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2.4.1.1: glycogen phosphorylase

This is an abbreviated version!
For detailed information about glycogen phosphorylase, go to the full flat file.

Word Map on EC 2.4.1.1

Reaction

[(1->4)-alpha-D-glucosyl]n
+
phosphate
=
[(1->4)-alpha-D-glucosyl]n-1
+
alpha-D-glucose 1-phosphate

Synonyms

1,4-alpha-glucan phosphorylase, alpha-1,4 glucan phosphorylase, alpha-1,4-glycan phosphorylase, alpha-glucan phosphorylase, alpha-glucan phosphorylase H, alpha-glucan/maltodextrin phosphorylase, alphaGP, amylopectin phosphorylase, amylophosphorylase, CcStP, cyosolic phosphorylase, GlgP, glucan phosphorylase, glucosan phosphorylase, glycogen phosphorylase, glycogen phosphorylase a, glycogen phosphorylase b, glycogen phosphorylase-a, GP, GP b, GPA, GPase, GPase a, GPb, GPBB, GPH, granulose phosphorylase, MalP, maltodextrin phosphorylase, More, muscle glycogen phosphorylase, muscle phosphorylase, muscle phosphorylase a and b, myophosphorylase, PF1535, Phb, PHO, Pho 2, Pho1, phosphorylase a, phosphorylase b, phosphorylase, alpha-glucan, plastidial phosphorylase, polyphosphorylase, potato phosphorylase, RMGPa, rmGPb, SP, starch phosphorylase, starch phosphorylase H, stGP, StP, tGPGG, type L alpha-glucan phosphorylase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.1 glycogen phosphorylase

