2.4.1.115: anthocyanidin 3-O-glucosyltransferase
This is an abbreviated version!
For detailed information about anthocyanidin 3-O-glucosyltransferase, go to the full flat file.
Word Map on EC 2.4.1.115
-
2.4.1.115
-
anthocyanidins
-
flavonols
-
dihydroflavonol
-
4-reductase
-
flavanone
-
3-hydroxylase
-
3-o-glucoside
-
hybrida
-
delphinidin
-
5-o-glucosyltransferase
-
3-o-glucosylation
-
peonidin
-
myrica
-
antirrhinum
-
ammonialyase
-
leucoanthocyanidins
-
bayberry
-
synthesis
- 2.4.1.115
- anthocyanidins
- flavonols
- dihydroflavonol
-
4-reductase
- flavanone
-
3-hydroxylase
- 3-o-glucoside
- hybrida
- delphinidin
-
5-o-glucosyltransferase
-
3-o-glucosylation
- peonidin
-
myrica
-
antirrhinum
-
ammonialyase
-
leucoanthocyanidins
- bayberry
- synthesis
Reaction
Synonyms
3-GT, 3GT, 3GT1, anthocyanidin 3-O-glucosyltransferase, anthocyanidin 3GT, anthocyanidin-3-O-glucosyltransferase, Ct3GT-A, EC 2.4.1.233, FaGT1, glucosyltransferase, uridine diphosphoglucose-anthocyanidin 3-O-, Ih3GT, L3GT, MrUFGT, pMdUFGT, UDP glucose-anthocyanidin 3-O-glucosyltransferase, UDP-glucose: anthocyanidin 3-O-glucosyltransferase, UDP-glucose: flavonoid 3-O-glucosyltransferase, UDP-glucose:anthocyanidin 3-O-beta-D-glucosyltransferase, UDP-glucose:anthocyanidin 3-O-glucosyltransferase, UDP-glucose:anthocyanidin/flavonol 3-O-glucosyltransferase, UDP-glucose:anthocyanin 3-O-glucosyltransferase, UDP-glucose:cyanidin 3-O-glucosyltransferase, UDP-glucose:cyanidin-3-O-glucosyltransferase, UDP-glucose:flavonoid 3-O-glucosyltransferase, UF3GT, UFGT, UGT78K1, UGT78K6
ECTree
2.4.1.115 anthocyanidin 3-O-glucosyltransferaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 2.4.1.115 - anthocyanidin 3-O-glucosyltransferase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
anthocyanidin + UDP-D-glucose
anthocyanidin 5-O-glucoside + UDP
-
-
-
-
?
anthocyanidin 5-O-glucoside + UDP-D-glucose
anthocyanidin-3,5-O-diglucoside + UDP
-
-
-
-
?
UDP-alpha-D-glucose + 3,7-dihydroxyflavone
UDP + 3-[(beta-D-glucopyranosyl)oxy]-7-hydroxyflavone
-
about 10% of the activity with cyanidin
-
-
?
UDP-alpha-D-glucose + isorhamnetin
UDP + isorhamnetin 3-O-beta-D-glucoside
-
about 25% of the activity with cyanidin
-
-
?
UDP-alpha-D-glucose + kaempferol
UDP + kaempferol 3-O-beta-D-glucoside
-
67% of the activity with cyanidin
-
-
?
UDP-D-glucose + anthocyanidin
UDP + anthocyanidin-3-O-beta-D-glucoside
-
-
-
?
UDP-D-glucose + cyanidin
UDP + cyanidin-3-O-beta-D-glucoside
17% of the activity with delphinidin
-
-
?
UDP-D-glucose + malvidin
UDP + malvidin-3-O-beta-D-glucoside
87% of the activity with delphinidin
-
-
?
UDP-D-glucose + pelargonidin
UDP + pelargonidin-3-O-beta-D-glucoside
29% of the activity with delphinidin
-
-
?
UDP-D-glucose + peonidin
UDP + peonidin-3-O-beta-D-glucoside
77% of the activity with delphinidin
-
-
?
UDP-glucose + (2R,3R)-dihydroquercetin
UDP + (2R,3R)-dihydroquercetin 3-O-beta-D-glucoside
worst substrate
-
-
?
UDP-glucose + anthocyanidin
UDP + anthocyanidin-3-O-beta-D-glucoside
-
-
-
-
?
UDP-glucose + fisetin
UDP + fisetin-3-O-beta-D-glucoside
-
16% of the activity with cyanidin
-
-
?
