2.4.1.102: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

This is an abbreviated version!
For detailed information about beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.102

2.4.1.102

o-glycans

glycosyltransferases

sialylated

p-selectin

o-linked

selectins

ligand-1

core-2

psgl-1

fuct-vii

st3gals

medicine

poly-n-acetyllactosamine

sialyl-lewis

udp-glcnac:gal

diagnostics

1-3galnac-r

polylactosamine

alpha2,3-sialyltransferase

molecular biology

synthesis

Reaction

O3-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl/threonyl-[protein]

O3-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl/threonyl-[protein]

Synonyms

2beta-1,6-acetylglucosaminyltransferase, acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-mucin beta-(1-6)-, acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-mucin beta-(1-6)-, A, bC2GnT-M, beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3, beta-1,6-N-acetylglucosaminyltransferase, beta1,6-N-acetylglucosaminyltransferase, beta6-N-acetylglucosaminyltransferase, Bo17, C2 beta6GnT1, C2/4GnT, C24GNT, C2GlcNAcT-I, C2GlcNAcT-II, C2GlcNAcT-III, C2GnT, C2GnT-1, C2GnT-I, C2GnT-L, c2GnT-M, C2GnT1, C2GnT2, C2GnT3, C2GNTM, C4GnT, core 2 acetylglucosaminyltransferase, core 2 beta-1, 6-N-acetylglucosaminyltransferase-1, core 2 beta-1,6 N-acetylglucosaminyltransferase, core 2 beta-1,6-N-acetylglucosaminyltransferase, core 2 beta1,6 N-acetylglucosaminyltransferase, core 2 beta1,6 N-acetylglucosaminyltransferase-I, core 2 beta1,6-N-acetyl-glycosaminyltransferase, core 2 beta1,6-N-acetylglucosaminyl transferase 1, core 2 beta1,6-N-acetylglucosaminyltransferase, core 2 beta1,6-N-acetylglucosaminyltransferase I, core 2 beta1,6-N-acetylglucosaminyltransferase-I, core 2 beta6-GlcNAc-transferase, core 2 beta6-N-acetylglucosaminyltransferase, core 2 GlcNAc-T, core 2 N-acetylglucosaminyltransferase, Core 2 N-acetylglucosaminyltransferase 2/M, core 2 N-acetylglucosaminyltransferase M, core 2 N-acetylglucosaminyltransferase-1, core 2 N-acetylglucosaminyltransferase-M, core 2 protein beta-1,6-N-acetylglucosaminyltransferase-mucin type, core 2beta 1,6 N-acetylglucosaminyltransferase, core 2beta-1,6-acetylglucosaminyltransferase, core 6-beta-GlcNAc-T, core 6-beta-GlcNAc-transferase A, core2 1-6-N-glucosaminyltransferase-I, core2 beta(1,6)-N-acetyglucosaminyltransferase-I, core2 beta-1,6-N-acetylglucosaminyltransferase, core2 beta-1,6-N-acetylglucosaminyltransferase-1, Core2beta1,6GnT type M, core2GnT, GCNT1, gcnt3, gcnt4, GnT-III, GNTM, More, mucin-type core 2 1,6-N-acetylglucosaminyltransferase enzyme, mucus-type core 2 beta1,6 N-acetylglucosaminyltransferase, O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I, uridine diphosphoacetylglucosamine-mucin beta-(1-6)-acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-mucin beta-(1-6)-acetylglucosaminyltransferase A

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.102 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

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Results	in table
17	Activating Compound
63	AA Sequence
15	Application
2	CAS Registry Number
31	Cloned(Commentary)
2	Crystallization (Commentary)
392	Disease/ Diagnostics
10	Expression
48	General Information
2	General Stability
44	Inhibitors
8	Ki Value [mM]
73	KM Value [mM]
27	Localization
19	Metals/Ions
3	Molecular Weight [Da]
56	Natural Substrates/ Products (Substrates)
85	Organism
1	Oxidation Stability
3	Pathway
10	PDB ID
14	pH Optimum
1	pH Range
5	Posttranslational Modification
30	Protein Variants
8	Purification (Commentary)
2	Reaction
1	Reaction Type
82	Reference
158	Source Tissue
17	Specific Activity [micromol/min/mg]
13	Storage Stability
325	Substrates and Products (Substrate)
4	Subunits
117	Synonyms
1	Systematic Name
13	Temperature Optimum [°C]
10	Temperature Stability [°C]

Specific Activity

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Specific Activity on EC 2.4.1.102 - beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

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0.0000048

Homo sapiens

normal granulocytes

638292

0.0000056

Homo sapiens

untreated recombinant KM3 leukemia cell line

638284

0.000013

Homo sapiens

unstimulated normal T-lymphocytes

0.00002

CML granulocytes

0.00004

EBV B-cell line from healthy individuals

0.000087

AML cells

0.00015

undifferentiated CaCo-2, colonic adenocarcinoma, cells

638293

0.00034

Homo sapiens

CaCo-2, colonic adenocarcinoma, cells differentiated to enterocytes

638293

0.00067

Homo sapiens

recombinant enzyme in Panc1-MUC1 cells

8.2

mutant enzyme C217S

9.2

wild-type enzyme

additional information

6 entries