase 3 reduces hypoxic stress tolerance
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malfunction
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mutants defective in sucrose synthase display a conditional phenotype in terms of low-oxygen tolerance
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malfunction
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mutants defective in sucrose synthase display a conditional phenotype in terms of low-oxygen tolerance, lower tolerance of the sus1/sus4 mutant for hypoxia compared to wild-type
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metabolism
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significant and positive association between seed and pod wall dry weight at maturity and peak sucrose synthase activity in seeds of both cultivars and both treatments, irrigation and under a rainout shelter, used to induce terminal drought
metabolism
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starch synthesis
metabolism
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sucrose synthase is a key enzyme regulating the process of rice grain filling meaning conversion of sucrose into starch
metabolism
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sucrose synthase is an integral component of the cellulose synthesis
metabolism
sucrose synthase is involved in UDP-glucose formation, the principal nucleoside diphosphate in the sucrose cleavage reaction and in trehalose biosynthesis
metabolism
sucrose synthase is involved in UDP-glucose formation, the principal nucleoside diphosphate in the sucrose cleavage reaction and in trehalose biosynthesis
metabolism
sucrose synthase is involved in UDP-glucose formation, the principal nucleoside diphosphate in the sucrose cleavage reaction and in trehalose biosynthesis
metabolism
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SuSy is the key enzyme of sucrose metabolism in fruit
metabolism
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the enzyme is important in starcj biosynthesis in potato tubers, changes in SuSy activity do not affect the expression of genes directly involved in starch metabolism, but might lead to important changes in the tuber metabolome and N -glycome
metabolism
Thermosynechococcus vestitus
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interaction between sucrose and glycogen metabolism
metabolism
key enzyme in sucrose metabolism in higher plants
metabolism
the enzyme is involved in the metabolic regulation of the sucrose metabolism, overview
metabolism
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main enzyme involved in sugar breakdown during seed development in isabgol
physiological function
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sucrose synthase is the main sucrose breakdown enzyme in plant sink tissues. Sucrose synthase levels do not limit or regulate carbon transfer in the arbuscular mycorrhizal symbiosis
physiological function
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SuSy activation is associated with the rapid accumulation of sucrose in peach fruit. In sink organs, SuSy displays typically the predominant sucrolytic activity
physiological function
the enzyme is involved in various physiological processes including seed growth and resistance to biotic and abiotic stresses
physiological function
the enzyme is involved in various physiological processes including seed growth and resistance to biotic and abiotic stresses
physiological function
the enzyme is involved in various physiological processes including seed growth and resistance to biotic and abiotic stresses
physiological function
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the enzyme may play little role in determining sucrose accumulation during muskmelon fruit
physiological function
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the enzyme plays an important role in seed filling
physiological function
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the symbiosis-induced Medicago truncatula sucrose synthase gene MtSucS1 is required for an efficient arbuscular mycorrhiza, overview
physiological function
cell wall-localized isoform SusC may provide UDP-glucose for cellulose and callose synthesis from extracellular sugars
physiological function
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enzymic activities in organs of a mutant lacking the activities of isoforms sus1, sus2, sus3, sus4 is about 80-90% of those found in wild-type
physiological function
in sugar-starved cells, the in situ activity of both sucrose synthase and invertase decrease significantly. Following supplementation of root meristems with sugar, invertase remaines inactive, but sucrose synthase activity increases. In sugar-starved cells, sucrose synthase activity is induced more by exogenous sucrose than by glucose. The sucrose-induced activity is strongly inhibited by okadaic acid and less by 6-dimethylaminopurine at early stages of regeneration, but not at the stages preceding DNA replication or mitotic activities. Prolongation of regeneration and a marked decrease in the number of cells resuming proliferation and resulting from the action of inhibitors, are correlated with the process of sucrose synthase activation at the beginning of regeneration from sugar starvation
physiological function