UDP-glucose + pelargonidin
UDP + pelargonidin-3-O-beta-D-glucoside
-
-
-
?
UDP-glucose + peonidin
UDP + peonidin 3-O-beta-D-glucoside
-
52% of the activity with cyanidin
-
-
?
UDPalpha-D-glucose + galangin
UDP + galangin 3-O-bbeta-D-glucoside
-
about 15% of the activity with cyanidin
-
-
?
UDPglucose + anthocyanidin
UDP + anthocyanidin-3-O-glucoside
-
involved in anthocyanine biosynthesis
-
-
?
UDPglucose + fisetin
UDP + fisetin 3-O-glucoside
-
about 10% of the activity with cyanidin
-
-
?
UDPglucose + kaempferol
UDP + kaempferol 3-O-glucoside
-
about 5% of the activity with cyanidin
-
-
?
UDPglucose + myricetin
UDP + 3-O-glucoside myricetin
-
about 15% of the activity with cyanidin
-
-
?
UDPglucose + peonidin
UDP + peonidin 3-O-beta-D-glucoside
-
about 85% of the activity with cyanidin
-
-
?
UDPglucose + petunidin
UDP + petunidin 3-O-glucoside
-
about 35% of the activity with cyanidin
-
-
?
UDPglucose + quercetin
UDP + quercetin 3-O-glucoside
-
about 15% of the activity with cyanidin
-
-
?
UDP-alpha-D-glucose + cyanidin
UDP + cyanidin 3-O-beta-D-glucoside
-
-
-
-
?
UDP-alpha-D-glucose + cyanidin
UDP + cyanidin 3-O-beta-D-glucoside
-
-
-
?
UDP-alpha-D-glucose + cyanidin
UDP + cyanidin 3-O-beta-D-glucoside
-
-
-
-
?
UDP-alpha-D-glucose + cyanidin
UDP + cyanidin 3-O-beta-D-glucoside
-
-
-
?
UDP-alpha-D-glucose + cyanidin
UDP + cyanidin 3-O-beta-D-glucoside
-
first step of a anthocyanin branch
-
-
?
UDP-alpha-D-glucose + cyanidin
UDP + cyanidin 3-O-beta-D-glucoside
-
-
-
-
?
UDP-alpha-D-glucose + pelargonidin
UDP + pelargonidin 3-O-beta-D-glucoside
-
37% of the activity with cyanidin
-
-
?
UDP-alpha-D-glucose + pelargonidin
UDP + pelargonidin 3-O-beta-D-glucoside
-
-
-
?
UDP-alpha-D-glucose + pelargonidin
UDP + pelargonidin 3-O-beta-D-glucoside
-
-
-
-
?
UDP-alpha-D-glucose + pelargonidin
UDP + pelargonidin 3-O-beta-D-glucoside
-
72% of the activity with cyanidin
-
-
?
UDP-alpha-D-glucose + quercetin
UDP + quercetin 3-O-beta-D-glucoside
-
79% of the activity with cyanidin
-
-
?
UDP-alpha-D-glucose + quercetin
UDP + quercetin 3-O-beta-D-glucoside
no glucosylation with UDP-galactose, UDP-xylose, UDP-glucuronic acid, UDP-mannose, ADP-glucose, CDP-glucose, GDP-glucose or TDP-glucose
-
-
?
UDP-D-glucose + delphinidin
UDP + delphinidin-3-O-beta-D-glucoside
-
-
-
?
UDP-D-glucose + delphinidin
UDP + delphinidin-3-O-beta-D-glucoside
-
-
-
-
?
UDP-D-glucose + delphinidin
UDP + delphinidin-3-O-beta-D-glucoside
best substrate
-
-
?
UDP-D-glucose + petunidin
UDP + petunidin-3-O-beta-D-glucoside
-
-
-
?
UDP-D-glucose + petunidin
UDP + petunidin-3-O-beta-D-glucoside
72% of the activity with delphinidin
-
-
?
UDP-glucose + cyanidin
UDP + cyanidin-3-O-beta-D-glucoside
-
-
-
?
UDP-glucose + delphinidin
UDP + delphinidin 3-O-beta-D-glucoside
-
-
-
?
UDP-glucose + delphinidin
UDP + delphinidin 3-O-beta-D-glucoside
-
-
-
?
UDP-glucose + delphinidin
UDP + delphinidin 3-O-beta-D-glucoside
-
first step of a anthocyanin branch
-
-
?
