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2.4.1.1: glycogen phosphorylase

This is an abbreviated version!
For detailed information about glycogen phosphorylase, go to the full flat file.

Word Map on EC 2.4.1.1

Reaction

[(1->4)-alpha-D-glucosyl]n
+
phosphate
=
[(1->4)-alpha-D-glucosyl]n-1
 +
alpha-D-glucose 1-phosphate

Synonyms

1,4-alpha-glucan phosphorylase, alpha-1,4 glucan phosphorylase, alpha-1,4-glycan phosphorylase, alpha-glucan phosphorylase, alpha-glucan phosphorylase H, alpha-glucan/maltodextrin phosphorylase, alphaGP, amylopectin phosphorylase, amylophosphorylase, CcStP, cyosolic phosphorylase, GlgP, glucan phosphorylase, glucosan phosphorylase, glycogen phosphorylase, glycogen phosphorylase a, glycogen phosphorylase b, glycogen phosphorylase-a, GP, GP b, GPA, GPase, GPase a, GPb, GPBB, GPH, granulose phosphorylase, MalP, maltodextrin phosphorylase, More, muscle glycogen phosphorylase, muscle phosphorylase, muscle phosphorylase a and b, myophosphorylase, PF1535, Phb, PHO, Pho 2, Pho1, phosphorylase a, phosphorylase b, phosphorylase, alpha-glucan, plastidial phosphorylase, polyphosphorylase, potato phosphorylase, RMGPa, rmGPb, SP, starch phosphorylase, starch phosphorylase H, stGP, StP, tGPGG, type L alpha-glucan phosphorylase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.1 glycogen phosphorylase

pH Range

pH Range on EC 2.4.1.1 - glycogen phosphorylase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4 - 10
-
activity range
4 - 8
4.2 - 7.6
-
approx. half-maximal activity at pH 4.2 and 7.6, fast isozyme
5.1 - 7.5
-
approx. half-maximal activity at pH 5.1 and 7.5
5.2 - 7.2
5.2 - 7.5
-
approx. 70% of maximal activity at pH 5.2 and approx. half-maximal activity at pH 7.5
5.4 - 7.9
-
50% of maximal activity at pH 5.4 and 7.9, direction of polysaccharide synthesis
5.4 - 8.2
-
approx. half-maximal activity at pH 5.4 and pH 8.2
5.5 - 9
-
-
5.6 - 7.5
-
approx. half-maximal activity at pH 5.6 and pH 7.5, imidazole buffer, phosphorolysis
5.6 - 8
-
approx. half-maximal activity at pH 5.6 and approx. 65% of maximal activity at pH 8, citrate/phosphate-buffer
5.7 - 7.2
-
approx. half-maximal activity at pH 5.7 and 7.2
5.7 - 8
-
approx. half-maximal activity at pH 5.7 and 8
5.8 - 7.2
-
approx. half-maximal activity at pH 5.8 and 7.2, a-isozyme
5.8 - 7.6
-
approx. half-maximal activity at pH 5.8 and 7.6, b-isozyme
6 - 7.5
6 - 8.6
-
approx. 70% of maximal activity at pH 6 and about half-maximal activity at pH 8.6, Tris-buffer
6.7 - 7.9
-
50% of maximal activity at pH 6.7 and 7.9, direction of glucose-1-phosphate formation
7 - 8.1
-
maximal activity at pH 7, approx. 60% of maximal activity at pH 8.1, glycylglycine buffer, phosphorolysis