isoform Sus2 knockout mutant shows 30-50% less sucrose synthase activity than wild-type and therefore accumulates 40% more sucrose and 50% less fructose at 15 days after flowering. Mutation does not affect the hexose phosphate pool, but leads to 30-70% less starch in embryo and seed coat. Lipid content is are 55% higher at 9-15 days after flowering. Final seed size and composition are unaltered due to an earlier cessation of growth, thus giving rise to an apparent silent phenotype of mature mutant seeds
physiological function
isoform Sus3 knockout mutant shows 30-50% less sucrose synthase activity than wild-type and therefore accumulates 40% more sucrose and 50% less fructose at 15 days after flowering. Mutation does not affect the hexose phosphate pool, but leads to 30-70% less starch in embryo and seed coat. Lipid content is are 55% higher at 9-15 days after flowering. Final seed size and composition are unaltered due to an earlier cessation of growth, thus giving rise to an apparent silent phenotype of mature mutant seeds
physiological function
mutant lacking isoforms sus1/sus2/sus3/sus4 displays wild-type SUS5 and SUS6 expression levels in leaf, whereas leaves of the sus5/sus6 mutant display wild-type SUS1-4 expression levels. Sucrose synthase activity in leaves and stems of the sus1/sus2/sus3/sus4 and sus5/sus6 plants is about 85% of that of wild-type leaves, which can support normal cellulose and starch biosynthesis
physiological function
sucrose synthase activity is negatively correlated with sucrose and positively correlated with hexose sugars
physiological function
CsSUS3 participates in resisting hypoxic stress, mechanism analysis
physiological function
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enhancing sucrose synthase activity results in increased levels of starch and ADP-glucose in maize seed endosperms
physiological function
Thermosynechococcus vestitus
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in filamentous cyanobacteria, the sucrose cleavage direction plays a key physiological function in carbon metabolism, nitrogen fixation, and stress tolerance
physiological function
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low enzyme activity during cambial growth reduces sink capacity of xylem tissues, thus leading to a considerable increase in the sucrose content in the phloem, which can alter the program of cell development in the cambial zone of Karelian birch. Specific texture of Karelian birch wood emerges as a result of deviations in cambial activity, overview. Upon the decline in cambial activity, the dynamics of changes in enzyme activity in Karelian birch is similar to that in common birch: in xylem tissues the enzyme activity becomes lower but the lowering is not as strong as in Betula pendula var. pendula. In phloem tissues the enzyme activity increases but, in contrast to common birch, this increase is not accompanied by substantial accumulation of starch in parenchymal cells of the phloem
physiological function
role for sucrose synthase as part of the acclimation mechanism to anoxia in dicotyledons. Contribution of sucrose synthases to the fermentative metabolism linked to the ability to survive low-oxygen conditions. Isozyme SUS1 is not required for the sucrose-ethanol transition in seedlings under low-oxygen conditions. Sucrose synthase contributes to ethanol production under anoxia
physiological function
role for sucrose synthase as part of the acclimation mechanism to anoxia in dicotyledons. Contribution of sucrose synthases to the fermentative metabolism linked to the ability to survive low-oxygen conditions. Isozyme SUS4 is not required for the sucrose-ethanol transition in seedlings under low-oxygen conditions. Sucrose synthase contributes to ethanol production under anoxia
physiological function
role for sucrose synthase as part of the acclimation mechanism to anoxia in dicotyledons. Contribution of sucrose synthases to the fermentative metabolism linked to the ability to survive low-oxygen conditions. Sucrose synthase contributes to ethanol production under anoxia
physiological function
role of the sucrose-cleaving enzymes sucrose synthases in the development of endoparasitic nematodes, the cyst forming Heterodera schachtii and the root-knot forming Meloidogyne javanica. The parasites influence the regulation of enzyme transcription, general role of sucrose-degrading enzymes during plant-nematode interactions, overview. Sucrose synthases play particular roles in nematode-induced feeding sites
physiological function
sucrose synthase is a major determinant of sink strength that highly controls the channeling of incoming sucrose into starch and cell wall polysaccharides, the enzyme is involved in production of starch and ADP-glucose
physiological function
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sucrose synthase is considered the first key enzyme for secondary growth because it is a highly regulated cytosolic enzyme that catalyzes the reversible conversion of sucrose and UDP into UDP-glucose and fructose. Enzyme PsnSuSy2 plays a significant role in cleaving sucrose into UDP-glucose and fructose to facilitate cellulose biosynthesis and that promotion of cellulose biosynthesis suppresses lignin biosynthesis
physiological function