UDP-glucose + delphinidin
UDP + delphinidin 3-O-beta-D-glucoside
-
95% of the activity with cyanidin
-
-
?
UDP-glucose + delphinidin
UDP + delphinidin 3-O-glucoside
-
about 70% of the activity with cyanidin
-
-
?
UDP-glucose + delphinidin
UDP + delphinidin 3-O-glucoside
-
more slowly than cyanidin
-
?
UDP-glucose + delphinidin
UDP + delphinidin-3-O-beta-D-glucoside
when acceptor substrates are supplied below the inhibitory concentration of cyaniding, the enzyme demonstrates highest activity towards the anthocyanidin delphinidin
-
-
?
UDP-glucose + delphinidin
UDP + delphinidin-3-O-beta-D-glucoside
-
-
-
?
UDP-glucose + delphinidin
UDP + delphinidin-3-O-beta-D-glucoside
-
-
-
?
UDP-glucose + isorhamnetin
UDP + isorhamnetin-3-O-beta-D-glucoside
-
56% of the activity with cyanidin
-
-
?
UDP-glucose + isorhamnetin
UDP + isorhamnetin-3-O-beta-D-glucoside
-
-
-
?
UDP-glucose + isorhamnetin
UDP + isorhamnetin-3-O-beta-D-glucoside
-
-
-
?
UDP-glucose + kaempferol
UDP + kaempferol-3-O-beta-D-glucoside
when acceptor substrates are supplied above the inhibitory concentration of cyanidin, the enzyme demonstrates highest activity for flavonols (quercetin, myricetin, and kaempferol)
-
-
?
UDP-glucose + kaempferol
UDP + kaempferol-3-O-beta-D-glucoside
worst substrate
-
-
?
UDP-glucose + malvidin
UDP + malvidin 3-O-beta-D-glucoside
-
10% of the activity with cyanidin
-
-
?
UDP-glucose + malvidin
UDP + malvidin-3-O-beta-D-glucoside
-
10% of the activity with cyanidin
-
-
?
UDP-glucose + malvidin
UDP + malvidin-3-O-beta-D-glucoside
best substrate
-
-
?
UDP-glucose + myricetin
UDP + myricetin-3-O-beta-D-glucoside
-
104% of the activity with cyanidin
-
-
?
UDP-glucose + myricetin
UDP + myricetin-3-O-beta-D-glucoside
when acceptor substrates are supplied above the inhibitory concentration of cyanidin , the enzyme demonstrates highest activity for flavonols (quercetin, myricetin, and kaempferol)
-
-
?
UDP-glucose + pelargonidin
UDP + pelargonidin 3-O-glucoside
-
about 90% of the activity with cyanidin
-
-
?
UDP-glucose + pelargonidin
UDP + pelargonidin 3-O-glucoside
-
more slowly than cyanidin
-
?
UDP-glucose + peonidin
UDP + peonidin-3-O-beta-D-glucoside
-
42% of the activity with cyanidin
-
-
?
UDP-glucose + quercetin
UDP + quercetin-3-O-beta-D-glucoside
when acceptor substrates are supplied above the inhibitory concentration of cyanidin , the enzyme demonstrates highest activity for flavonols (quercetin, myricetin, and kaempferol)
-
-
?
UDP-glucose + quercetin
UDP + quercetin-3-O-beta-D-glucoside
while the recombinant enzyme preferentially glucosylates the 3 position of quercetin it is also able to glucosylate position 7 to a small extent in the early stages of the time course
-
-
?
UDPglucose + malvidin
UDP + malvidin 3-O-glucoside
-
about 20% of the activity with cyanidin
-
-
?
additional information
?
-
-
no glycosylation of cyanidin 3-glucoside, cyanidin 3-sophoroside, cyanidin 3,4-diglucoside, apigenin, luteolin, naringenin and dihydroquercetin
-
-
?
additional information
?
-
the enzyme catalyzes glucosyl transfer from UDP-glucose to anthocyanidins such as delphinidin
-
-
?
additional information
?
-
-
the enzyme catalyzes glucosyl transfer from UDP-glucose to anthocyanidins such as delphinidin
-
-
?
additional information
?
-
the enzyme catalyzes glucosyl transfer from UDP-glucose to anthocyanidins such as delphinidin
-
-
?
additional information
?
-
-
the enzyme catalyzes glucosyl transfer from UDP-glucose to anthocyanidins such as delphinidin
-
-
?
additional information
?