KI Value

KI Value on EC 2.4.1.1 - glycogen phosphorylase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00016
(1S)-1,5-anhydro-D-glucitol-spiro[1.5]-3-(2-naphthyl)-1,4,2-oxathiazole
-
-
0.0082
(1S)-1,5-anhydro-D-glucitol-spiro[1.5]-3-(4-methoxyphenyl)-1,4,2-oxathiazole
-
-
0.0393
(2R,3R,4S,5R,6R)-3,4,5,9-tetrahydroxy-2-hydroxymethyl-7,9-diaza-1-oxa-spiro[4,5]decane-8,10-dione
-
0.0031
(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-2-hydroxymethyl-7,9-diaza-1-oxa-spiro[4,5]decane-8,10-dione
pH 6.8, 30°C
0.00063
(5R,7R,8R,9S,10R)-7-(hydroxymethyl)-3-(2-naphthyl)-1,6-dioxa-2-azaspiro[4,5]dec-2-ene-8,9,10-triol
pH 6.8
0.0066
(5R,7R,8R,9S,10R)-7-(hydroxymethyl)-3-(4-methoxyphenyl)-1,6-dioxa-2-azaspiro[4,5]dec-2-ene-8,9,10-triol
pH 6.8
0.0079
(5R,7R,8R,9S,10R)-7-(hydroxymethyl)-3-(4-toluyl)-1,6-dioxa-2-azaspiro[4,5]dec-2-ene-8,9,10-triol
pH 6.8
0.32
(5R,7R,8S,9S,10R)-8,9,10-trihydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dione
-
pH and temperature not specified in the publication
0.015
(5S,7R,8S,9S,10R)-7-(hydroxymethyl)-3-(4-methoxyphenyl)-6-oxa-2-thia-1,3-diazaspiro[4.5]decane-8,9,10-triol 2,2-dioxide
-
pH and temperature not specified in the publication
0.0051
(5S,7R,8S,9S,10R)-8,9,10-trihydroxy-7-(hydroxymethyl)-2-thioxo-6-oxa-1,3-diazaspiro[4.5]decan-4-one
-
pH and temperature not specified in the publication
0.0031
(5S,7R,8S,9S,10R)-8,9,10-trihydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dione
-
pH and temperature not specified in the publication
0.48
1,3,5-tris-4'-2''-[3'''-C-(beta-D-glucopyranosyl)-1''',2''',4'''-oxadiazol-5'''-yl]ethyl-1',2',3'-triazol-1'-ylmethylbenzene
-
-
0.535
1,3,5-tris[3'-C-(beta-D-glucopyranosyl)-1',2',4'-oxadiazol-5'-yl]-benzene
-
-
3.204
1-(beta-D-glucopyranosyl)-5-(hept-1-yn-1-yl)uracil
-
pH 6.8, 30°C
0.303
1-(beta-D-glucopyranosyl)-5-(pent-1-yn-1-yl)uracil
-
pH 6.8, 30°C
0.0047
1-(beta-D-glucopyranosyl)-5-ethynyluracil
-
pH 6.8, 30°C
0.001
1-(beta-D-glucopyranosyl)-5-iodouracil
-
pH 6.8, 30°C
0.086
1-deoxy-1-methoxycarbonylamino-beta-D-glucopyranose
-
0.191
3-(beta-D-glucopyranosyl)-1-phenyl-1H-1,2,4-triazol-5(4H)-one
pH and temperature not specified in the publication
0.0334
3-(beta-D-glucopyranosyl)-6-pentyl-2,3-dihydro-furano-[2,3-d]pyrimidin-2-one
-
pH 6.8, 30°C
0.0324
3-(beta-D-glucopyranosyl)-6-propyl-2,3-dihydro-furano-[2,3-d]pyrimidin-2-one
-
pH 6.8, 30°C
0.0015
4-S-alpha-D-glucopyranosyl-4-thiomaltotetraose
-
-
0.0116
5-(beta-D-glucopyranosyl)-3-(2-naphthyl)-1,2,4-oxadiazole
-
-
0.0088
5-(beta-D-glucopyranosyl)-3-(4-methylphenyl)-1,2,4-oxadiazole
-
-
0.02 - 1
ADP-glucose
0.033 - 0.11
ADPglucose
47.1
alpha-cyclodextrin
-
with respect to glycogen
3.5
alpha-cyclodextrin dialdehyde
-
-
-
0.07
alpha-D-Glucopyranose-1,2-cyclic phosphate
-
-
0.44 - 18
alpha-D-glucopyranosyl fluoride
1.7
alpha-D-glucose
-
pH 6.8, 30°C
0.1 - 0.4
alpha-D-glucose-1-methylenephosphonate
0.1
alpha-D-glucose-methylenephosphonate
-
70°C, pH not specified in the publication
0.5 - 4.1
arsenate
0.27
ATP
-
-
0.0013
beta-amylase
-
-
-
14.1
beta-cyclodextrin
-
with respect to glycogen
1.9
beta-cyclodextrin dialdehyde
-
-
-
1
beta-D-glucopyranosyl 1-(2-cyclopropylamino-2-oxoacetyl)-amide
-
-
0.92
beta-D-glucopyranosyl 1-(ethoxy(oxo)acetyl)-amide
-
-
0.21
beta-D-glucopyranosyl 1-(methoxy(oxo)acetyl)-amide
-
-
0.71
beta-D-glucopyranosyl 1-oxalylamide
-
-
5.9
beta-D-glucopyranosyl bismethoxyphosphoramidate
pH 6.8, 30°C, versus alpha-D-glucose 1-phosphate, synthesis reaction
0.043
CH3Hg+
pH 6.8, 25°C
1.7
D-glucose
pH and temperature not specified in the publication
1.73
ellagic acid
pH 6.8, 30°C
0.00046
FR258900
-
3.3
fructose 1,6-diphosphate
-
-
5.2
fructose 6-phosphate
-
-
13.4
gallic acid
pH 6.8, 30°C
7.4
gamma-cyclodextrin
-
with respect to glycogen
11.2
gamma-cyclodextrin dialdehyde
-
-
0.02 - 0.03
GDP-glucose
0.9 - 3.3
gluconolactone
0.0031
glucopyranosylidene spirohydantoin
-
-
0.0023 - 0.0028
glucopyranosylidene spirothiohydantoin
2.5 - 4.5
glucose
0.1 - 5.09
glucose 1-phosphate
0.29 - 4.8
glucose 6-phosphate
0.00038
Hg2+
pH 6.8, 25°C
0.02
N-(3-carboxypropanoyl)-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.37
N-(acetylcarbamoyl)-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.049
N-(azidoacetyl)-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.0046
N-(benzoylcarbamoyl)-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
5.9
N-(dimethoxyphosphoryl)-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.01
N-(naphthalen-2-ylcarbonyl)-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.075
N-(trifluoroacetyl)-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.15
N-([4-[(benzyloxy)carbonyl]benzoyl]carbamoyl)-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.032
N-acetyl-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.14
N-carbamoyl-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.081
N-phenyl-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.04868
N-[(2E)-3-(5,6,7,8-tetrahydronaphthalen-2-yl)prop-2-enoyl]-beta-D-glucopyranosylamine
pH and temperature not specified in the publication
0.0035
N-[(2E)-3-(naphthalen-2-yl)prop-2-enoyl]-beta-D-glucopyranosylamine
pH and temperature not specified in the publication
0.00514
N-[(2E)-3-([1,1'-biphenyl]-4-yl)prop-2-enoyl]-beta-D-glucopyranosylamine
pH and temperature not specified in the publication
0.00498
N-[(2E)-3-[4-(propan-2-yl)phenyl]prop-2-enoyl]-beta-D-glucopyranosylamine
pH and temperature not specified in the publication
0.07529
N-[(2R)-2-methyl-3-[4-(propan-2-yl)phenyl]propanoyl]-beta-D-glucopyranosylamine
pH and temperature not specified in the publication
0.3769
N-[(3S)-3-(4-ethylphenyl)butanoyl]-beta-D-glucopyranosylamine
pH and temperature not specified in the publication
0.006
N-[(4-aminobenzoyl)carbamoyl]-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.085
N-[(4-carboxybenzoyl)carbamoyl]-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.0044
N-[(4-chlorobenzoyl)carbamoyl]-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.0063
N-[(4-hydroxybenzoyl)carbamoyl]-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.0032
N-[(4-methoxybenzoyl)carbamoyl]-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.0023
N-[(4-methylbenzoyl)carbamoyl]-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.0033
N-[(4-nitrobenzoyl)carbamoyl]-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.0037
N-[(biphenyl-4-ylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.21
N-[methoxy(oxo)acetyl]-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
0.00825
N-[[([1,1'-biphenyl]-4-yl)oxy]acetyl]-beta-D-glucopyranosylamine
pH and temperature not specified in the publication
0.004
N-[[4-(methoxycarbonyl)benzoyl]carbamoyl]-beta-D-glucopyranosylamine
-
pH and temperature not specified in the publication
4.1
NaAsO2
-
70°C, pH not specified in the publication
0.02 - 7
NaHSO3
0.69 - 14.2
phosphate
0.0035
quercetagetin
-
pH 6.8, 25°C
1
TDP-glucose
-
-
0.06 - 2
UDP-glucose
0.15 - 0.92
UDPglucose