the enzyme activity is finely tuned through regulation of their gene expression at different levels and modulation of enzymatic activities by metabolites
physiological function
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enzyme overexpression can significantly improve hull size and grain weight by dynamically regulating cell division and starch accumulation in transgenic rice
physiological function
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guard cell-specific isoform SUS3 overexpression leads to increased enzyme activity, stomatal aperture, stomatal conductance, transpiration rate, net photosynthetic rate and growth
physiological function
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the enzyme generates metabolic energy to fuel sucrose sequestration in the vacuole and supplies substrates for cell wall biosynthesis
physiological function
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the enzyme plays an important role in the regulation of fruit ripening
physiological function
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CsSUS3 participates in resisting hypoxic stress, mechanism analysis
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physiological function
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role for sucrose synthase as part of the acclimation mechanism to anoxia in dicotyledons. Contribution of sucrose synthases to the fermentative metabolism linked to the ability to survive low-oxygen conditions. Sucrose synthase contributes to ethanol production under anoxia
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physiological function
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role for sucrose synthase as part of the acclimation mechanism to anoxia in dicotyledons. Contribution of sucrose synthases to the fermentative metabolism linked to the ability to survive low-oxygen conditions. Isozyme SUS1 is not required for the sucrose-ethanol transition in seedlings under low-oxygen conditions. Sucrose synthase contributes to ethanol production under anoxia
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physiological function
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role for sucrose synthase as part of the acclimation mechanism to anoxia in dicotyledons. Contribution of sucrose synthases to the fermentative metabolism linked to the ability to survive low-oxygen conditions. Isozyme SUS4 is not required for the sucrose-ethanol transition in seedlings under low-oxygen conditions. Sucrose synthase contributes to ethanol production under anoxia
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additional information
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roots of plants deficient in sucrose synthase root isozyme are colonized successfully by arbuscular myccorhizal fungi in a similar levelthan the wild-type plant roots
additional information
a triad of conserved homologous catalytic residues, Arg567, Lys572, and Glu663, in the family is functionally critical in the Nitrosomonas europaea sucrose synthase, structure homology modeling, overview
additional information
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a triad of conserved homologous catalytic residues, Arg567, Lys572, and Glu663, in the family is functionally critical in the Nitrosomonas europaea sucrose synthase, structure homology modeling, overview
additional information
enzyme homology modeling and substrate docking using the crystal structure of Nitrosomonas europaea NeSuS1, PDB ID 4RBN, and the crystal structure of Arabidopsis AtSuS1, PDB ID 3S28, overview
additional information
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enzyme homology modeling and substrate docking using the crystal structure of Nitrosomonas europaea NeSuS1, PDB ID 4RBN, and the crystal structure of Arabidopsis AtSuS1, PDB ID 3S28, overview
additional information
structure-function relationship analysis, overview
additional information
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structure-function relationship analysis, overview
additional information
structure-function relationship analysis, overview
additional information
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structure-function relationship analysis, overview
additional information
structure-function relationship analysis, overview
additional information
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structure-function relationship analysis, overview
additional information
structure-function relationship analysis, overview
additional information
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structure-function relationship analysis, overview
additional information
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structure-function relationship analysis, overview
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additional information
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structure-function relationship analysis, overview
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additional information
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structure-function relationship analysis, overview
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additional information
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structure-function relationship analysis, overview
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