-
the anthocyanidin- and flavonol-acceptor binding details are almost identical in the enzyme complex structures with anthocyanidin delphinidin and petunidin, and flavonol kaempferol, although the glucosylation activities against each acceptor are significantly different. The 3-hydroxyl groups of the acceptor substrates were located at hydrogen-bonding distances to the Nepsilon2 atom of the His17 catalytic residue, supporting a role for glucosyl transfer to the 3-hydroxyl groups of anthocyanidins and flavonols, substrate recognition, overview. The enzyme shows only low activity with flavonols, i.e. isorhamnetin, quercetin, kaempferol, and myricetin, cf. EC 2.4.1.91
-
-
?
additional information
?
-
-
the anthocyanidin- and flavonol-acceptor binding details are almost identical in the enzyme complex structures with anthocyanidin delphinidin and petunidin, and flavonol kaempferol, although the glucosylation activities against each acceptor are significantly different. The 3-hydroxyl groups of the acceptor substrates were located at hydrogen-bonding distances to the Nepsilon2 atom of the His17 catalytic residue, supporting a role for glucosyl transfer to the 3-hydroxyl groups of anthocyanidins and flavonols, substrate recognition, overview. The enzyme shows only low activity with flavonols, i.e. isorhamnetin, quercetin, kaempferol, and myricetin, cf. EC 2.4.1.91
-
-
?
additional information
?
-
-
no activity with: 3-hydroxyflavone, morin, catechin, epicatechin, naringenin, taxifolin, 5-hydroxyflavone, 7-hydroxyflavone, chrysin, apigenin, quercetin, kaempferol 3-O-glucoside, and anthocyanins. FaGT1 acts exclusively on anthocyanidins and flavonols in vitro. No product is formed when UDP-Gal and UDP-GlcUA are used as sugar donors with pelargonidin or quercetin as acceptor molecules
-
-
?
additional information
?
-
no activity is observed for dihydroflavonol (dihydroquercetin), isoflavone (genistin, genistein and daidzein), (epi)-flavan-3-O-beta-Dl (catechin, epicatechin), 3-deoxyanthocyanidin (apigeninidin), flavonol conjugate (flavonol 3-O-beta-D-glucosides) and anthocyanins (anthocyanidin 3-O-beta-D-glucosides and cyanidin 3-O-beta-D-galactoside). Galactose can be transferred from UDP-galactose to the 3-position of cyanidin and delphinidin with low specificity relative to the analogous glucosyltransferase reactions
-
-
?
additional information
?
-
-
no activity is observed for dihydroflavonol (dihydroquercetin), isoflavone (genistin, genistein and daidzein), (epi)-flavan-3-O-beta-Dl (catechin, epicatechin), 3-deoxyanthocyanidin (apigeninidin), flavonol conjugate (flavonol 3-O-beta-D-glucosides) and anthocyanins (anthocyanidin 3-O-beta-D-glucosides and cyanidin 3-O-beta-D-galactoside). Galactose can be transferred from UDP-galactose to the 3-position of cyanidin and delphinidin with low specificity relative to the analogous glucosyltransferase reactions
-
-
?
additional information
?
-
-
identity of UDP glucose-anthocyanidin 3-O-glucosyltransferase and UDP glucose-flavonol 3-O-glucosyltransferase. The enzyme from wild-type or mutant plants glucosylates flavonols at higher rates than anthocyanidins
-
-
?
additional information
?
-
-
no substrate: anthocyanidin 3-O-glucoside
-
-
?
additional information
?
-
the enzyme is not able to further glucosylate cyanidin 3-O-beta-D-glucoside and it could not use UDP-galactose as a donor substrate
-
-
?
additional information
?
-
-
the enzyme is not able to further glucosylate cyanidin 3-O-beta-D-glucoside and it could not use UDP-galactose as a donor substrate
-
-
?
additional information
?
-
the principal, if not only, role of UDP-glucose:flavonoid 3-O-glucosyltransferase is to glucosylate anthocyanidins in red fruit ripening
-
-
?
additional information
?
-
-
the principal, if not only, role of UDP-glucose:flavonoid 3-O-glucosyltransferase is to glucosylate anthocyanidins in red fruit ripening
-
-
?
additional information
?
-
the enzyme is responsible for a late step in anthocyanin biosynthesis
-
-
?
additional information
?
-
-
the enzyme is responsible for a late step in anthocyanin biosynthesis
-
-
?
additional information
?
-
-
no aglycosylation of apigenin, luteolin, naringenin and dihydroquercetin
-
-
?
